The pathways of complement

Jonathan M. Aitken, Tim Clarke, Jonathan I. Timmis

Allbwn ymchwil: Pennod mewn Llyfr/Adroddiad/Trafodion CynhadleddTrafodion Cynhadledd (Nid-Cyfnodolyn fathau)

1 Dyfyniad (Scopus)

Crynodeb

The natural world has developed very effective methods for dealing with pathogens that are invading an organism. By taking inspiration from the in-built, innate, response this paper develops a new algorithm that mimics activation path of the Alternative Pathway of Complement. The Alternative Pathway is triggered by cell surfaces. If the surfaces display safe characteristics then a strong suppression process prevents activation. In the case of non-safe surfaces a positive feedback loop rapidly identifies the location marking it for removal by phagocytosis.

Iaith wreiddiolSaesneg
TeitlArtificial Immune Systems - 7th International Conference, ICARIS 2008, Proceedings
CyhoeddwrSpringer Nature
Tudalennau364-375
Nifer y tudalennau12
ISBN (Argraffiad)3540850716, 9783540850717
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - 2008
Digwyddiad7th International Conference on Artificial Immune Systems, ICARIS 2008 - Phuket, Gwlad Thai
Hyd: 10 Awst 200813 Awst 2008

Cyfres gyhoeddiadau

EnwLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Cyfrol5132 LNCS
ISSN (Argraffiad)0302-9743
ISSN (Electronig)1611-3349

Cynhadledd

Cynhadledd7th International Conference on Artificial Immune Systems, ICARIS 2008
Gwlad/TiriogaethGwlad Thai
DinasPhuket
Cyfnod10 Awst 200813 Awst 2008

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