European 2 - A clonal complex of Mycobacterium bovis dominant in the Iberian Peninsula

Sabrina Rodriguez-Campos; Anita C. Schürch; James Dale; Amanda J. Lohan; Mónica V. Cunha; Ana Botelho; Krystel De Cruz; M. Laura Boschiroli; M. Beatrice Boniotti; Maria Pacciarini; M. Carmen Garcia-Pelayo; Beatriz Romero; Lucía de Juan; Lucas Domínguez; Stephen V. Gordon; Dick van Soolingen; Brendan Loftus; Stefan Berg; R. Glyn Hewinson; Alicia Aranaz; Noel H. Smith

doi:10.1016/j.meegid.2011.09.004

European 2 - A clonal complex of Mycobacterium bovis dominant in the Iberian Peninsula

Sabrina Rodriguez-Campos, Anita C. Schürch, James Dale, Amanda J. Lohan, Mónica V. Cunha, Ana Botelho, Krystel De Cruz, M. Laura Boschiroli, M. Beatrice Boniotti, Maria Pacciarini, M. Carmen Garcia-Pelayo, Beatriz Romero, Lucía de Juan, Lucas Domínguez, Stephen V. Gordon, Dick van Soolingen, Brendan Loftus, Stefan Berg, R. Glyn Hewinson, Alicia Aranaz^*Noel H. Smith

^*Awdur cyfatebol y gwaith hwn

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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Mycobacterium bovis isolates from the Iberian Peninsula are dominated by strains with spoligotype patterns deleted for spacer 21. Whole-genome sequencing of three Spanish strains with spacer 21 missing in their spoligotype pattern revealed a series of SNPs and subsequent screening of a selection of these SNPs identified one in gene guaA that is specific to these strains. This group of strains from the Iberian Peninsula missing spoligotype spacer 21 represents a new clonal complex of M. bovis, defined by the SNP profile with a distinct spoligotype signature. We have named this clonal complex European 2 (Eu2) and found that it was present at low frequency in both France and Italy and absent from the British Isles.

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	866-872
Nifer y tudalennau	7
Cyfnodolyn	Infection, Genetics and Evolution
Cyfrol	12
Rhif cyhoeddi	4
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1016/j.meegid.2011.09.004
Statws	Cyhoeddwyd - 01 Meh 2012

NDC y CU

Mae’r allbwn hwn yn cyfrannu at y Nod(au) Datblygu Cynaliadwy canlynol

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10.1016/j.meegid.2011.09.004

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Link to publication in Scopus

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Rodriguez-Campos, S., Schürch, A. C., Dale, J., Lohan, A. J., Cunha, M. V., Botelho, A., Cruz, K. D., Boschiroli, M. L., Boniotti, M. B., Pacciarini, M., Garcia-Pelayo, M. C., Romero, B., de Juan, L., Domínguez, L., Gordon, S. V., van Soolingen, D., Loftus, B., Berg, S., Hewinson, R. G., ... Smith, N. H. (2012). European 2 - A clonal complex of Mycobacterium bovis dominant in the Iberian Peninsula. Infection, Genetics and Evolution, 12(4), 866-872. https://doi.org/10.1016/j.meegid.2011.09.004

@article{b76219a186ff4faaaa1e0d40650ecdb4,

title = "European 2 - A clonal complex of Mycobacterium bovis dominant in the Iberian Peninsula",

abstract = "Mycobacterium bovis isolates from the Iberian Peninsula are dominated by strains with spoligotype patterns deleted for spacer 21. Whole-genome sequencing of three Spanish strains with spacer 21 missing in their spoligotype pattern revealed a series of SNPs and subsequent screening of a selection of these SNPs identified one in gene guaA that is specific to these strains. This group of strains from the Iberian Peninsula missing spoligotype spacer 21 represents a new clonal complex of M. bovis, defined by the SNP profile with a distinct spoligotype signature. We have named this clonal complex European 2 (Eu2) and found that it was present at low frequency in both France and Italy and absent from the British Isles.",

keywords = "Clonal complex, Europe, Mycobacterium bovis, Phylogeny, Whole genome sequencing",

author = "Sabrina Rodriguez-Campos and Sch{\"u}rch, {Anita C.} and James Dale and Lohan, {Amanda J.} and Cunha, {M{\'o}nica V.} and Ana Botelho and Cruz, {Krystel De} and Boschiroli, {M. Laura} and Boniotti, {M. Beatrice} and Maria Pacciarini and Garcia-Pelayo, {M. Carmen} and Beatriz Romero and {de Juan}, Luc{\'i}a and Lucas Dom{\'i}nguez and Gordon, {Stephen V.} and {van Soolingen}, Dick and Brendan Loftus and Stefan Berg and Hewinson, {R. Glyn} and Alicia Aranaz and Smith, {Noel H.}",

year = "2012",

month = jun,

day = "1",

doi = "10.1016/j.meegid.2011.09.004",

language = "English",

volume = "12",

pages = "866--872",

journal = "Infection, Genetics and Evolution",

issn = "1567-1348",

publisher = "Elsevier",

number = "4",

}

Rodriguez-Campos, S, Schürch, AC, Dale, J, Lohan, AJ, Cunha, MV, Botelho, A, Cruz, KD, Boschiroli, ML, Boniotti, MB, Pacciarini, M, Garcia-Pelayo, MC, Romero, B, de Juan, L, Domínguez, L, Gordon, SV, van Soolingen, D, Loftus, B, Berg, S, Hewinson, RG, Aranaz, A & Smith, NH 2012, 'European 2 - A clonal complex of Mycobacterium bovis dominant in the Iberian Peninsula', Infection, Genetics and Evolution, cyfrol. 12, rhif 4, tt. 866-872. https://doi.org/10.1016/j.meegid.2011.09.004

TY - JOUR

T1 - European 2 - A clonal complex of Mycobacterium bovis dominant in the Iberian Peninsula

AU - Rodriguez-Campos, Sabrina

AU - Schürch, Anita C.

AU - Dale, James

AU - Lohan, Amanda J.

AU - Cunha, Mónica V.

AU - Botelho, Ana

AU - Cruz, Krystel De

AU - Boschiroli, M. Laura

AU - Boniotti, M. Beatrice

AU - Pacciarini, Maria

AU - Garcia-Pelayo, M. Carmen

AU - Romero, Beatriz

AU - de Juan, Lucía

AU - Domínguez, Lucas

AU - Gordon, Stephen V.

AU - van Soolingen, Dick

AU - Loftus, Brendan

AU - Berg, Stefan

AU - Hewinson, R. Glyn

AU - Aranaz, Alicia

AU - Smith, Noel H.

PY - 2012/6/1

Y1 - 2012/6/1

N2 - Mycobacterium bovis isolates from the Iberian Peninsula are dominated by strains with spoligotype patterns deleted for spacer 21. Whole-genome sequencing of three Spanish strains with spacer 21 missing in their spoligotype pattern revealed a series of SNPs and subsequent screening of a selection of these SNPs identified one in gene guaA that is specific to these strains. This group of strains from the Iberian Peninsula missing spoligotype spacer 21 represents a new clonal complex of M. bovis, defined by the SNP profile with a distinct spoligotype signature. We have named this clonal complex European 2 (Eu2) and found that it was present at low frequency in both France and Italy and absent from the British Isles.

AB - Mycobacterium bovis isolates from the Iberian Peninsula are dominated by strains with spoligotype patterns deleted for spacer 21. Whole-genome sequencing of three Spanish strains with spacer 21 missing in their spoligotype pattern revealed a series of SNPs and subsequent screening of a selection of these SNPs identified one in gene guaA that is specific to these strains. This group of strains from the Iberian Peninsula missing spoligotype spacer 21 represents a new clonal complex of M. bovis, defined by the SNP profile with a distinct spoligotype signature. We have named this clonal complex European 2 (Eu2) and found that it was present at low frequency in both France and Italy and absent from the British Isles.

KW - Clonal complex

KW - Europe

KW - Mycobacterium bovis

KW - Phylogeny

KW - Whole genome sequencing

UR - http://www.scopus.com/inward/record.url?scp=84859918635&partnerID=8YFLogxK

U2 - 10.1016/j.meegid.2011.09.004

DO - 10.1016/j.meegid.2011.09.004

M3 - Article

C2 - 21945286

AN - SCOPUS:84859918635

SN - 1567-1348

VL - 12

SP - 866

EP - 872

JO - Infection, Genetics and Evolution

JF - Infection, Genetics and Evolution

IS - 4

ER -

European 2 - A clonal complex of Mycobacterium bovis dominant in the Iberian Peninsula

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