Allbwn Ymchwil fesul blwyddyn
Allbwn Ymchwil fesul blwyddyn
Proffil personol
Diddordebau ymchwil
Our laboratory studies post-exponential phase gene expression in several Gram-positive bacteria, including Bacillus and Clostridium. Recent work on dormancy in Micrococcus luteus led to the discovery of the Rpf family of bacterial growth factors found throughout the actinobacteria (e.g. mycobacteria, streptomycetes). We are currently exploring the mechanism of actions of these secreted bacterial growth factors and their potential applications for TB protection and therapy.
Arbenigedd sy’n gysylltiedig â NDC y CU
Yn 2015, cytunodd gwladwriaethau sy’n aelodau'r Cenhedloedd Unedig ar 17 o Nodau Datblygu Cynaliadwy (NDC) byd-eang i ddod â thlodi i ben, diogelu’r blaned a sicrhau ffyniant i bawb. Mae gwaith y person hwn yn cyfrannu at y NDC canlynol:
Ôl bys
Ewch i ganol y pynciau ymchwil lle mae Mike Young ar waith. Mae’r labelau pwnc hyn yn dod o waith y person hwn. Gyda’i gilydd maen nhw’n ffurfio ôl bys unigryw.
- 1 Proffiliau Tebyg
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A Tool for Multiple Targeted Genome Deletions that Is Precise, Scar-Free, and Suitable for Automation.
Aubrey, W., Riley, M., Young, M., King, R. D., Oliver, S. G. & Clare, A., 02 Rhag 2015, Yn: PLoS One. 10, 12, e0142494.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil212 Wedi eu Llwytho i Lawr (Pure) -
Surviving the heat: Heterogeneity of response in Saccharomyces cerevisiae provides insight into thermal damage to the membrane
Guyot, S., Gervais, P., Young, M., Winckler, P., Dumont, J. & Davey, H., 14 Mai 2015, Yn: Environmental Microbiology. 17, 8, t. 2982-2992 11 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil48 Dyfyniadau (Scopus)83 Wedi eu Llwytho i Lawr (Pure) -
Cyclic Amp-Dependent Resuscitation of Dormant Mycobacteria by Exogenous Free Fatty Acids
Shleeva, M., Goncharenko, A., Kudykina, Y., Young, D., Young, M., Kaprelyants, A. & Tailleux, L. (Golygydd), 23 Rhag 2013, Yn: PLoS One. 8, 12, e82914.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil54 Dyfyniadau (Scopus)317 Wedi eu Llwytho i Lawr (Pure) -
PD5: a general purpose library for primer design software
Riley, M. C., Aubrey, W., Young, M. & Clare, A., 21 Tach 2013, Yn: PLoS One. 8, 11, e80156.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil4 Dyfyniadau (Scopus)222 Wedi eu Llwytho i Lawr (Pure) -
Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds
Bilsland, E., Sparkes, A. C., Williams, K. S., Moss, H. J., de Clare, M., Pir, P., Rowland, J., Aubrey, W., Pateman, R., Young, M., Carrington, M., King, R. D. & Oliver, S. G., 27 Chwef 2013, Yn: Open Biology. 3, 2, 14 t., 120158.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil30 Dyfyniadau (Scopus)195 Wedi eu Llwytho i Lawr (Pure) -
Zero Forcing, Linear and Quantum Controllability for Systems Evolving on Networks
Burgarth, D., D'Alessandro, D., Hogben, L., Severini, S. & Young, M., Medi 2013, Yn: IEEE Transactions on Automatic Control. 58, 9, t. 2349-2354 6 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil53 Dyfyniadau (Scopus)193 Wedi eu Llwytho i Lawr (Pure) -
Multiple orphan histidine kinases interact directly with Spo0A to control the initiation of endospore formation in Clostridium acetobutylicum
Heap, J. P., Young, D. I., Dago, A. E., Minton, N. P., Hoch, J. A., Young, M. & Steiner, E., 14 Maw 2011, Yn: Molecular Microbiology. 80, 3, t. 641-654 14 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
116 Dyfyniadau (Scopus) -
Possible interactions between bacterial diversity, microbial activity and supraglacial hydrology of cryoconite holes in Svalbard
Edwards, A., Anesio, A. M., Edwards Rassner, S. M., Sattler, B., Hubbard, B. P., Perkins, W. T., Young, M. & Griffith, G. W., 01 Ion 2011, Yn: ISME Journal. 5, 1, t. 150-160 11 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Mynediad agoredFfeil149 Dyfyniadau (Scopus)101 Wedi eu Llwytho i Lawr (Pure) -
An Integrated Laboratory Robotic System for Autonomous Discovery of Gene Function
Sparkes, A. C., King, R. D., Aubrey, W., Benway, M., Byrne, E. L., Clare, A. J., Liakata, M., Markham, M., Whelan, K. E., Young, M. & Rowland, J., 01 Chwef 2010, Yn: Journal of The Association for Laboratory Automation. 15, 1, t. 33-40 8 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
3 Dyfyniadau (Scopus) -
Genome sequence of the Fleming strain of Micrococcus luteus, a simple free-living actinobacterium
Young, M., Artsatbanov, V., Beller, H. R., Chandra, G., Chater, K. F., Dover, L. G., Goh, E.-B., Kahan, T., Kaprelyants, A. S., Kyrpides, N., Lapidus, A., Lowry, S. R., Lykidis, A., Mahillon, J., Markowitz, V., Mavromatis, K., Mukamolova, G. V., Oren, A., Rokem, J. S. & Smith, M. C. M. & 2 eraill, , 01 Chwef 2010, Yn: Journal of Bacteriology. 192, 3, t. 841-860 20 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
60 Dyfyniadau (Scopus) -
Structural changes and cellular localization of resuscitation promoting factor in environmental isolates of Micrococcus luteus
Koltunov, V., Greenblatt, C. L., Goncharenko, A. V., Demina, G. R., Klein, B. Y., Young, M. & Kaprelyants, A. S., 01 Chwef 2010, Yn: Microbial Ecology. 59, 2, t. 296-310 15 t.Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
13 Dyfyniadau (Scopus)
Prosiectau
- 4 Wedi Gorffen
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Cleavage Specificityof the Rpf proteins
Young, M. (Prif Ymchwilydd)
01 Ebr 2011 → 31 Awst 2011
Prosiect: Ymchwil a ariannwyd yn allanol
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The roles of prokaryotic dormancy, resuscitation and survival in the ecology of human skin biofilms (CASE award)
Young, M. (Prif Ymchwilydd)
Unilever UK Central Resources Ltd
01 Rhag 2007 → 30 Tach 2010
Prosiect: Ymchwil a ariannwyd yn allanol
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CASE Studentship The roles of prokarvotic dormancy, recusitation and survival in the ecology of human skin biofilms
Young, M. (Prif Ymchwilydd)
Biotechnology and Biological Sciences Research Council
01 Hyd 2007 → 30 Medi 2011
Prosiect: Ymchwil a ariannwyd yn allanol
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Initiation of endospore formation in clostridia
Young, M. (Prif Ymchwilydd)
Biotechnology and Biological Sciences Research Council
01 Ion 2006 → 31 Rhag 2008
Prosiect: Ymchwil a ariannwyd yn allanol