T cell receptor signalling inspired kernel density estimation and anomaly detection

Nick D. L. Owens, Andy Greensted, Jon Timmis, Andy Tyrrell

Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion CynhadleddTrafodion Cynhadledd (Nid-Cyfnodolyn fathau)

20 Dyfyniadau(SciVal)

Crynodeb

The T cell is able to perform fine-grained anomaly detection via its T Cell Receptor and intracellular signalling networks. We abstract from models of T Cell signalling to develop a new Artificial Immune System concepts involving the internal components of the TCR. We show that the concepts of receptor signalling have a natural interpretation as Parzen Window Kernel Density Estimation applied to anomaly detection. We then demonstrate how the dynamic nature of the receptors allows anomaly detection when probability distributions vary in time.

Iaith wreiddiolSaesneg
TeitlArtificial Immune Systems - 8th International Conference, ICARIS 2009, Proceedings
GolygyddionPaul S. Andrews, Jon Timmis, Nick D. L. Owens, Andy M. Tyrrell, Uwe Aickelin, Emma Hart, Andrew Hone
CyhoeddwrSpringer Nature
Tudalennau122-135
Nifer y tudalennau14
ISBN (Argraffiad)3642032451, 9783642032455
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 2009
Digwyddiad8th International Conference on Artificial Immune Systems, ICARIS 2009 - York, Teyrnas Unedig Prydain Fawr a Gogledd Iwerddon
Hyd: 09 Awst 200912 Awst 2009

Cyfres gyhoeddiadau

EnwLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Cyfrol5666 LNCS
ISSN (Argraffiad)0302-9743
ISSN (Electronig)1611-3349

Cynhadledd

Cynhadledd8th International Conference on Artificial Immune Systems, ICARIS 2009
Gwlad/TiriogaethTeyrnas Unedig Prydain Fawr a Gogledd Iwerddon
DinasYork
Cyfnod09 Awst 200912 Awst 2009

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