The effect of administration of fenbendazole on the microbial hindgut population of the horse

Laura Crotch-Harvey, Leigh-Anne Thomas, Hilary Worgan, Jamie-Leigh Douglas, Diane E. Gilby, Neil McEwan

Allbwn ymchwil: Cyfraniad at gyfnodolynSylwadau/Trafodaethau adolygiad gan gymheiriaid

8 Dyfyniadau(SciVal)
135 Wedi eu Llwytho i Lawr (Pure)

Crynodeb

Anthelmintics are used as anti-worming agents. Although known to affect their target organisms, nothing has been published regarding their effect on other digestive tract organisms or on metabolites produced by them. The current work investigated effects of fenbendazole, a benzimidazole anthelmintic, on bacteria and ciliates in the equine digestive tract and on and their major metabolites. Animals receiving anthelmintic treatment had high faecal egg counts relative to controls. Analysis was performed over two weeks, with temporal differences detected in bacterial populations but with no other significant differences detected. This suggests fenbendazole has no detectable effect on organisms other than its targets. Moreover it does not appear to make a contribution to changing the resulting metabolome
Iaith wreiddiolSaesneg
Tudalennau (o-i)47-51
Nifer y tudalennau5
CyfnodolynJournal of Equine Science
Cyfrol29
Rhif cyhoeddi2
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 06 Gorff 2018

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Gweld gwybodaeth am bynciau ymchwil 'The effect of administration of fenbendazole on the microbial hindgut population of the horse'. Gyda’i gilydd, maen nhw’n ffurfio ôl bys unigryw.

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