Process improvement to enable economic production of prebiotics and demonstration of efficacy in feeding trials (PIPP)

Prosiect: Ymchwil a ariannwyd yn allanol

Manylion y Prosiect


Grass is a readily available feedstock for the production of prebiotics, a market worth $1.4 Billion. Grass juice fructans, converted to short chain molecules (SCM) by hydrolases, show prebiotic activity greater than commercial comparators (assessed using an artificial gut system). Market take-up is hampered by production cost and demonstration in animal systems. In this project the hydrolases will be cloned into a bacterium. This will greatly improve process economics and avoid the major cost of expensive enzymes. The SCMs produced will be used as feed supplements in mice trials. The prebiotic activity of these molecules will be assessed by examination of the mice microbiome using next generation sequencing. Additionally, economic viability, market opportunities, regulatory issues and supply chain logistics will also be determined ensuring a likely take-up of this technology in the market place.
StatwsWedi gorffen
Dyddiad cychwyn/gorffen dod i rym01 Maw 201730 Tach 2018


  • Biotechnology and Biological Sciences Research Council (BB/P004849/1): £194,262.84

Ôl bys

Archwilio’r pynciau ymchwil mae a wnelo'r prosiect hwn â nhw. Mae’r labelau hyn yn cael eu cynhyrchu’n seiliedig ar y dyfarniadau/grantiau sylfaenol. Gyda’i gilydd maen nhw’n ffurfio ôl bys unigryw.