Genomic analysis of Mycobacterium tuberculosis complex strains used for production of purified protein derivative

Jacqueline Inwald; Jason Hinds; Si Palmer; James Dale; Philip D. Butcher; R. Glyn Hewinson; Stephen V. Gordon

doi:10.1128/JCM.41.8.3929-3932.2003

Genomic analysis of Mycobacterium tuberculosis complex strains used for production of purified protein derivative

Jacqueline Inwald, Jason Hinds, Si Palmer, James Dale, Philip D. Butcher, R. Glyn Hewinson, Stephen V. Gordon^*

^*Awdur cyfatebol y gwaith hwn

TB buchol, clefydau a rheolaeth

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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The genomes of the tuberculin production strains Mycobacterium bovis AN5 and Mycobacterium tuberculosis DT were compared to genome-sequenced tubercle bacilli by using DNA microarrays. Neither the AN5 nor DT strain suffered extensive gene deletions during in vitro passage. This suggests that bovine tuberculin made from M. bovis AN5 is suitable to detect infection with presently prevalent M. bovis strains.

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	3929-3932
Nifer y tudalennau	4
Cyfnodolyn	Journal of Clinical Microbiology
Cyfrol	41
Rhif cyhoeddi	8
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1128/JCM.41.8.3929-3932.2003
Statws	Cyhoeddwyd - 01 Awst 2003

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10.1128/JCM.41.8.3929-3932.2003

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Link to publication in Scopus

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title = "Genomic analysis of Mycobacterium tuberculosis complex strains used for production of purified protein derivative",

abstract = "The genomes of the tuberculin production strains Mycobacterium bovis AN5 and Mycobacterium tuberculosis DT were compared to genome-sequenced tubercle bacilli by using DNA microarrays. Neither the AN5 nor DT strain suffered extensive gene deletions during in vitro passage. This suggests that bovine tuberculin made from M. bovis AN5 is suitable to detect infection with presently prevalent M. bovis strains.",

author = "Jacqueline Inwald and Jason Hinds and Si Palmer and James Dale and Butcher, {Philip D.} and Hewinson, {R. Glyn} and Gordon, {Stephen V.}",

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T1 - Genomic analysis of Mycobacterium tuberculosis complex strains used for production of purified protein derivative

AU - Inwald, Jacqueline

AU - Hinds, Jason

AU - Palmer, Si

AU - Dale, James

AU - Butcher, Philip D.

AU - Hewinson, R. Glyn

AU - Gordon, Stephen V.

PY - 2003/8/1

Y1 - 2003/8/1

N2 - The genomes of the tuberculin production strains Mycobacterium bovis AN5 and Mycobacterium tuberculosis DT were compared to genome-sequenced tubercle bacilli by using DNA microarrays. Neither the AN5 nor DT strain suffered extensive gene deletions during in vitro passage. This suggests that bovine tuberculin made from M. bovis AN5 is suitable to detect infection with presently prevalent M. bovis strains.

AB - The genomes of the tuberculin production strains Mycobacterium bovis AN5 and Mycobacterium tuberculosis DT were compared to genome-sequenced tubercle bacilli by using DNA microarrays. Neither the AN5 nor DT strain suffered extensive gene deletions during in vitro passage. This suggests that bovine tuberculin made from M. bovis AN5 is suitable to detect infection with presently prevalent M. bovis strains.

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U2 - 10.1128/JCM.41.8.3929-3932.2003

DO - 10.1128/JCM.41.8.3929-3932.2003

M3 - Article

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IS - 8

ER -

Genomic analysis of Mycobacterium tuberculosis complex strains used for production of purified protein derivative

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NDC y CU

Mynediad at Ddogfen

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Ffeiliau eraill a chysylltiadau

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