A new diagnostic tool for neurocysticercosis is a member of a cestode specific hydrophobic ligand binding protein family

Nahid Saghir; Phillip J. Conde; Peter Brophy; John Barrett

doi:10.1016/S0014-5793(00)02191-8

A new diagnostic tool for neurocysticercosis is a member of a cestode specific hydrophobic ligand binding protein family

Nahid Saghir, Phillip J. Conde, Peter Brophy, John Barrett

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Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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A protein of unknown function has been identified as a key serological tool for diagnosis of human tapeworm neurocysticercosis, a major worldwide neurological disease. Our own sequence analysis predicts that this protein is a member of a newly identified cestode specific oligomeric hydrophobic ligand binding protein family. In this report, using a rat cestode model, we confirm that homologues of this protein can bind fatty acids and their derivatives, and thus suggest a biological function for this key diagnostic tool

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	181-184
Nifer y tudalennau	4
Cyfnodolyn	FEBS Letters
Cyfrol	487
Rhif cyhoeddi	2
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1016/S0014-5793(00)02191-8
Statws	Cyhoeddwyd - 29 Rhag 2000

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10.1016/S0014-5793(00)02191-8

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title = "A new diagnostic tool for neurocysticercosis is a member of a cestode specific hydrophobic ligand binding protein family",

abstract = "A protein of unknown function has been identified as a key serological tool for diagnosis of human tapeworm neurocysticercosis, a major worldwide neurological disease. Our own sequence analysis predicts that this protein is a member of a newly identified cestode specific oligomeric hydrophobic ligand binding protein family. In this report, using a rat cestode model, we confirm that homologues of this protein can bind fatty acids and their derivatives, and thus suggest a biological function for this key diagnostic tool",

keywords = "Cestoda, Diagnosis, Hydrophobic ligand binding protein, Hymenolepis diminuta",

author = "Nahid Saghir and Conde, {Phillip J.} and Peter Brophy and John Barrett",

year = "2000",

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day = "29",

doi = "10.1016/S0014-5793(00)02191-8",

language = "English",

volume = "487",

pages = "181--184",

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T1 - A new diagnostic tool for neurocysticercosis is a member of a cestode specific hydrophobic ligand binding protein family

AU - Saghir, Nahid

AU - Conde, Phillip J.

AU - Brophy, Peter

AU - Barrett, John

PY - 2000/12/29

Y1 - 2000/12/29

N2 - A protein of unknown function has been identified as a key serological tool for diagnosis of human tapeworm neurocysticercosis, a major worldwide neurological disease. Our own sequence analysis predicts that this protein is a member of a newly identified cestode specific oligomeric hydrophobic ligand binding protein family. In this report, using a rat cestode model, we confirm that homologues of this protein can bind fatty acids and their derivatives, and thus suggest a biological function for this key diagnostic tool

AB - A protein of unknown function has been identified as a key serological tool for diagnosis of human tapeworm neurocysticercosis, a major worldwide neurological disease. Our own sequence analysis predicts that this protein is a member of a newly identified cestode specific oligomeric hydrophobic ligand binding protein family. In this report, using a rat cestode model, we confirm that homologues of this protein can bind fatty acids and their derivatives, and thus suggest a biological function for this key diagnostic tool

KW - Cestoda

KW - Diagnosis

KW - Hydrophobic ligand binding protein

KW - Hymenolepis diminuta

UR - http://www.scopus.com/inward/record.url?scp=0034731315&partnerID=8YFLogxK

U2 - 10.1016/S0014-5793(00)02191-8

DO - 10.1016/S0014-5793(00)02191-8

M3 - Article

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VL - 487

SP - 181

EP - 184

JO - FEBS Letters

JF - FEBS Letters

IS - 2

ER -

A new diagnostic tool for neurocysticercosis is a member of a cestode specific hydrophobic ligand binding protein family

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Mynediad at Ddogfen

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