Exchanging murine and human immunoglobulin constant chains affects the kinetics and thermodynamics of antigen binding and chimeric antibody autoreactivity

Immunology and Microbiology

• Binding Antibody 100%
• Mouse 66%
• Chimeric Antibody 66%
• Monoclonal Antibodies 66%
• Glycosylation 66%
• Binding Affinity 33%
• Self Concept 33%
• Cryptococcus neoformans 33%
• Kinetics 33%
• Antigen 33%
• Human 33%
• Association Rate Constant 33%
• Conformational Transition 33%
• Thermodynamics 33%
• Human Immunoglobulin 33%
• Isotype 33%
• Allosterism 33%

Biochemistry, Genetics and Molecular Biology

• Glycosylation 66%
• Monoclonal Antibody 66%
• Antigen Binding 66%
• Mouse 66%
• Association Rate Constant 33%
• Thermodynamics 33%
• Allosteric Regulation 33%
• Kinetics 33%
• Human 33%
• Conformational Change 33%
• Self Concept 33%
• Cryptococcus neoformans 33%
• Peptide Mimetics 33%
• Binding Affinity 33%
• Surface Plasmon Resonance 33%