Familiarity- based stimulus generalization of conditioned suppression in rats is dependent on the perirhinal cortex.

Jasper Robinson, Emma J. Whitt, Rachel Rutter Horsley, Peter M. Jones

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

9 Dyfyniadau(SciVal)

Crynodeb

We report that bilateral. excitoxic lesions of the perirhinal cortex attenuate rats' familiarity-based stimulus generalization After surgery. rats were preexposed either to 2 auditory stimuli (A and B) or to only 1 auditory stimulus (B) Following preexposure, all rats received pairings of A and a footshock before assessment of generalized responding (conditioned suppression) to B Sham rats' generalization was greater when preexposure was to both A and 13 than when preexposure was to 13 only That pattern was abolished in lesioned rats, though no general deficiency was found in other measures of auditory processing Our findings suggest that the perirhinal cortex is required for rats to encode familiarity as part of stimulus representations
Iaith wreiddiolSaesneg
Tudalennau (o-i)587-599
Nifer y tudalennau12
CyfnodolynBehavioral Neuroscience
Cyfrol124
Rhif cyhoeddi5
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - Hyd 2010

Ôl bys

Gweld gwybodaeth am bynciau ymchwil 'Familiarity- based stimulus generalization of conditioned suppression in rats is dependent on the perirhinal cortex.'. Gyda’i gilydd, maen nhw’n ffurfio ôl bys unigryw.

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