TY - JOUR
T1 - DAD-Net
T2 - Classification of Alzheimer’s Disease Using ADASYN Oversampling Technique and Optimized Neural Network
AU - Ahmed, Gulnaz
AU - Er, Meng Joo
AU - Fareed, Mian Muhammad Sadiq
AU - Zikria, Shahid
AU - Mahmood, Saqib
AU - He, Jiao
AU - Asad, Muhammad
AU - Jilani, Syeda Fizzah
AU - Aslam, Muhammad
N1 - Funding Information:
This research work was funded by ILMA University, under the ILMA Research Publication Grant ILMA/ORIC/RJ/2023/1001.
Publisher Copyright:
© 2022 by the authors.
PY - 2022/10/20
Y1 - 2022/10/20
N2 - Alzheimer’s Disease (AD) is a neurological brain disorder that causes dementia and neurological dysfunction, affecting memory, behavior, and cognition. Deep Learning (DL), a kind of Artificial Intelligence (AI), has paved the way for new AD detection and automation methods. The DL model’s prediction accuracy depends on the dataset’s size. The DL models lose their accuracy when the dataset has an imbalanced class problem. This study aims to use the deep Convolutional Neural Network (CNN) to develop a reliable and efficient method for identifying Alzheimer’s disease using MRI. In this study, we offer a new CNN architecture for diagnosing Alzheimer’s disease with a modest number of parameters, making it perfect for training a smaller dataset. This proposed model correctly separates the early stages of Alzheimer’s disease and displays class activation patterns on the brain as a heat map. The proposed Detection of Alzheimer’s Disease Network (DAD-Net) is developed from scratch to correctly classify the phases of Alzheimer’s disease while reducing parameters and computation costs. The Kaggle MRI image dataset has a severe problem with class imbalance. Therefore, we used a synthetic oversampling technique to distribute the image throughout the classes and avoid the problem. Precision, recall, F1-score, Area Under the Curve (AUC), and loss are all used to compare the proposed DAD-Net against DEMENET and CNN Model. For accuracy, AUC, F1-score, precision, and recall, the DAD-Net achieved the following values for evaluation metrics: 99.22%, 99.91%, 99.19%, 99.30%, and 99.14%, respectively. The presented DAD-Net outperforms other state-of-the-art models in all evaluation metrics, according to the simulation results.
AB - Alzheimer’s Disease (AD) is a neurological brain disorder that causes dementia and neurological dysfunction, affecting memory, behavior, and cognition. Deep Learning (DL), a kind of Artificial Intelligence (AI), has paved the way for new AD detection and automation methods. The DL model’s prediction accuracy depends on the dataset’s size. The DL models lose their accuracy when the dataset has an imbalanced class problem. This study aims to use the deep Convolutional Neural Network (CNN) to develop a reliable and efficient method for identifying Alzheimer’s disease using MRI. In this study, we offer a new CNN architecture for diagnosing Alzheimer’s disease with a modest number of parameters, making it perfect for training a smaller dataset. This proposed model correctly separates the early stages of Alzheimer’s disease and displays class activation patterns on the brain as a heat map. The proposed Detection of Alzheimer’s Disease Network (DAD-Net) is developed from scratch to correctly classify the phases of Alzheimer’s disease while reducing parameters and computation costs. The Kaggle MRI image dataset has a severe problem with class imbalance. Therefore, we used a synthetic oversampling technique to distribute the image throughout the classes and avoid the problem. Precision, recall, F1-score, Area Under the Curve (AUC), and loss are all used to compare the proposed DAD-Net against DEMENET and CNN Model. For accuracy, AUC, F1-score, precision, and recall, the DAD-Net achieved the following values for evaluation metrics: 99.22%, 99.91%, 99.19%, 99.30%, and 99.14%, respectively. The presented DAD-Net outperforms other state-of-the-art models in all evaluation metrics, according to the simulation results.
KW - ADASYN
KW - class activation
KW - computer-aided diagnosis
KW - Deep Learning
KW - image classification
KW - imbalanced data-set
KW - mri data-set
KW - supervised learning
KW - transfer learning
UR - http://www.scopus.com/inward/record.url?scp=85140776932&partnerID=8YFLogxK
U2 - 10.3390/molecules27207085
DO - 10.3390/molecules27207085
M3 - Article
C2 - 36296677
AN - SCOPUS:85140776932
SN - 1420-3049
VL - 27
JO - Molecules
JF - Molecules
IS - 20
M1 - 7085
ER -