State-of the art methodologies dictate new standards for phylogenetic analysis

Maria Anisimova*, David A. Liberles, Herve Philippe, Jim Provan, Tal Pupko, Arndt von Haeseler

*Awdur cyfatebol y gwaith hwn

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygl olygyddoladolygiad gan gymheiriaid

48 Dyfyniadau (Scopus)
145 Wedi eu Llwytho i Lawr (Pure)

Crynodeb

The intention of this editorial is to steer researchers through methodological choices in molecular evolution, drawing on the combined expertise of the authors. Our aim is not to review the most advanced methods for a specific task. Rather, we define several general guidelines to help with methodology choices at different stages of a typical phylogenetic 'pipeline'. We are not able to provide exhaustive citation of a literature that is vast and plentiful, but we point the reader to a set of classical textbooks that reflect the state-of-the-art. We do not wish to appear overly critical of outdated methodology but rather provide some practical guidance on the sort of issues which should be considered. We stress that a reported study should be well-motivated and evaluate a specific hypothesis or scientific question. However, a publishable study should not be merely a compilation of available sequences for a protein family of interest followed by some standard analyses, unless it specifically addresses a scientific hypothesis or question. The rapid pace at which sequence data accumulate quickly outdates such publications. Although clearly, discoveries stemming from data mining, reports of new tools and databases and review papers are also desirable.

Iaith wreiddiolSaesneg
Rhif yr erthygl161
Nifer y tudalennau8
CyfnodolynBMC Evolutionary Biology
Cyfrol13
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 01 Awst 2013

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