Karl Hoffmann

2024

Compounds Containing 2,3-Bis(phenylamino) Quinoxaline Exhibit Activity Against Methicillin-Resistant Staphylococcus aureus, Enterococcus faecalis, and Their Biofilms

Padalino, G., Duggan, K., Mur, L. A. J., Maillard, J.-Y., Brancale, A. & Hoffmann, K. F., 01 Rhag 2024, Yn: MicrobiologyOpen. 13, 6, e011.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Sylwadau/Trafodaethau

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Gut microbiota and immune profiling of microbiota-humanised versus wildtype mouse models of hepatointestinal schistosomiasis

Stark, K. A., Rinaldi, G., Costain, A., Clare, S., Tolley, C., Almeida, A., McCarthy, C., Harcourt, K., Brandt, C., Lawley, T. D., Berriman, M., MacDonald, A. S., Forde-Thomas, J. E., Hulme, B. J., Hoffmann, K. F., Cantacessi, C. & Cortés, A., 01 Rhag 2024, Yn: Animal Microbiome. 6, 1, 36.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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1 Dyfyniad (Scopus)

2 Wedi eu Llwytho i Lawr (Pure)

Quinoxaline-Based Anti-Schistosomal Compounds Have Potent Anti-Malarial Activity

Rawat, M., Padalino, G., Yeo, T., Brancale, A., Fidock, D. A., Hoffmann, K. F. & Lee, M. C. S., 24 Ebr 2024, bioRxiv.

Allbwn ymchwil: Papur gweithio › Rhagargraffiad

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6 Wedi eu Llwytho i Lawr (Pure)

2023

Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes

Padalino, G., Celatka, C., Rienhoff Jr., H. Y., Kalin, J. H., Cole, P. A., Lassalle, D., Forde-Thomas, J., Chalmers, I., Brancale, A., Grunau, C. & Hoffmann, K., 30 Maw 2023, Yn: Wellcome Open Research. 8, 146, 29 t., 146.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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1 Dyfyniad (Scopus)

49 Wedi eu Llwytho i Lawr (Pure)

Modified Hederagenin Derivatives Demonstrate Ex Vivo Anthelmintic Activity against Fasciola hepatica

Chakroborty, A., Pritchard, D., Bouillon, M. E., Cervi, A., Kraehenbuehl, R., Wild, C., Fenn, C., Holdsworth, P. A., Capner, C., Padalino, G., Forde-Thomas, J., Payne, J., Smith, B. G., Fisher, M., Lahmann, M., Baird, M. S. & Hoffmann, K., 03 Gorff 2023, Yn: Pharmaceutics. 15, 7, 15 t., 1869.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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1 Dyfyniad (Scopus)

49 Wedi eu Llwytho i Lawr (Pure)

Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022

Caldwell, N., Afshar, R., Baragaña, B., Bustinduy, A. L., Caffrey, C. R., Collins, J. J., Fusco, D., Garba, A., Gardner, M., Gomes, M., Hoffmann, K. F., Hsieh, M., Lo, N. C., McNamara, C. W., Nono, J. K., Padalino, G., Read, K. D., Roestenberg, M., Spangenberg, T. & Specht, S. & 1 eraill, Gilbert, I. H., 12 Mai 2023, Yn: ACS Infectious Diseases. 9, 5, t. 1046-1055 10 t.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl Adolygu › adolygiad gan gymheiriaid

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14 Dyfyniadau (Scopus)

63 Wedi eu Llwytho i Lawr (Pure)

Pulmonary inflammation promoted by type-2 dendritic cells is a feature of human and murine schistosomiasis

Houlder, E. L., Costain, A. H., Nambuya, I., Brown, S. L., Koopman, J. P. R., Langenberg, M. C. C., Janse, J. J., Hoogerwerf, M. A., Ridley, A. J. L., Forde-Thomas, J. E., Colombo, S. A. P., Winkel, B. M. F., Galdon, A. A., Hoffmann, K. F., Cook, P. C., Roestenberg, M., Mpairwe, H. & MacDonald, A. S., 01 Rhag 2023, Yn: Nature Communications. 14, 1, 12 t., 1863.

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6 Dyfyniadau (Scopus)

126 Wedi eu Llwytho i Lawr (Pure)

Small Molecule Ligands of the BET-like Bromodomain, SmBRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development

Schiedel, M., McArdle, D. J. B., Padalino, G., Chan, A. K. N., Forde-Thomas, J., McDonough, M., Whiteland, H., Beckmann, M., Cookson, R., Hoffmann, K. F. & Conway, S. J., 14 Rhag 2023, Yn: Journal of Medicinal Chemistry. 66, 23, t. 15801-15822 22 t.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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2 Dyfyniadau (Scopus)

Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility

White, R., Sotillo, J., Ancarola, M. E., Borup, A., Boysen, A. T., Brindley, P. J., Buzás, E. I., Cavallero, S., Chaiyadet, S., Chalmers, I. W., Cucher, M. A., Dagenais, M., Davis, C. N., Devaney, E., Duque-Correa, M. A., Eichenberger, R. M., Fontenla, S., Gasan, T. A., Hokke, C. H. & Kosanovic, M. & 22 eraill, Kuipers, M. E., Laha, T., Loukas, A., Maizels, R. M., Marcilla, A., Mazanec, H., Morphew, R. M., Neophytou, K., Nguyen, L. T., Nolte-'t Hoen, E., Povelones, M., Robinson, M. W., Rojas, A., Schabussova, I., Smits, H. H., Sungpradit, S., Tritten, L., Whitehead, B., Zakeri, A., Nejsum, P., Buck, A. H. & Hoffmann, K. F., 05 Ion 2023, Yn: Journal of Extracellular Vesicles. 12, 1, 16 t., 12298.

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25 Dyfyniadau (Scopus)

83 Wedi eu Llwytho i Lawr (Pure)

Using ChEMBL to Complement Schistosome Drug Discovery

Padalino, G., Coghlan, A., Pagliuca, G., Forde-Thomas, J., Berriman, M. & Hoffmann, K., 28 Ebr 2023, Yn: Pharmaceutics. 15, 5, 26 t., 1359.

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4 Dyfyniadau (Scopus)

34 Wedi eu Llwytho i Lawr (Pure)

2022

Flukicidal effects of abietane diterpenoid derived analogues against the food borne pathogen Fasciola hepatica.

Chakroborty, A., Pritchard, D., Bouillon, M. E., Cervi, A., Cookson, A., Wild, C., Fenn, C., Payne, J., Holdsworth, P., Capner, C., O'Neill, J., Padalino, G., Forde-Thomas, J., Gupta, S., Smith, B. G., Fisher, M., Lahmann, M., Baird, M. S. & Hoffmann, K. F., 01 Medi 2022, Yn: Veterinary Parasitology. 309, 9 t., 109766.

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2 Dyfyniadau (Scopus)

85 Wedi eu Llwytho i Lawr (Pure)

Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production

Hulme, B. J., Geyer, K. K., Forde-Thomas, J. E., Padalino, G., Phillips, D. W., Ittiprasert, W., Karinshak, S. E., Mann, V. H., Chalmers, I. W., Brindley, P. J., Hokke, C. H. & Hoffmann, K. F., 13 Ion 2022, Yn: PLoS Pathogens. 18, 1, 35 t., e1009828.

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19 Dyfyniadau (Scopus)

118 Wedi eu Llwytho i Lawr (Pure)

2021

Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation

Padalino, G., El-Sakkary, N., Liu, L. J., Liu, C., Harte, D. S. G., Barnes, R. E., Sayers, E., Forde-Thomas, J., Whiteland, H., Bassetto, M., Ferla, S., Johnson, G., Jones, A. T., Caffrey, C. R., Chalmers, I., Brancale, A. & Hoffmann, K. F., 15 Rhag 2021, Yn: European Journal of Medicinal Chemistry. 226, 19 t., 113823.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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9 Dyfyniadau (Scopus)

152 Wedi eu Llwytho i Lawr (Pure)

Daily rhythms in gene expression of the human parasite Schistosoma mansoni

Rawlinson, K. A., Reid, A. J., Lu, Z., Driguez, P., Wawer, A., Coghlan, A., Sankaranarayanan, G., Buddenborg, S. K., Soria, C. D., McCarthy, C., Holroyd, N., Sanders, M., Hoffmann, K. F., Wilcockson, D., Rinaldi, G. & Berriman, M., 02 Rhag 2021, Yn: BMC Biology. 19, 1, t. 255 255.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

10 Dyfyniadau (Scopus)

Identifying and validating the presence of Guanine-Quadruplexes (G4) within the blood fluke parasite Schistosoma mansoni

Craven, H., Bonsignore, R., Lenis, V., Santi, N., Berrar, D., Swain, M., Whiteland, H., Casini, A. & Hoffmann, K., 18 Chwef 2021, Yn: PLoS Neglected Tropical Diseases. 15, 2, 24 t., e0008770.

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6 Dyfyniadau (Scopus)

138 Wedi eu Llwytho i Lawr (Pure)

Plasmacytoid Dendritic Cells Facilitate Th Cell Cytokine Responses throughout Schistosoma mansoni Infection

Webb, L. M., Phythian-Adams, A. T., Costain, A. H., Brown, S. L., Lundie, R. J., Forde-Thomas, J., Cook, P. C., Jackson-Jones, L. H., Marley, A. K., Smits, H. H., Hoffmann, K. F., Tait Wojno, E. D. & MacDonald, A. S., 31 Awst 2021, Yn: ImmunoHorizons. 5, 8, t. 721-732 12 t.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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7 Dyfyniadau (Scopus)

Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae

Gasan, T. A., Kuipers, M. E., Roberts, G. H., Padalino, G., Forde-Thomas, J. E., Wilson, S., Wawrzyniak, J., Tukahebwa, E. M., Hoffmann, K. F. & Chalmers, I. W., 18 Tach 2021, Yn: PLoS Neglected Tropical Diseases. 15, 11, e0009981.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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6 Dyfyniadau (Scopus)

Schistosoma mansoni venom allergen-like protein 6 (SmVAL6) maintains tegumental barrier function

Perally, S., Geyer, K. K., Farani, P. S. G., Chalmers, I. W., Fernandez-Fuentes, N., Maskell, D. R., Hulme, B. J., Forde-Thomas, J., Phillips, D., Farias, L. P., Collins, J. J. & Hoffmann, K. F., 01 Maw 2021, Yn: International Journal for Parasitology. 51, 4, t. 251-261 11 t.

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6 Dyfyniadau (Scopus)

94 Wedi eu Llwytho i Lawr (Pure)

Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni

Partridge, F. A., Bataille, C. J. R., Forman, R., Marriott, A. E., Forde-Thomas, J., Häberli, C., Dinsdale, R. L., O'Sullivan, J. D. B., Willis, N. J., Wynne, G. M., Whiteland, H., Archer, J., Steven, A., Keiser, J., Turner, J. D., Hoffmann, K. F., Taylor, M. J., Else, K. J., Russell, A. J. & Sattelle, D. B., 14 Mai 2021, Yn: ACS Infectious Diseases. 7, 5, t. 1260-1274 15 t.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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10 Dyfyniadau (Scopus)

440 Wedi eu Llwytho i Lawr (Pure)

2020

DC‐SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte‐derived dendritic cells

Kuipers, M. E., Nolte-‘t Hoen, E. N. M., van der Ham, A. J., Ozir-Fazalalikhan, A., Nguyen, D. L., de Korne, C. M., Koning, R. I., Tomes, J. J., Hoffmann, K. F., Smits, H. H. & Hokke, C. H., 01 Medi 2020, Yn: Journal of Extracellular Vesicles. 9, 1, 19 t., 1753420.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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49 Dyfyniadau (Scopus)

90 Wedi eu Llwytho i Lawr (Pure)

Helminth extracellular vesicles: Great balls of wonder

Hoffmann, K. F., Hokke, C. H., Loukas, A. & Buck, A. H., 05 Awst 2020, Yn: International Journal for Parasitology. 50, 9, t. 621-622 2 t.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl olygyddol

6 Dyfyniadau (Scopus)

Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities

Padalino, G., Chalmers, I. W., Brancale, A. & Hoffmann, K. F., 13 Tach 2020, Yn: Wellcome Open Research. 5, 37 t., 169.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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6 Dyfyniadau (Scopus)

71 Wedi eu Llwytho i Lawr (Pure)

Large-scale RNAi screening uncovers therapeutic targets in the parasite Schistosoma mansoni

Wang, J., Paz, C., Padalino, G., Coghlan, A., Lu, Z., Gradinaru, I., Collins, J. N. R., Berriman, M., Hoffmann, K. F. & Collins, J. J., 25 Medi 2020, Yn: Science (New York, N.Y.). 369, 6511, t. 1649-1653 5 t., eabb7699.

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55 Dyfyniadau (Scopus)

219 Wedi eu Llwytho i Lawr (Pure)

Quorum sensing N-Acyl homoserine lactones are a new class of anti-schistosomal

Whiteland, H., Crusco, A., Bloemberg, L. W., Tibble-Howlings, J., Forde-Thomas, J., Coghlan, A., Murphy, P. J. & Hoffmann, K. F., 19 Hyd 2020, Yn: PLoS Neglected Tropical Diseases. 14, 10, 22 t., e0008630.

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5 Dyfyniadau (Scopus)

211 Wedi eu Llwytho i Lawr (Pure)

The synthesis and glycosidase inhibitory activity of analogues of tiruchanduramine

Ashworth, Z. J. R., Bartholomew, B., Evans, D. M., Forde-Thomas, J., Hoffmann, K. F., Murdoch, R., Nash, R. J., Sharp, H., Whiteland, H. & Murphy, P. J., 19 Maw 2020, Yn: Heterocycles. 100, 4, t. 609-621 13 t.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

3 Dyfyniadau (Scopus)

2019

Antischistosomal Properties of Sclareol and Its Heck-Coupled Derivatives: Design, Synthesis, Biological Evaluation and Untargeted Metabolomics

Crusco, A., Whiteland, H., Baptista, R., Forde-Thomas, J. E., Beckmann, M., Mur, L. A. J., Nash, R. J., Westwell, A. D. & Hoffmann, K. F., 12 Gorff 2019, Yn: ACS Infectious Diseases. 5, 7, t. 1188-1199 12 t.

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27 Dyfyniadau (Scopus)

497 Wedi eu Llwytho i Lawr (Pure)

Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni

Wannaporn, I., Mann, V., Karinshak, S., Coghlan, A., Rinaldi, G., Sankaranarayanan, G., Chaidee, A., Tanno, T., Kumkhaek, C., Prangtaworn, P., Mentink-Kane, M. M., Cochran, C. J., Driguez, P., Holroyd, N., Tracey, A., Rodpai, R., Everts, B., Hokke, C. H., Hoffmann, K. & Berriman, M. & 1 eraill, Brindley, P. J., 15 Ion 2019, Yn: eLife. 8, N/A, 27 t., e41337.

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76 Dyfyniadau (Scopus)

212 Wedi eu Llwytho i Lawr (Pure)

Schistosoma mansoni venom allergen-like proteins: Phylogenetic relationships, stage-specific transcription and tissue localization as predictors of immunological cross-reactivity

Farias, L. P., Chalmers, I. W., Perally, S., Rofatto, H. K., Jackson, C. J., Brown, M., Khouri, M. I., Barbosa, M. M. F., Hensbergen, P. J., Hokke, C. H., Leite, L. C. C. & Hoffmann, K. F., 01 Gorff 2019, Yn: International Journal for Parasitology. 49, 8, t. 593-599 7 t.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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8 Dyfyniadau (Scopus)

168 Wedi eu Llwytho i Lawr (Pure)

The anti-mycobacterial activity of a diterpenoid-like molecule operates through nitrogen and amino acid starvation

Crusco, A., Alves Baptista, R., Bhowmick, S., Beckmann, M., Mur, L., Westwell, A. D. & Hoffmann, K., 25 Meh 2019, Yn: Frontiers in Microbiology. 10, JUN, 1444.

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1 Dyfyniad (Scopus)

201 Wedi eu Llwytho i Lawr (Pure)

The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets

Whatley, K., Padalino, G., Whiteland, H., Geyer, K. K., Hulme, B. J., Chalmers, I., Forde-Thomas, J., Ferla, S., Brancale, A. & Hoffmann, K., 15 Tach 2019, Yn: PLoS Neglected Tropical Diseases. 13, 11, 24 t., e0007693.

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21 Dyfyniadau (Scopus)

225 Wedi eu Llwytho i Lawr (Pure)

2018

An Abeis procera-derived tetracyclic triterpene containing a steroid-like nucleus core and a lactone side chain attenuates in vitro survival of both Fasciola hepatica and Schistosoma mansoni

Whiteland, H., Chakroborty, A., Forde-Thomas, J., Crusco, A., Cookson, A., Hollinshead, J., Fenn, C., Bartholomew, B., Holdsworth, P. A., Fisher, M., Nash, R. J. & Hoffmann, K., 01 Rhag 2018, Yn: International Journal for Parasitology: Drugs and Drug Resistance. 8, 3, t. 465-474 10 t.

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26 Dyfyniadau (Scopus)

166 Wedi eu Llwytho i Lawr (Pure)

Antibody Responses to Schistosoma mansoni Schistosomula Antigens

Egesa, M., Lubyayi, L., Jones, F. M., van Diepen, A., Chalmers, I., Tukahebwa, E. M., Bagaya, B. S., Hokke, C. H., Hoffmann, K., Dunne, D. W., Elliot, A. M., Yazdanbakhsh, M., Wilson, S. & Cose, S., 28 Tach 2018, Yn: Parasite Immunology. 40, 12, e12591.

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7 Dyfyniadau (Scopus)

156 Wedi eu Llwytho i Lawr (Pure)

Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni

Padalino, G., Ferla, S., Brancale, A., Chalmers, I. & Hoffmann, K., 31 Rhag 2018, Yn: International Journal for Parasitology: Drugs and Drug Resistance. 8, 3, t. 559-570 12 t.

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27 Dyfyniadau (Scopus)

184 Wedi eu Llwytho i Lawr (Pure)

Design, synthesis and anthelmintic activity of 7-keto-sempervirol analogues

Crusco, A., Bordoni, C., Chakroborty, A., Whatley, K. C. L., Whiteland, H., Westwell, A. D. & Hoffmann, K., 25 Mai 2018, Yn: European Journal of Medicinal Chemistry. 152, N/A, t. 87-100 14 t.

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29 Dyfyniadau (Scopus)

188 Wedi eu Llwytho i Lawr (Pure)

Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni

Roquis, D., Taudt, A., Geyer, K., Padalino, G., Hoffmann, K., Holroyd, N., Berriman, M., Allaga, B., Chaparro, C., Grunau, C. & de Carvalho Augusto, R., 21 Mai 2018, Yn: PLoS Pathogens. 14, 5, 26 t., e1007066.

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36 Dyfyniadau (Scopus)

177 Wedi eu Llwytho i Lawr (Pure)

Methyl-CpG-binding (SmMBD2/3) and chromobox (SmCBX) proteins are required for neoblast proliferation and oviposition in the parasitic blood fluke Schistosoma mansoni

Geyer, K., Munshi, S. E., Whiteland, H., Fernandez-Fuentes, N., Phillips, D. & Hoffmann, K., 28 Meh 2018, Yn: PLoS Pathogens. 14, 6, e1007107.

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12 Dyfyniadau (Scopus)

209 Wedi eu Llwytho i Lawr (Pure)

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Théry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin-Smith, G. K., Ayre, D. C., Bach, J. M., Bachurski, D., Baharvand, H., Balaj, L., Baldacchino, S., Bauer, N. N., Baxter, A. A., Bebawy, M. & Beckham, C. & 362 eraill, Bedina Zavec, A., Benmoussa, A., Berardi, A. C., Bergese, P., Bielska, E., Blenkiron, C., Bobis-Wozowicz, S., Boilard, E., Boireau, W., Bongiovanni, A., Borràs, F. E., Bosch, S., Boulanger, C. M., Breakefield, X., Breglio, A. M., Brennan, M., Brigstock, D. R., Brisson, A., Broekman, M. L. D., Bromberg, J. F., Bryl-Górecka, P., Buch, S., Buck, A. H., Burger, D., Busatto, S., Buschmann, D., Bussolati, B., Buzás, E. I., Byrd, J. B., Camussi, G., Carter, D. R. F., Caruso, S., Chamley, L. W., Chang, Y. T., Chaudhuri, A. D., Chen, C., Chen, S., Cheng, L., Chin, A. R., Clayton, A., Clerici, S. P., Cocks, A., Cocucci, E., Coffey, R. J., Cordeiro-da-Silva, A., Couch, Y., Coumans, F. A. W., Coyle, B., Crescitelli, R., Criado, M. F., D’Souza-Schorey, C., Das, S., de Candia, P., De Santana, E. F., De Wever, O., del Portillo, H. A., Demaret, T., Deville, S., Devitt, A., Dhondt, B., Di Vizio, D., Dieterich, L. C., Dolo, V., Dominguez Rubio, A. P., Dominici, M., Dourado, M. R., Driedonks, T. A. P., Duarte, F. V., Duncan, H. M., Eichenberger, R. M., Ekström, K., EL Andaloussi, S., Elie-Caille, C., Erdbrügger, U., Falcón-Pérez, J. M., Fatima, F., Fish, J. E., Flores-Bellver, M., Försönits, A., Frelet-Barrand, A., Fricke, F., Fuhrmann, G., Gabrielsson, S., Gámez-Valero, A., Gardiner, C., Gärtner, K., Gaudin, R., Gho, Y. S., Giebel, B., Gilbert, C., Gimona, M., Giusti, I., Goberdhan, D. C. I., Görgens, A., Gorski, S. M., Greening, D. W., Gross, J. C., Gualerzi, A., Gupta, G. N., Gustafson, D., Handberg, A., Haraszti, R. A., Harrison, P., Hegyesi, H., Hendrix, A., Hill, A. F., Hochberg, F. H., Hoffmann, K. F., Holder, B., Holthofer, H., Hosseinkhani, B., Hu, G., Huang, Y., Huber, V., Hunt, S., Ibrahim, A. G. E., Ikezu, T., Inal, J. M., Isin, M., Ivanova, A., Jackson, H. K., Jacobsen, S., Jay, S. M., Jayachandran, M., Jenster, G., Jiang, L., Johnson, S. M., Jones, J. C., Jong, A., Jovanovic-Talisman, T., Jung, S., Kalluri, R., Kano, S. I., Kaur, S., Kawamura, Y., Keller, E. T., Khamari, D., Khomyakova, E., Khvorova, A., Kierulf, P., Kim, K. P., Kislinger, T., Klingeborn, M., Klinke, D. J., Kornek, M., Kosanović, M. M., Kovács, Á. F., Krämer-Albers, E. M., Krasemann, S., Krause, M., Kurochkin, I. V., Kusuma, G. D., Kuypers, S., Laitinen, S., Langevin, S. M., Languino, L. R., Lannigan, J., Lässer, C., Laurent, L. C., Lavieu, G., Lázaro-Ibáñez, E., Le Lay, S., Lee, M. S., Lee, Y. X. F., Lemos, D. S., Lenassi, M., Leszczynska, A., Li, I. T. S., Liao, K., Libregts, S. F., Ligeti, E., Lim, R., Lim, S. K., Linē, A., Linnemannstöns, K., Llorente, A., Lombard, C. A., Lorenowicz, M. J., Lörincz, Á. M., Lötvall, J., Lovett, J., Lowry, M. C., Loyer, X., Lu, Q., Lukomska, B., Lunavat, T. R., Maas, S. L. N., Malhi, H., Marcilla, A., Mariani, J., Mariscal, J., Martens-Uzunova, E. S., Martin-Jaular, L., Martinez, M. C., Martins, V. R., Mathieu, M., Mathivanan, S., Maugeri, M., McGinnis, L. K., McVey, M. J., Meckes, D. G., Meehan, K. L., Mertens, I., Minciacchi, V. R., Möller, A., Møller Jørgensen, M., Morales-Kastresana, A., Morhayim, J., Mullier, F., Muraca, M., Musante, L., Mussack, V., Muth, D. C., Myburgh, K. H., Najrana, T., Nawaz, M., Nazarenko, I., Nejsum, P., Neri, C., Neri, T., Nieuwland, R., Nimrichter, L., Nolan, J. P., Nolte-’t Hoen, E. N. M., Noren Hooten, N., O’Driscoll, L., O’Grady, T., O’Loghlen, A., Ochiya, T., Olivier, M., Ortiz, A., Ortiz, L. A., Osteikoetxea, X., Ostegaard, O., Ostrowski, M., Park, J., Pegtel, D. M., Peinado, H., Perut, F., Pfaffl, M. W., Phinney, D. G., Pieters, B. C. H., Pink, R. C., Pisetsky, D. S., Pogge von Strandmann, E., Polakovicova, I., Poon, I. K. H., Powell, B. H., Prada, I., Pulliam, L., Quesenberry, P., Radeghieri, A., Raffai, R. L., Raimondo, S., Rak, J., Ramirez, M. I., Raposo, G., Rayyan, M. S., Regev-Rudzki, N., Ricklefs, F. L., Robbins, P. D., Roberts, D. D., Rodrigues, S. C., Rohde, E., Rome, S., Rouschop, K. M. A., Rughetti, A., Russell, A. E., Saá, P., Sahoo, S., Salas-Huenuleo, E., Sánchez, C., Saugstad, J. A., Saul, M. J., Schiffelers, R. M., Schneider, R., Schøyen, T. H., Scott, A., Shahaj, E., Sharma, S., Shatnyeva, O., Shekari, F., Shelke, G. V., Shetty, A. K., Shiba, K., Siljander, P. R. M., Silva, A. M., Skowronek, A., Snyder, O. L., Soares, R. P., Sódar, B. W., Soekmadji, C., Sotillo, J., Stahl, P. D., Stoorvogel, W., Stott, S. L., Strasser, E. F., Swift, S., Tahara, H., Tewari, M., Timms, K., Tiwari, S., Tixeira, R., Tkach, M., Toh, W. S., Tomasini, R., Torrecilhas, A. C., Tosar, J. P., Toxavidis, V., Urbanelli, L., Vader, P., van Balkom, B. W. M., van der Grein, S. G., Van Deun, J., van Herwijnen, M. J. C., Van Keuren-Jensen, K., van Niel, G., van Royen, M. E., van Wijnen, A. J., Vasconcelos, M. H., Vechetti, I. J., Veit, T. D., Vella, L. J., Velot, É., Verweij, F. J., Vestad, B., Viñas, J. L., Visnovitz, T., Vukman, K. V., Wahlgren, J., Watson, D. C., Wauben, M. H. M., Weaver, A., Webber, J. P., Weber, V., Wehman, A. M., Weiss, D. J., Welsh, J. A., Wendt, S., Wheelock, A. M., Wiener, Z., Witte, L., Wolfram, J., Xagorari, A., Xander, P., Xu, J., Yan, X., Yáñez-Mó, M., Yin, H., Yuana, Y., Zappulli, V., Zarubova, J., Žėkas, V., Zhang, J. Y., Zhao, Z., Zheng, L., Zheutlin, A. R., Zickler, A. M., Zimmermann, P., Zivkovic, A. M., Zocco, D. & Zuba-Surma, E. K., 01 Ion 2018, Yn: Journal of Extracellular Vesicles. 7, 1, 1535750.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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7559 Dyfyniadau (Scopus)

Schistosoma mansoni schistosomula antigens induce Th1/Pro-inflammatory cytokine responses

Egesa, M., Lubyayi, L., Tukahebwa, E. M., Bagaya, B. S., Chalmers, I., Wilson, S., Hokke, C. H., Hoffmann, K., Dunne, D. W., Yazdanbakhsh, M., Labuda, L. A. & Cose, S., 28 Tach 2018, Yn: Parasite Immunology. 40, 12, e12592.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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17 Dyfyniadau (Scopus)

137 Wedi eu Llwytho i Lawr (Pure)

The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities

Geyer, K., Munshi, S. E., Vickers, M., Squance, M., Wilkinson, T., Berrar, D., Chaparro, C., Swain, M. & Hoffmann, K., 01 Awst 2018, Yn: International Journal for Parasitology: Drugs and Drug Resistance. 8, 2, t. 213-222 10 t.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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17 Dyfyniadau (Scopus)

206 Wedi eu Llwytho i Lawr (Pure)

2017

(Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach

Cosseau, C., Wolkenhauer, O., Padalino, G., Geyer, K., Hoffmann, K. & Grunau, C., 01 Ebr 2017, Yn: Trends in Parasitology. 33, 4, t. 285-294 10 t.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl Adolygu › adolygiad gan gymheiriaid

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27 Dyfyniadau (Scopus)

209 Wedi eu Llwytho i Lawr (Pure)

Neoclerodane Diterpenoids from Reehal Fatima, Teucrium yemense

Nur-e-Alam, M., Yousaf, M., Ahmed, S., Al-Sheddi, E. S., Shah, I., Fazakerley, D., Bari, A., Ghabbour, H. A., Threadgill, M. D., Whatley, K., Hoffmann, K. & Al-Rehaily, A. J., 23 Meh 2017, Yn: Journal of Natural Products. 80, 6, t. 1900-1908 9 t.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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15 Dyfyniadau (Scopus)

266 Wedi eu Llwytho i Lawr (Pure)

Rethinking Schistosomiasis Vaccine Development: Synthetic Vesicles

Egesa, M., Hoffmann, K., Hokke, C. H., Yazdanbakhsh, M. & Cose, S., 01 Rhag 2017, Yn: Trends in Parasitology. 33, 12, t. 918-921 4 t., 1671.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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15 Dyfyniadau (Scopus)

259 Wedi eu Llwytho i Lawr (Pure)

The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni

Geyer, K., Niazi, U., Duval, D., Cosseau, C., Tomlinson, C., Chalmers, I., Swain, M., Cutress, D., Bickham-Wright, U., Munshi, S. E., Grunau, C., Yoshino, T. P. & Hoffmann, K., 16 Mai 2017, Yn: PLoS Neglected Tropical Diseases. 11, 5, 29 t., e0005246.

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35 Dyfyniadau (Scopus)

210 Wedi eu Llwytho i Lawr (Pure)

Whole genome analysis of a schistosomiasis-transmitting freshwater snail

Adema, C. M., Hillier, L. W., Jones, C. S., Loker, E. S., Knight, M., Minx, P., Oliveira, G., Raghavan, N., Shedlock, A., do Amaral, L. R., Arican-Goktas, H. D., Assis, J. G., Baba, E. H., Baron, O. L., Bayne, C. J., Bickham-Wright, U., Biggar, K. K., Blouin, M., Bonning, B. C. & Botka, C. & 97 eraill, Bridger, J. M., Buckley, K. M., Buddenborg, S. K., Lima Caldeira, R., Carleton, J., Carvalho, O. S., Castillo, M. G., Chalmers, I. W., Christensens, M., Clifton, S., Cosseau, C., Coustau, C., Cripps, R. M., Cuesta-Astroz, Y., Cummins, S. F., Di Stephano, L., Dinguirard, N., Duval, D., Emrich, S., Feschotte, C., Feyereisen, R., Fitzgerald, P., Fronick, C., Fulton, L., Galinier, R., Gava, S. G., Geusz, M., Geyer, K. K., Giraldo-Calderón, G. I., de Souza Gomes, M., Gordy, M. A., Gourbal, B., Grunau, C., Hanington, P. C., Hoffmann, K. F., Hughes, D., Humphries, J., Jackson, D. J., Jannotti-Passos, L. K., De Jesus Jeremias, W., Jobling, S., Kamel, B., Kapusta, A., Kaur, S., Koene, J. M., Kohn, A. B., Lawson, D., Lawton, S. P., Liang, D., Limpanont, Y., Liu, S., Lockyer, A. E., Lovato, T. L., Ludolf, F., Magrini, V., Mcmanus, D. P., Medina, M., Misra, M., Mitta, G., Mkoji, G. M., Montague, M. J., Montelongo, C., Moroz, L. L., Munoz-Torres, M. C., Niazi, U., Noble, L. R., Oliveira, F. S., Pais, F. S., Papenfuss, A. T., Peace, R., Pena, J. J., Pila, E. A., Quelais, T., Raney, B. J., Rast, J. P., Rollinson, D., Rosse, I. C., Rotgans, B., Routledge, E. J., Ryan, K. M., Scholte, L. L. S., Storey, K. B., Swain, M., Tennessen, J. A., Tomlinson, C., Trujillo, D. L., Volpi, E. V., Walker, A. J., Wang, T., Wannaporn, I., Warren, W. C., Wu, X.-J., Yoshino, T. P., Yusuf, M., Zhang, S.-M., Zhao, M. & Wilson, R. K., 16 Mai 2017, Yn: Nature Communications. 8, t. 15451 15451.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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196 Dyfyniadau (Scopus)

170 Wedi eu Llwytho i Lawr (Pure)

2016

DISMISS: MeDIP-seq: High-throughput sequencing

Niazi, U. (Datblygwr), Geyer, K. (Datblygwr), Vickers, M. (Datblygwr), Hoffmann, K. (Datblygwr) & Swain, M. (Datblygwr), 02 Awst 2016

Allbwn ymchwil: Ffurf annhestunol › Meddalwedd

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DISMISS: Detection of stranded methylation in MeDIP-Seq data

Niazi, U., Geyer, K. K., Vickers, M. J., Hoffmann, K. & Swain, M., 29 Gorff 2016, Yn: BMC Bioinformatics. 17, 1, 295.

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9 Dyfyniadau (Scopus)

156 Wedi eu Llwytho i Lawr (Pure)

2015

Drug-Induced Exposure of Schistosoma mansoni Antigens SmCD59a and SmKK7

Reimers, N., Homann, A., Höschler, B., Langhans, K., Wilson, R. A., Pierrot, C., Khalife, J., Grevelding, C. G., Chalmers, I. W., Yazdanbakhsh, M., Hoffmann, K. F., Hokke, C. H., Haas, H. & Schramm, G., 16 Maw 2015, Yn: PLoS Neglected Tropical Diseases. 9, 3, e0003593.

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26 Dyfyniadau (Scopus)

168 Wedi eu Llwytho i Lawr (Pure)

Glycomic analysis of life stages of the human parasite Schistosoma mansoni reveals developmental expression profiles of functional and antigenic glycan motifs

Smit, C. H., van Diepen, A., Nguyen, D. L., Wuhrer, M., Hoffmann, K. F., Deelder, A. M. & Hokke, C. H., 01 Gorff 2015, Yn: Molecular and Cellular Proteomics. 14, 7, t. 1750-1769 20 t.

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79 Dyfyniadau (Scopus)

157 Wedi eu Llwytho i Lawr (Pure)

Human IgG1 Responses to Surface Localised Schistosoma mansoni Ly6 Family Members Drop following Praziquantel Treatment

Chalmers, I. W., Fitzsimmons, C. M., Brown, M., Pierrot, C., Jones, F. M., Wawrzyniak, J. M., Fernandez-Fuentes, N., Tukahebwa, E. M., Dunne, D. W., Khalife, J. & Hoffmann, K. F., Gorff 2015, Yn: PLoS Neglected Tropical Diseases. 9, 7, t. e0003920 e0003920.

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14 Dyfyniadau (Scopus)

202 Wedi eu Llwytho i Lawr (Pure)

Protein and small non-coding RNA-enriched extracellular vesicles are released by the pathogenic blood fluke Schistosoma mansoni

Nowacki, F. C., Swain, M. T., Klychnikov, O. I., Niazi, U., Ivens, A., Quintana, J. F., Hensbergen, P. J., Hokke, C. H., Buck, A. H. & Hoffmann, K. F., 05 Hyd 2015, Yn: Journal of Extracellular Vesicles. 4, 1, 28665.

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136 Dyfyniadau (Scopus)

164 Wedi eu Llwytho i Lawr (Pure)

Karl Hoffmann

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