TY - JOUR
T1 - Gene expression profiling to characterize sediment toxicity – a pilot study using Caenorhabditis elegans whole genome microarrays
AU - Menzel, Ralph
AU - Swain, Suresh C
AU - Hoess, Sebastian
AU - Claus, Evelyn
AU - Menzel, Stefanie
AU - Steinberg, Christian Ew
AU - Reifferscheid, Georg
AU - Stürzenbaum, Stephen R
N1 - Menzel, R., Swain, S. C., Hoess, S., Claus, E., Menzel, S., Steinberg, C. E., Reifferscheid, G., Stürzenbaum, S. R. (2009). Gene expression profiling to characterize sediment toxicity – a pilot study using Caenorhabditis elegans whole genome microarrays. BMC Genomics, Article No:10
PY - 2009
Y1 - 2009
N2 - Traditionally, toxicity of river sediments is assessed using whole sediment tests with benthic organisms. The challenge, however, is the differentiation between multiple effects caused by complex contaminant mixtures and the unspecific toxicity endpoints such as survival, growth or reproduction. The use of gene expression profiling facilitates the identification of transcriptional changes at the molecular level that are specific to the bio-available fraction of pollutants.
AB - Traditionally, toxicity of river sediments is assessed using whole sediment tests with benthic organisms. The challenge, however, is the differentiation between multiple effects caused by complex contaminant mixtures and the unspecific toxicity endpoints such as survival, growth or reproduction. The use of gene expression profiling facilitates the identification of transcriptional changes at the molecular level that are specific to the bio-available fraction of pollutants.
UR - http://hdl.handle.net/2160/9261
U2 - 10.1186/1471-2164-10-160
DO - 10.1186/1471-2164-10-160
M3 - Article
C2 - 19366437
SN - 1471-2164
VL - 10
JO - BMC Genomics
JF - BMC Genomics
M1 - 160
ER -