Initiation of programmed cell death in self-incompatibility: role for cytoskeleton modifications and several caspase-like activities

Maurice Bosch, Natalie S. Poulter, Sabina Vatovec, Vernonica E. Franklin-Tong

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

31 Dyfyniadau(SciVal)
164 Wedi eu Llwytho i Lawr (Pure)

Crynodeb

Programmed cell death (PCD) is an important and universal process regulating precise death of unwanted cells in eukaryotes. In plants, the existence of PCD has been firmly established for about a decade, and many components shown to be involved in apoptosis/PCD in mammalian systems are found in plant cells undergoing PCD. Here, we review work from our lab demonstrating the involvement of PCD in the self-incompatibility response in Papaver rhoeas pollen. This utilization of PCD as a consequence of a specific pollen–pistil interaction provides a very neat way to destroy unwanted ‘self’, but not ‘non-self’ pollen. We discuss recent data providing evidence for SI-induced activation of several caspase-like activities and suggest that an acidification of the cytosol may be a key turning point in the activation of caspase-like proteases executing PCD. We also review data showing the involvement of the actin and microtubule cytoskeletons as well as that of a MAPK in signalling to caspase-mediated PCD. Potential links between these various components in signalling to PCD are discussed. Together, this begins to build a picture of PCD in a single cell system, triggered by a receptor–ligand interaction.
Iaith wreiddiolSaesneg
Tudalennau (o-i)879-887
Nifer y tudalennau9
CyfnodolynMolecular Plant
Cyfrol1
Rhif cyhoeddi6
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 17 Hyd 2008

Ôl bys

Gweld gwybodaeth am bynciau ymchwil 'Initiation of programmed cell death in self-incompatibility: role for cytoskeleton modifications and several caspase-like activities'. Gyda’i gilydd, maen nhw’n ffurfio ôl bys unigryw.

Dyfynnu hyn