Validation of the BrockTB Stat-Pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy

Mark A. Chambers; Tim Crawshaw; Sue Waterhouse; Richard Delahay; R. Glyn Hewinson; Konstantin P. Lyashchenko

doi:10.1128/JCM.02117-07

Validation of the BrockTB Stat-Pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy

Mark A. Chambers, Tim Crawshaw, Sue Waterhouse, Richard Delahay, R. Glyn Hewinson, Konstantin P. Lyashchenko

TB buchol, clefydau a rheolaeth

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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A lateral-flow immunoassay (BrockTB Stat-Pak) for detecting tuberculosis in Eurasian badgers was 49% sensitive and 93% specific against culture for M. bovis (n = 1,464) at necropsy. However, the sensitivity was significantly higher (66 to 78%) in animals with more severe tuberculosis, indicating that the BrockTB Stat-Pak may be useful for the detection of badgers with the greatest risk of transmitting disease.

Iaith wreiddiol	Saesneg
Tudalennau (o-i)	1498-1500
Nifer y tudalennau	3
Cyfnodolyn	Journal of Clinical Microbiology
Cyfrol	46
Rhif cyhoeddi	4
Dyddiad ar-lein cynnar	13 Chwef 2008
Dynodwyr Gwrthrych Digidol (DOIs)	https://doi.org/10.1128/JCM.02117-07
Statws	Cyhoeddwyd - 01 Ebr 2008

NDC y CU

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10.1128/JCM.02117-07

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Link to publication in Scopus

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title = "Validation of the BrockTB Stat-Pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy",

abstract = "A lateral-flow immunoassay (BrockTB Stat-Pak) for detecting tuberculosis in Eurasian badgers was 49% sensitive and 93% specific against culture for M. bovis (n = 1,464) at necropsy. However, the sensitivity was significantly higher (66 to 78%) in animals with more severe tuberculosis, indicating that the BrockTB Stat-Pak may be useful for the detection of badgers with the greatest risk of transmitting disease.",

author = "Chambers, {Mark A.} and Tim Crawshaw and Sue Waterhouse and Richard Delahay and Hewinson, {R. Glyn} and Lyashchenko, {Konstantin P.}",

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Validation of the BrockTB Stat-Pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy. / Chambers, Mark A.; Crawshaw, Tim; Waterhouse, Sue et al.
Yn: Journal of Clinical Microbiology, Cyfrol 46, Rhif 4, 01.04.2008, t. 1498-1500.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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T1 - Validation of the BrockTB Stat-Pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy

AU - Chambers, Mark A.

AU - Crawshaw, Tim

AU - Waterhouse, Sue

AU - Delahay, Richard

AU - Hewinson, R. Glyn

AU - Lyashchenko, Konstantin P.

PY - 2008/4/1

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N2 - A lateral-flow immunoassay (BrockTB Stat-Pak) for detecting tuberculosis in Eurasian badgers was 49% sensitive and 93% specific against culture for M. bovis (n = 1,464) at necropsy. However, the sensitivity was significantly higher (66 to 78%) in animals with more severe tuberculosis, indicating that the BrockTB Stat-Pak may be useful for the detection of badgers with the greatest risk of transmitting disease.

AB - A lateral-flow immunoassay (BrockTB Stat-Pak) for detecting tuberculosis in Eurasian badgers was 49% sensitive and 93% specific against culture for M. bovis (n = 1,464) at necropsy. However, the sensitivity was significantly higher (66 to 78%) in animals with more severe tuberculosis, indicating that the BrockTB Stat-Pak may be useful for the detection of badgers with the greatest risk of transmitting disease.

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U2 - 10.1128/JCM.02117-07

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ER -

Validation of the BrockTB Stat-Pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy

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