Entity/quality-based logical definitions for the human skeletal phenome using PATO

Georgios V Gkoutos; Chris Mungall; Sandra Dolken; Michael Ashburner; Suzanna Lewis; John Hancock; Paul Schofield; Sebastian Kohler; Peter N Robinson

doi:10.1109/IEMBS.2009.5333362

Entity/quality-based logical definitions for the human skeletal phenome using PATO

Georgios V Gkoutos
, Chris Mungall
, Sandra Dolken
, Michael Ashburner
, Suzanna Lewis
, John Hancock
, Paul Schofield
, Sebastian Kohler
, Peter N Robinson

Adran Cyfrifiadureg

Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion Cynhadledd › Trafodion Cynhadledd (ISBN)

71 Dyfyniadau (Scopus)

Crynodeb

This paper describes an approach to providing computer-interpretable logical definitions for the terms of the Human Phenotype Ontology (HPO) using PATO, the ontology of phenotypic qualities, to link terms of the HPO to the anatomic and other entities that are affected by abnormal phenotypic qualities. This approach will allow improved computerized reasoning as well as a facility to compare phenotypes between different species. The PATO mapping will also provide direct links from phenotypic abnormalities and underlying anatomic structures encoded using the Foundational Model of Anatomy, which will be a valuable resource for computational investigations of the links between anatomical components and concepts representing diseases with abnormal phenotypes and associated genes.

Iaith wreiddiol	Saesneg
Teitl	Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Cyhoeddwr	Institute of Electrical and Electronics Engineers
Tudalennau	7069-7072
Nifer y tudalennau	4
ISBN (Electronig)	978-1-4244-3296-7
ISBN (Argraffiad)	978-1-4244-3296-7
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1109/IEMBS.2009.5333362
Statws	Cyhoeddwyd - 2009
Digwyddiad	Annual International conference of the IEEE, Engineering in Medicine and Biology Society - , Teyrnas Unedig Prydain Fawr a Gogledd Iwerddon Hyd: 03 Medi 2009 → 06 Medi 2009

Cynhadledd

Cynhadledd	Annual International conference of the IEEE, Engineering in Medicine and Biology Society
Gwlad/Tiriogaeth	Teyrnas Unedig Prydain Fawr a Gogledd Iwerddon
Cyfnod	03 Medi 2009 → 06 Medi 2009

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10.1109/IEMBS.2009.5333362

Cysylltiad parhaol

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http://hdl.handle.net/2160/12088

Dyfynnu hyn

Gkoutos, G. V., Mungall, C., Dolken, S., Ashburner, M., Lewis, S., Hancock, J., Schofield, P., Kohler, S., & Robinson, P. N. (2009). Entity/quality-based logical definitions for the human skeletal phenome using PATO. Yn Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE (tt. 7069-7072). Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/IEMBS.2009.5333362

@inproceedings{ff0e6fdf36434887b3a1377e905157ae,

title = "Entity/quality-based logical definitions for the human skeletal phenome using PATO",

abstract = "This paper describes an approach to providing computer-interpretable logical definitions for the terms of the Human Phenotype Ontology (HPO) using PATO, the ontology of phenotypic qualities, to link terms of the HPO to the anatomic and other entities that are affected by abnormal phenotypic qualities. This approach will allow improved computerized reasoning as well as a facility to compare phenotypes between different species. The PATO mapping will also provide direct links from phenotypic abnormalities and underlying anatomic structures encoded using the Foundational Model of Anatomy, which will be a valuable resource for computational investigations of the links between anatomical components and concepts representing diseases with abnormal phenotypes and associated genes.",

author = "Gkoutos, \{Georgios V\} and Chris Mungall and Sandra Dolken and Michael Ashburner and Suzanna Lewis and John Hancock and Paul Schofield and Sebastian Kohler and Robinson, \{Peter N\}",

year = "2009",

doi = "10.1109/IEMBS.2009.5333362",

language = "English",

isbn = "978-1-4244-3296-7",

pages = "7069--7072",

booktitle = "Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE",

publisher = "Institute of Electrical and Electronics Engineers",

address = "United States of America",

note = "Annual International conference of the IEEE, Engineering in Medicine and Biology Society ; Conference date: 03-09-2009 Through 06-09-2009",

}

Gkoutos, GV, Mungall, C, Dolken, S, Ashburner, M, Lewis, S, Hancock, J, Schofield, P, Kohler, S & Robinson, PN 2009, Entity/quality-based logical definitions for the human skeletal phenome using PATO. yn Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE. Institute of Electrical and Electronics Engineers, tt. 7069-7072, Annual International conference of the IEEE, Engineering in Medicine and Biology Society, Teyrnas Unedig Prydain Fawr a Gogledd Iwerddon, 03 Medi 2009. https://doi.org/10.1109/IEMBS.2009.5333362

Entity/quality-based logical definitions for the human skeletal phenome using PATO. / Gkoutos, Georgios V; Mungall, Chris; Dolken, Sandra et al.
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE. Institute of Electrical and Electronics Engineers, 2009. t. 7069-7072.

Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion Cynhadledd › Trafodion Cynhadledd (ISBN)

TY - GEN

T1 - Entity/quality-based logical definitions for the human skeletal phenome using PATO

AU - Gkoutos, Georgios V

AU - Mungall, Chris

AU - Dolken, Sandra

AU - Ashburner, Michael

AU - Lewis, Suzanna

AU - Hancock, John

AU - Schofield, Paul

AU - Kohler, Sebastian

AU - Robinson, Peter N

PY - 2009

Y1 - 2009

N2 - This paper describes an approach to providing computer-interpretable logical definitions for the terms of the Human Phenotype Ontology (HPO) using PATO, the ontology of phenotypic qualities, to link terms of the HPO to the anatomic and other entities that are affected by abnormal phenotypic qualities. This approach will allow improved computerized reasoning as well as a facility to compare phenotypes between different species. The PATO mapping will also provide direct links from phenotypic abnormalities and underlying anatomic structures encoded using the Foundational Model of Anatomy, which will be a valuable resource for computational investigations of the links between anatomical components and concepts representing diseases with abnormal phenotypes and associated genes.

AB - This paper describes an approach to providing computer-interpretable logical definitions for the terms of the Human Phenotype Ontology (HPO) using PATO, the ontology of phenotypic qualities, to link terms of the HPO to the anatomic and other entities that are affected by abnormal phenotypic qualities. This approach will allow improved computerized reasoning as well as a facility to compare phenotypes between different species. The PATO mapping will also provide direct links from phenotypic abnormalities and underlying anatomic structures encoded using the Foundational Model of Anatomy, which will be a valuable resource for computational investigations of the links between anatomical components and concepts representing diseases with abnormal phenotypes and associated genes.

UR - http://hdl.handle.net/2160/12088

U2 - 10.1109/IEMBS.2009.5333362

DO - 10.1109/IEMBS.2009.5333362

M3 - Conference Proceeding (ISBN)

C2 - 19964203

SN - 978-1-4244-3296-7

SP - 7069

EP - 7072

BT - Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE

PB - Institute of Electrical and Electronics Engineers

T2 - Annual International conference of the IEEE, Engineering in Medicine and Biology Society

Y2 - 3 September 2009 through 6 September 2009

ER -

Entity/quality-based logical definitions for the human skeletal phenome using PATO

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