Temperature-dependent expression of the chromosomal β-lactamase gene in a strain of Pseudomonas aeruginosa

R. G. Hewinson; W. W. Nichols

doi:10.1099/00222615-24-3-263

Temperature-dependent expression of the chromosomal β-lactamase gene in a strain of Pseudomonas aeruginosa

R. G. Hewinson, W. W. Nichols

TB buchol, clefydau a rheolaeth

University of Oxford

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

5 Dyfyniadau (Scopus)

Crynodeb

A strain of Pseudomonas aeruginosa (3-Post) was resistant to cefsulodin and ceftazidime at 37°C but sensitive at 20°C. Resistance was mediated by chromosomally-encoded β lactamase which was synthesised at a high level during growth above 30°C but at a low, inducible level during growth below 27°C.

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	263-265
Nifer y tudalennau	3
Cyfnodolyn	Journal of Medical Microbiology
Cyfrol	24
Rhif cyhoeddi	3
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1099/00222615-24-3-263
Statws	Cyhoeddwyd - 01 Tach 1987

Mynediad at Ddogfen

10.1099/00222615-24-3-263

Cysylltiad parhaol

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Link to publication in Scopus

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@article{861fb96bc8f6468b9a216aaf9ba669c8,

title = "Temperature-dependent expression of the chromosomal β-lactamase gene in a strain of Pseudomonas aeruginosa",

abstract = "A strain of Pseudomonas aeruginosa (3-Post) was resistant to cefsulodin and ceftazidime at 37°C but sensitive at 20°C. Resistance was mediated by chromosomally-encoded β lactamase which was synthesised at a high level during growth above 30°C but at a low, inducible level during growth below 27°C.",

keywords = "Cefsulodin/pharmacology, Ceftazidime/pharmacology, Cephalosporins/metabolism, Chromosomes, Bacterial/physiology, Drug Resistance, Microbial, Gene Expression Regulation, Pseudomonas aeruginosa/drug effects, Temperature, beta-Lactamases/genetics",

author = "Hewinson, {R. G.} and Nichols, {W. W.}",

year = "1987",

month = nov,

day = "1",

doi = "10.1099/00222615-24-3-263",

language = "English",

volume = "24",

pages = "263--265",

journal = "Journal of Medical Microbiology",

issn = "0022-2615",

publisher = "Microbiology Society",

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TY - JOUR

T1 - Temperature-dependent expression of the chromosomal β-lactamase gene in a strain of Pseudomonas aeruginosa

AU - Hewinson, R. G.

AU - Nichols, W. W.

PY - 1987/11/1

Y1 - 1987/11/1

N2 - A strain of Pseudomonas aeruginosa (3-Post) was resistant to cefsulodin and ceftazidime at 37°C but sensitive at 20°C. Resistance was mediated by chromosomally-encoded β lactamase which was synthesised at a high level during growth above 30°C but at a low, inducible level during growth below 27°C.

AB - A strain of Pseudomonas aeruginosa (3-Post) was resistant to cefsulodin and ceftazidime at 37°C but sensitive at 20°C. Resistance was mediated by chromosomally-encoded β lactamase which was synthesised at a high level during growth above 30°C but at a low, inducible level during growth below 27°C.

KW - Cefsulodin/pharmacology

KW - Ceftazidime/pharmacology

KW - Cephalosporins/metabolism

KW - Chromosomes, Bacterial/physiology

KW - Drug Resistance, Microbial

KW - Gene Expression Regulation

KW - Pseudomonas aeruginosa/drug effects

KW - Temperature

KW - beta-Lactamases/genetics

UR - http://www.scopus.com/inward/record.url?scp=0023199550&partnerID=8YFLogxK

U2 - 10.1099/00222615-24-3-263

DO - 10.1099/00222615-24-3-263

M3 - Article

C2 - 3118037

AN - SCOPUS:0023199550

SN - 0022-2615

VL - 24

SP - 263

EP - 265

JO - Journal of Medical Microbiology

JF - Journal of Medical Microbiology

IS - 3

ER -

Temperature-dependent expression of the chromosomal β-lactamase gene in a strain of Pseudomonas aeruginosa

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Mynediad at Ddogfen

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