Crynodeb
We identified a cluster of four two-component signal transduction genes that are necessary for proper progression of Myxococcus xanthus through development. redC to redF mutants developed and sporulated early, resulting in small, numerous, and disorganized fruiting bodies. Yeast two-hybrid analyses suggest that RedCDEF act in a single signaling pathway. The previously identified espA gene displays a phenotype similar to that of redCDEF. However, combined mutants defective in espA redCDEF exhibited a striking additive developmental phenotype, suggesting that EspA and RedC to RedF play independent roles in controlling developmental progression.
Iaith wreiddiol | Saesneg |
---|---|
Tudalennau (o-i) | 8191-8195 |
Nifer y tudalennau | 5 |
Cyfnodolyn | Journal of Bacteriology |
Cyfrol | 187 |
Rhif cyhoeddi | 23 |
Dynodwyr Gwrthrych Digidol (DOIs) | |
Statws | Cyhoeddwyd - Rhag 2005 |