@inbook{00197776f0654de287f2cc0b51d5059b,
title = "Construction of high-resolution comparative maps in mammals using BAC-end sequences",
abstract = "Whole-genome bacterial artificial chromosome (BAC) libraries for ∼40 representative species of mammals provide unique resources for the construction of high-resolution ordered genomic maps, the development of species genetics, and multispecies genome comparisons. Herein we describe procedures to construct high-quality radiation hybrid comparative maps using BAC-end sequences (BESs). This approach has been applied to the construction of ∼1 Mbp resolution porcine-human and cattle-human comparative maps. High-resolution ordered comparative maps built with BESs and whole-genome sequences have been shown to be an invaluable resource for the analysis of mammalian chromosome evolution, and as a backbone for the assembly of whole-genome shotgun sequences.",
keywords = "BAC-end sequences, comparative mapping, genome analusis, radiation hybrid mapping",
author = "Denis Larkin and Harris Lewin",
year = "2008",
doi = "10.1007/978-1-59745-581-7_6",
language = "English",
series = "Methods in Molecular Biology",
publisher = "Springer Nature",
pages = "79--90",
editor = "Murphy, {William J.}",
booktitle = "Phylogenomics",
address = "Switzerland",
}