Proffil personol
Arbenigedd sy’n gysylltiedig â NDC y CU
Yn 2015, cytunodd gwladwriaethau sy’n aelodau'r Cenhedloedd Unedig ar 17 o Nodau Datblygu Cynaliadwy (NDC) byd-eang i ddod â thlodi i ben, diogelu’r blaned a sicrhau ffyniant i bawb. Mae gwaith y person hwn yn cyfrannu at y NDC canlynol:
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NDC 2 Dim Newyn -
NDC 3 Iechyd a Llesiant Da
Ôl bys
- 1 Proffiliau Tebyg
Cydweithrediadau a’r prif feysydd ymchwil yn ystod y pum mlynedd ddiwethaf
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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes
Padalino, G., Celatka, C., Rienhoff Jr., H. Y., Kalin, J. H., Cole, P. A., Lassalle, D., Forde-Thomas, J., Chalmers, I., Brancale, A., Grunau, C. & Hoffmann, K., 30 Maw 2023, Yn: Wellcome Open Research. 8, 146, 33 t., 146.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil1 Dyfyniad (Scopus)74 Wedi eu Llwytho i Lawr (Pure) -
Protective human IgE responses are promoted by comparable life-cycle dependent Tegument Allergen-Like expression in Schistosoma haematobium and Schistosoma mansoni infection
Oettle, R. C., Dickinson, H. A., Fitzsimmons, C. M., Sacko, M., Tukahebwa, E. M., Chalmers, I. W., Wilson, S. & Loke, P. (Golygydd), 25 Mai 2023, Yn: PLoS Pathogens. 19, 5, t. e1011037 20 t., e1011037.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil4 Dyfyniadau (Scopus)157 Wedi eu Llwytho i Lawr (Pure) -
Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility
White, R., Sotillo, J., Ancarola, M. E., Borup, A., Boysen, A. T., Brindley, P. J., Buzás, E. I., Cavallero, S., Chaiyadet, S., Chalmers, I. W., Cucher, M. A., Dagenais, M., Davis, C. N., Devaney, E., Duque-Correa, M. A., Eichenberger, R. M., Fontenla, S., Gasan, T. A., Hokke, C. H. & Kosanovic, M. & 22 eraill, , 05 Ion 2023, Yn: Journal of Extracellular Vesicles. 12, 1, 16 t., 12298.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil47 Dyfyniadau (Scopus)134 Wedi eu Llwytho i Lawr (Pure) -
In silico characterisation of the complete Ly6 protein family in Fasciola gigantica supported through transcriptomics of the newly-excysted juveniles
Davey, S. D., Chalmers, I. W., Fernandez-Fuentes, N., Swain, M. T., Smith, D., Abbas Abidi, S. M., Saifullah, M. K., Raman, M., Ravikumar, G., McVeigh, P., Maule, A. G., Brophy, P. M. & Morphew, R. M., 17 Ion 2022, Yn: Molecular Omics. 18, 1, t. 45-56 12 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil8 Dyfyniadau (Scopus)95 Wedi eu Llwytho i Lawr (Pure) -
Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production
Hulme, B. J., Geyer, K. K., Forde-Thomas, J. E., Padalino, G., Phillips, D. W., Ittiprasert, W., Karinshak, S. E., Mann, V. H., Chalmers, I. W., Brindley, P. J., Hokke, C. H. & Hoffmann, K. F., 13 Ion 2022, Yn: PLoS Pathogens. 18, 1, 35 t., e1009828.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil24 Dyfyniadau (Scopus)216 Wedi eu Llwytho i Lawr (Pure) -
Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation
Padalino, G., El-Sakkary, N., Liu, L. J., Liu, C., Harte, D. S. G., Barnes, R. E., Sayers, E., Forde-Thomas, J., Whiteland, H., Bassetto, M., Ferla, S., Johnson, G., Jones, A. T., Caffrey, C. R., Chalmers, I., Brancale, A. & Hoffmann, K. F., 15 Rhag 2021, Yn: European Journal of Medicinal Chemistry. 226, 19 t., 113823.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil14 Dyfyniadau (Scopus)212 Wedi eu Llwytho i Lawr (Pure) -
Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae
Gasan, T. A., Kuipers, M. E., Roberts, G. H., Padalino, G., Forde-Thomas, J. E., Wilson, S., Wawrzyniak, J., Tukahebwa, E. M., Hoffmann, K. F. & Chalmers, I. W., 18 Tach 2021, Yn: PLoS Neglected Tropical Diseases. 15, 11, 26 t., e0009981.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil7 Dyfyniadau (Scopus) -
Schistosoma mansoni venom allergen-like protein 6 (SmVAL6) maintains tegumental barrier function
Perally, S., Geyer, K. K., Farani, P. S. G., Chalmers, I. W., Fernandez-Fuentes, N., Maskell, D. R., Hulme, B. J., Forde-Thomas, J., Phillips, D., Farias, L. P., Collins, J. J. & Hoffmann, K. F., 31 Maw 2021, Yn: International Journal for Parasitology. 51, 4, t. 251-261 11 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil8 Dyfyniadau (Scopus)134 Wedi eu Llwytho i Lawr (Pure) -
Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities
Padalino, G., Chalmers, I. W., Brancale, A. & Hoffmann, K. F., 13 Tach 2020, Yn: Wellcome Open Research. 5, 37 t., 169.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil6 Dyfyniadau (Scopus)103 Wedi eu Llwytho i Lawr (Pure) -
Schistosoma mansoni venom allergen-like proteins: Phylogenetic relationships, stage-specific transcription and tissue localization as predictors of immunological cross-reactivity
Farias, L. P., Chalmers, I. W., Perally, S., Rofatto, H. K., Jackson, C. J., Brown, M., Khouri, M. I., Barbosa, M. M. F., Hensbergen, P. J., Hokke, C. H., Leite, L. C. C. & Hoffmann, K. F., 01 Gorff 2019, Yn: International Journal for Parasitology. 49, 8, t. 593-599 7 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil9 Dyfyniadau (Scopus)201 Wedi eu Llwytho i Lawr (Pure) -
The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets
Whatley, K., Padalino, G., Whiteland, H., Geyer, K. K., Hulme, B. J., Chalmers, I., Forde-Thomas, J., Ferla, S., Brancale, A. & Hoffmann, K., 15 Tach 2019, Yn: PLoS Neglected Tropical Diseases. 13, 11, 24 t., e0007693.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil25 Dyfyniadau (Scopus)272 Wedi eu Llwytho i Lawr (Pure)
Setiau Data Ymchwil
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Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities - Underlying data
Padalino, G., Chalmers, I. W., Brancale, A. & Hoffmann, K., Figshare, 23 Meh 2020
Dangosydd eitem ddigidol (DOI): 10.6084/m9.figshare.12473108, https://figshare.com/articles/Identification_of_6-_piperazin-1-yl_-1_3_5-triazine_as_a_chemical_scaffold_with_broad_anti-schistosomal_activities/12473108
Set ddata
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Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities - Extended data
Padalino, G., Chalmers, I. W., Brancale, A. & Hoffmann, K., Figshare, 23 Meh 2020
Dangosydd eitem ddigidol (DOI): 10.6084/m9.figshare.12546449, https://figshare.com/articles/Identification_of_6-_piperazin-1-yl_-1_3_5-triazine_as_a_chemical_scaffold_with_broad_anti-schistosomal_activities/12546449/2
Set ddata
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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes - Supplementary tables and movies
Padalino, G., Celatka, C. A., Young Rienhoff Jr, H., Kalin, J. H., Cole, P. A., Lassalle, D., Forde-Thomas, J., Chalmers, I. W., Brancale, A., Grunau, C. & Hoffmann, K. F., Figshare, 04 Ion 2023
Dangosydd eitem ddigidol (DOI): 10.6084/m9.figshare.21814623
Set ddata
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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes - Supplementary Figures
Padalino, G., Celatka, C. A., Young Rienhoff Jr, H., Kalin, J. H., A Cole, P., Lassalle, D., Forde-Thomas, J., Chalmers, I. W., Brancale, A., Grunau, C. & Hoffmann, K. F., Figshare, 05 Maw 2023
Dangosydd eitem ddigidol (DOI): 10.6084/m9.figshare.21814710
Set ddata
Ffeil
Toriadau
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Aberystwyth University Researchers Reveal New Findings on Nucleoproteins [Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes [version 1; peer review: 2 approved]]
Forde-Thomas, J., Hoffmann, K. & Chalmers, I.
10 Awst 2023
1 eitem o Sylw ar y cyfryngau
Y Wasg / Cyfryngau: Sylw yn y cyfryngau
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Parasites: Past or Future
Chalmers, I. (Siaradwr)
17 Meh 2015Gweithgaredd: Sgwrs neu gyflwyniad › Cyflwyniad llafar
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National Science and Engineering Week
Chalmers, I. (Cyfranogwr)
17 Ebr 2015Gweithgaredd: Cymryd rhan mewn digwyddiad neu drefnu digwyddiad › Gŵyl neu Arddangosfa
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Parasites: Past or Future talk
Chalmers, I. (Siaradwr)
17 Meh 2014Gweithgaredd: Sgwrs neu gyflwyniad › Cyflwyniad llafar
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National Science Engineering Week
Chalmers, I. (Cyfranogwr)
16 Ebr 2014Gweithgaredd: Cymryd rhan mewn digwyddiad neu drefnu digwyddiad › Gŵyl neu Arddangosfa
Gwobrau
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Queen’s Anniversary Prize 2023
Brophy, P. (Derbynydd), Hamilton, J. (Derbynydd), Hoffmann, K. (Derbynydd), Jones, R. (Derbynydd), Chalmers, I. (Derbynydd), Morphew, R. (Derbynydd), Rinaldi, G. (Derbynydd), Williams, H. (Derbynydd) & Barber, I. (Derbynydd), 2023
Gwobr: Gwobr (gan gynnwys medalau a gwobrau)