Entity/quality-based logical definitions for the human skeletal phenome using PATO

Georgios V Gkoutos, Chris Mungall, Sandra Dolken, Michael Ashburner, Suzanna Lewis, John Hancock, Paul Schofield, Sebastian Kohler, Peter N Robinson

Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion CynhadleddTrafodion Cynhadledd (Nid-Cyfnodolyn fathau)

69 Dyfyniadau(SciVal)

Crynodeb

This paper describes an approach to providing computer-interpretable logical definitions for the terms of the Human Phenotype Ontology (HPO) using PATO, the ontology of phenotypic qualities, to link terms of the HPO to the anatomic and other entities that are affected by abnormal phenotypic qualities. This approach will allow improved computerized reasoning as well as a facility to compare phenotypes between different species. The PATO mapping will also provide direct links from phenotypic abnormalities and underlying anatomic structures encoded using the Foundational Model of Anatomy, which will be a valuable resource for computational investigations of the links between anatomical components and concepts representing diseases with abnormal phenotypes and associated genes.
Iaith wreiddiolSaesneg
TeitlEngineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
CyhoeddwrIEEE Press
Tudalennau7069-7072
Nifer y tudalennau4
ISBN (Electronig)978-1-4244-3296-7
ISBN (Argraffiad)978-1-4244-3296-7
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 2009
DigwyddiadAnnual International conference of the IEEE, Engineering in Medicine and Biology Society - , Teyrnas Unedig Prydain Fawr a Gogledd Iwerddon
Hyd: 03 Medi 200906 Medi 2009

Cynhadledd

CynhadleddAnnual International conference of the IEEE, Engineering in Medicine and Biology Society
Gwlad/TiriogaethTeyrnas Unedig Prydain Fawr a Gogledd Iwerddon
Cyfnod03 Medi 200906 Medi 2009

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