The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses

Colin M Fitzsimmons; Frances M Jones; Alex Stearn; Iain W Chalmers; Karl F Hoffmann; Jakub Wawrzyniak; Shona Wilson; Narcis B Kabatereine; David W Dunne

doi:10.1371/journal.pntd.0001593

The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses

Colin M Fitzsimmons, Frances M Jones, Alex Stearn, Iain W Chalmers, Karl F Hoffmann, Jakub Wawrzyniak, Shona Wilson, Narcis B Kabatereine, David W Dunne

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Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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A human IgE response to Sm22.6 (a dominant IgE target in Schistosoma mansoni) is associated with the development of partial immunity. Located inside the tegument, the molecule belongs to a family of proteins from parasitic platyhelminths, the Tegument-Allergen-Like proteins (TALs). In addition to containing dynein-light-chain domains, these TALs also contain EF-hand domains similar to those found in numerous EF-hand allergens.

Iaith wreiddiol	Saesneg
Rhif yr erthygl	e1593
Cyfnodolyn	PLoS Neglected Tropical Diseases
Cyfrol	6
Rhif cyhoeddi	4
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1371/journal.pntd.0001593
Statws	Cyhoeddwyd - 03 Ebr 2012

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10.1371/journal.pntd.0001593

Genome-Wide Prediction of Functional Gene-Gene Interactions Inferred from Patterns of Genetic Differentiation in Mice and MenFersiwn derfynol wedi’i chyhoeddi, 247 KB

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http://hdl.handle.net/2160/12421

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Fitzsimmons, C. M., Jones, F. M., Stearn, A., Chalmers, I. W., Hoffmann, K. F., Wawrzyniak, J., Wilson, S., Kabatereine, N. B., & Dunne, D. W. (2012). The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses. PLoS Neglected Tropical Diseases, 6(4), erthygl e1593. https://doi.org/10.1371/journal.pntd.0001593

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title = "The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses",

abstract = "A human IgE response to Sm22.6 (a dominant IgE target in Schistosoma mansoni) is associated with the development of partial immunity. Located inside the tegument, the molecule belongs to a family of proteins from parasitic platyhelminths, the Tegument-Allergen-Like proteins (TALs). In addition to containing dynein-light-chain domains, these TALs also contain EF-hand domains similar to those found in numerous EF-hand allergens.",

author = "Fitzsimmons, {Colin M} and Jones, {Frances M} and Alex Stearn and Chalmers, {Iain W} and Hoffmann, {Karl F} and Jakub Wawrzyniak and Shona Wilson and Kabatereine, {Narcis B} and Dunne, {David W}",

note = "Fitzsimmons CM, Jones FM, Stearn A, Chalmers IW, Hoffmann KF, et al. (2012) The Schistosoma mansoni Tegumental-Allergen-Like (TAL) Protein Family: Influence of Developmental Expression on Human IgE Responses. PLoS Negl Trop Dis 6 (4): e1593",

year = "2012",

month = apr,

day = "3",

doi = "10.1371/journal.pntd.0001593",

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T1 - The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses

AU - Fitzsimmons, Colin M

AU - Jones, Frances M

AU - Stearn, Alex

AU - Chalmers, Iain W

AU - Hoffmann, Karl F

AU - Wawrzyniak, Jakub

AU - Wilson, Shona

AU - Kabatereine, Narcis B

AU - Dunne, David W

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N2 - A human IgE response to Sm22.6 (a dominant IgE target in Schistosoma mansoni) is associated with the development of partial immunity. Located inside the tegument, the molecule belongs to a family of proteins from parasitic platyhelminths, the Tegument-Allergen-Like proteins (TALs). In addition to containing dynein-light-chain domains, these TALs also contain EF-hand domains similar to those found in numerous EF-hand allergens.

AB - A human IgE response to Sm22.6 (a dominant IgE target in Schistosoma mansoni) is associated with the development of partial immunity. Located inside the tegument, the molecule belongs to a family of proteins from parasitic platyhelminths, the Tegument-Allergen-Like proteins (TALs). In addition to containing dynein-light-chain domains, these TALs also contain EF-hand domains similar to those found in numerous EF-hand allergens.

UR - http://hdl.handle.net/2160/12421

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DO - 10.1371/journal.pntd.0001593

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JO - PLoS Neglected Tropical Diseases

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The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses

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Mynediad at Ddogfen

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