The effect of mycophenolic acid on the cell cycle of Candida albicans

Carmel M. Quinn; Virginia C. Bugeja; Joseph A. Gallagher; Peter A. Whittaker

doi:10.1007/BF02282799

The effect of mycophenolic acid on the cell cycle of Candida albicans

Carmel M. Quinn, Virginia C. Bugeja, Joseph A. Gallagher, Peter A. Whittaker

Gwyddorau Bywyd

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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Mycophenolic acid inhibited the growth ofCandida albicans. Cultures exposed to a concentration of 8.4 μg ml−1 mycophenolic acid were found to exhibit cell cycle arrest with two or more buds. Nuclear staining revealed that these were nucleate implying a possible defect in cytokinesis.

The results are discussed in relation to the possible mode of action of mycophenolic acid.

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	165-168
Nifer y tudalennau	4
Cyfnodolyn	Mycopathologia
Cyfrol	111
Rhif cyhoeddi	3
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1007/BF02282799
Statws	Cyhoeddwyd - Medi 1990

Mynediad at Ddogfen

10.1007/BF02282799

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Dolen barhaus

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title = "The effect of mycophenolic acid on the cell cycle of Candida albicans",

abstract = "Mycophenolic acid inhibited the growth ofCandida albicans. Cultures exposed to a concentration of 8.4 μg ml−1 mycophenolic acid were found to exhibit cell cycle arrest with two or more buds. Nuclear staining revealed that these were nucleate implying a possible defect in cytokinesis.The results are discussed in relation to the possible mode of action of mycophenolic acid.",

keywords = "Candida albicans, mycophenolic acid, cell cycle",

author = "Quinn, {Carmel M.} and Bugeja, {Virginia C.} and Gallagher, {Joseph A.} and Whittaker, {Peter A.}",

year = "1990",

month = sep,

doi = "10.1007/BF02282799",

language = "English",

volume = "111",

pages = "165--168",

journal = "Mycopathologia",

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T1 - The effect of mycophenolic acid on the cell cycle of Candida albicans

AU - Quinn, Carmel M.

AU - Bugeja, Virginia C.

AU - Gallagher, Joseph A.

AU - Whittaker, Peter A.

PY - 1990/9

Y1 - 1990/9

N2 - Mycophenolic acid inhibited the growth ofCandida albicans. Cultures exposed to a concentration of 8.4 μg ml−1 mycophenolic acid were found to exhibit cell cycle arrest with two or more buds. Nuclear staining revealed that these were nucleate implying a possible defect in cytokinesis.The results are discussed in relation to the possible mode of action of mycophenolic acid.

AB - Mycophenolic acid inhibited the growth ofCandida albicans. Cultures exposed to a concentration of 8.4 μg ml−1 mycophenolic acid were found to exhibit cell cycle arrest with two or more buds. Nuclear staining revealed that these were nucleate implying a possible defect in cytokinesis.The results are discussed in relation to the possible mode of action of mycophenolic acid.

KW - Candida albicans

KW - mycophenolic acid

KW - cell cycle

UR - http://www.scopus.com/inward/record.url?scp=0025162526&partnerID=8YFLogxK

U2 - 10.1007/BF02282799

DO - 10.1007/BF02282799

M3 - Article

SN - 0301-486X

VL - 111

SP - 165

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JO - Mycopathologia

JF - Mycopathologia

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ER -

The effect of mycophenolic acid on the cell cycle of Candida albicans

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Mynediad at Ddogfen

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