Sensory mediation of memory blocking stressors in the pond snail Lymnaea stagnalis

Sarah Dalesman*, Vikram Karnik, Ken Lukowiak

*Awdur cyfatebol y gwaith hwn

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid


The great pond snail, Lymnaea stagnalis, is commonly used as a model species to study how stress affects the ability to form long-term memory (LTM); however, we still have little information about how the snail senses stressful stimuli. The osphradium is an external sensory organ that demonstrates electrophysiological responses to a variety of external chemical stimuli. We examined the role, if any, played by the osphradium in sensing two environmental stressors, crowding and low environmental calcium, both known to block LTM in intact animals. We severed the osphradial nerve, blocking external sensory input from this organ to the central nervous system, and then exposed the snails to low environmental calcium or crowding stress to assess whether these stressors continued to block LTM formation. When exposed to low environmental calcium, snails with their osphradial nerve severed responded as if they were maintained in our standard calcium environment. That is, they did not respond to low calcium as a stressor blocking LTM; therefore, the osphradium plays a crucial role in mediating how snails respond to this stressor. However, following crowding, LTM formation was blocked in both control groups and snails that had the osphradial nerve severed, indicating that sensory information from the osphradium is not required to sense crowded conditions. Together these data show that two stressors that result in the same behavioural phenotype, blocking LTM formation, do so via two distinct sensory pathways.

Iaith wreiddiolSaesneg
Tudalennau (o-i)2528-2533
Nifer y tudalennau6
CyfnodolynJournal of Experimental Biology
Rhif cyhoeddi15
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 01 Awst 2011

Ôl bys

Gweld gwybodaeth am bynciau ymchwil 'Sensory mediation of memory blocking stressors in the pond snail Lymnaea stagnalis'. Gyda’i gilydd, maen nhw’n ffurfio ôl bys unigryw.

Dyfynnu hyn