Allbwn Ymchwil fesul blwyddyn
Allbwn Ymchwil fesul blwyddyn
Proffil personol
Arbenigedd sy’n gysylltiedig â NDC y CU
Yn 2015, cytunodd gwladwriaethau sy’n aelodau'r Cenhedloedd Unedig ar 17 o Nodau Datblygu Cynaliadwy (NDC) byd-eang i ddod â thlodi i ben, diogelu’r blaned a sicrhau ffyniant i bawb. Mae gwaith y person hwn yn cyfrannu at y NDC canlynol:
Ôl bys
Ewch i ganol y pynciau ymchwil lle mae Josephine Forde-Thomas ar waith. Mae’r labelau pwnc hyn yn dod o waith y person hwn. Gyda’i gilydd maen nhw’n ffurfio ôl bys unigryw.
- 1 Proffiliau Tebyg
Cydweithrediadau a’r prif feysydd ymchwil yn ystod y pum mlynedd ddiwethaf
Cydweithrediad allanol yn ddiweddar ar lefel gwlad/tiriogaeth. Plymiwch i mewn i'r manylion drwy glicio ar y dotiau neu
Allbwn ymchwil
- 18 Erthygl
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Gut microbiota and immune profiling of microbiota-humanised versus wildtype mouse models of hepatointestinal schistosomiasis
Stark, K. A., Rinaldi, G., Costain, A., Clare, S., Tolley, C., Almeida, A., McCarthy, C., Harcourt, K., Brandt, C., Lawley, T. D., Berriman, M., MacDonald, A. S., Forde-Thomas, J. E., Hulme, B. J., Hoffmann, K. F., Cantacessi, C. & Cortés, A., 01 Rhag 2024, Yn: Animal Microbiome. 6, 1, 36.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil2 Wedi eu Llwytho i Lawr (Pure) -
Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes
Padalino, G., Celatka, C., Rienhoff Jr., H. Y., Kalin, J. H., Cole, P. A., Lassalle, D., Forde-Thomas, J., Chalmers, I., Brancale, A., Grunau, C. & Hoffmann, K., 30 Maw 2023, Yn: Wellcome Open Research. 8, 146, 29 t., 146.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil1 Dyfyniad (Scopus)70 Wedi eu Llwytho i Lawr (Pure) -
Modified Hederagenin Derivatives Demonstrate Ex Vivo Anthelmintic Activity against Fasciola hepatica
Chakroborty, A., Pritchard, D., Bouillon, M. E., Cervi, A., Kraehenbuehl, R., Wild, C., Fenn, C., Holdsworth, P. A., Capner, C., Padalino, G., Forde-Thomas, J., Payne, J., Smith, B. G., Fisher, M., Lahmann, M., Baird, M. S. & Hoffmann, K., 03 Gorff 2023, Yn: Pharmaceutics. 15, 7, 15 t., 1869.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil1 Dyfyniad (Scopus)105 Wedi eu Llwytho i Lawr (Pure) -
Pulmonary inflammation promoted by type-2 dendritic cells is a feature of human and murine schistosomiasis
Houlder, E. L., Costain, A. H., Nambuya, I., Brown, S. L., Koopman, J. P. R., Langenberg, M. C. C., Janse, J. J., Hoogerwerf, M. A., Ridley, A. J. L., Forde-Thomas, J. E., Colombo, S. A. P., Winkel, B. M. F., Galdon, A. A., Hoffmann, K. F., Cook, P. C., Roestenberg, M., Mpairwe, H. & MacDonald, A. S., 01 Rhag 2023, Yn: Nature Communications. 14, 1, 12 t., 1863.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil4 Dyfyniadau (Scopus)164 Wedi eu Llwytho i Lawr (Pure) -
Small Molecule Ligands of the BET-like Bromodomain, SmBRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development
Schiedel, M., McArdle, D. J. B., Padalino, G., Chan, A. K. N., Forde-Thomas, J., McDonough, M., Whiteland, H., Beckmann, M., Cookson, R., Hoffmann, K. F. & Conway, S. J., 14 Rhag 2023, Yn: Journal of Medicinal Chemistry. 66, 23, t. 15801-15822 22 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agored1 Dyfyniad (Scopus) -
Using ChEMBL to Complement Schistosome Drug Discovery
Padalino, G., Coghlan, A., Pagliuca, G., Forde-Thomas, J., Berriman, M. & Hoffmann, K., 28 Ebr 2023, Yn: Pharmaceutics. 15, 5, 26 t., 1359.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil2 Dyfyniadau (Scopus)46 Wedi eu Llwytho i Lawr (Pure) -
Flukicidal effects of abietane diterpenoid derived analogues against the food borne pathogen Fasciola hepatica.
Chakroborty, A., Pritchard, D., Bouillon, M. E., Cervi, A., Cookson, A., Wild, C., Fenn, C., Payne, J., Holdsworth, P., Capner, C., O'Neill, J., Padalino, G., Forde-Thomas, J., Gupta, S., Smith, B. G., Fisher, M., Lahmann, M., Baird, M. S. & Hoffmann, K. F., 01 Medi 2022, Yn: Veterinary Parasitology. 309, 9 t., 109766.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil2 Dyfyniadau (Scopus)98 Wedi eu Llwytho i Lawr (Pure) -
Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production
Hulme, B. J., Geyer, K. K., Forde-Thomas, J. E., Padalino, G., Phillips, D. W., Ittiprasert, W., Karinshak, S. E., Mann, V. H., Chalmers, I. W., Brindley, P. J., Hokke, C. H. & Hoffmann, K. F., 13 Ion 2022, Yn: PLOS Pathogens. 18, 1, 35 t., e1009828.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil18 Dyfyniadau (Scopus)137 Wedi eu Llwytho i Lawr (Pure) -
Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation
Padalino, G., El-Sakkary, N., Liu, L. J., Liu, C., Harte, D. S. G., Barnes, R. E., Sayers, E., Forde-Thomas, J., Whiteland, H., Bassetto, M., Ferla, S., Johnson, G., Jones, A. T., Caffrey, C. R., Chalmers, I., Brancale, A. & Hoffmann, K. F., 15 Rhag 2021, Yn: European Journal of Medicinal Chemistry. 226, 19 t., 113823.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil7 Dyfyniadau (Scopus)153 Wedi eu Llwytho i Lawr (Pure) -
Plasmacytoid Dendritic Cells Facilitate Th Cell Cytokine Responses throughout Schistosoma mansoni Infection
Webb, L. M., Phythian-Adams, A. T., Costain, A. H., Brown, S. L., Lundie, R. J., Forde-Thomas, J., Cook, P. C., Jackson-Jones, L. H., Marley, A. K., Smits, H. H., Hoffmann, K. F., Tait Wojno, E. D. & MacDonald, A. S., 31 Awst 2021, Yn: ImmunoHorizons. 5, 8, t. 721-732 12 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agored7 Dyfyniadau (Scopus) -
Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae
Gasan, T. A., Kuipers, M. E., Roberts, G. H., Padalino, G., Forde-Thomas, J. E., Wilson, S., Wawrzyniak, J., Tukahebwa, E. M., Hoffmann, K. F. & Chalmers, I. W., 18 Tach 2021, Yn: PLoS Neglected Tropical Diseases. 15, 11, e0009981.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agored6 Dyfyniadau (Scopus)
Setiau Data Ymchwil
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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes - Supplementary Figures
Padalino, G., Celatka, C. A., Young Rienhoff Jr, H., Kalin, J. H., A Cole, P., Lassalle, D., Forde-Thomas, J., Chalmers, I. W., Brancale, A., Grunau, C. & Hoffmann, K. F., figshare, 05 Maw 2023
Dangosydd eitem ddigidol (DOI): 10.6084/m9.figshare.21814710
Set ddata
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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes - Supplementary tables and movies
Padalino, G., Celatka, C. A., Young Rienhoff Jr, H., Kalin, J. H., Cole, P. A., Lassalle, D., Forde-Thomas, J., Chalmers, I. W., Brancale, A., Grunau, C. & Hoffmann, K. F., figshare, 04 Ion 2023
Dangosydd eitem ddigidol (DOI): 10.6084/m9.figshare.21814623
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Ffeil
Toriadau
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Aberystwyth University Researchers Reveal New Findings on Nucleoproteins [Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes [version 1; peer review: 2 approved]]
10 Awst 2023
1 eitem o Sylw ar y cyfryngau
Y Wasg / Cyfryngau: Sylw yn y cyfryngau