Synthesis of Fully Substituted Polyhydroxylated Pyrrolizidines via Cope-House Cyclization

Wei Zhang, Kasumi Sato, Atsushi Kato, Yue-mei Jia, Xiang-guo Hu, Francis X. Wilson, Renate Van Well, Graeme Horne, George W. J. Fleet, Robert J. Nash, Chu-yi Yu

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

48 Dyfyniadau (Scopus)

Crynodeb

Total synthesis of the proposed structure of (-)-hyacinthacine C(5) and its epimers at C6 and C7 is described. A key step of the synthesis was the construction of the bicyclic pyrrolizidine system by means of a nucleophilic addition of a dithiane to a cyclic nitrone followed by a Cope House cyclization.
Iaith wreiddiolSaesneg
Tudalennau (o-i)4414-4417
Nifer y tudalennau4
CyfnodolynOrganic Letters
Cyfrol13
Rhif cyhoeddi16
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 19 Awst 2011

Ôl bys

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