Research output per year
Research output per year
Personal profile
Profile
Amanda is a member of the Ser Cymru team within the Centre for Excellence in Bovine Tuberculosis based in Carwyn James Building.
Her current research activities surround the understanding of host-pathogen interaction at the very early stages of infection leading to disease progression – specifically to investigate the interaction of M. bovis with the innate immune system of the bovine host. Amanda's research activities are supported by a strong background in immunology and most recently comprehensive training in mycobacteriology.
Centre for Excellence in Bovine Tuberculosis research program is underpinned by 3 main themes:
- Fundamental understanding of early innate immune events leading to infectious disease
- Understanding the role of Mycobacterial genetic strain diversity on immune interaction and disease progression
- Development of novel paired diagnostics and vaccine technologies
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- QR180 Immunology
- Innate Immunology
- Antigen Presenting Cells
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Characterisation of the bovine C-type lectin receptor Mincle and potential evidence for an endogenous ligand
Holder, A., Kolakowski, J., Rosentreter, C., Knuepfer, E., Jégouzo, S. A. F., Rosenwasser, O., Harris, H., Baumgaertel, L., Gibson, A. & Werling, D., 19 May 2023, In: Frontiers in Immunology. 14, 14 p., 1189587.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)91 Downloads (Pure) -
Detecting mecA in Faecal Samples: A Tool for Assessing Carriage of Meticillin-Resistant Staphylococci in Pets and Owners in the Microbiological ‘Fast Age’?
Frosini, S.-M., Gallow, G., Gibson, A., Menezes, J., Pomba, C. & Loeffler, A., 13 Jan 2023, In: Microbiology Research. 14, 1, p. 60-66 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile54 Downloads (Pure) -
Defining the Genes Required for Survival of Mycobacterium bovis in the Bovine Host Offers Novel Insights into the Genetic Basis of Survival of Pathogenic Mycobacteria
Gibson, A., Stiens, J., Passmore, I., Faulkner, V., Miculob, J., Willcocks, S., Coad, M., Berg, S., Werling, D., Wren, B., Nobeli, I., Villarreal-Ramos, B. & Kendall, S. L., 30 Aug 2022, In: mBIO. 13, 4, 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)110 Downloads (Pure) -
In Vitro Supplementation of Copper Modulates the Functional Th1/Th2 Phenotype of Peripheral Blood Mononuclear Cells in Cattle
Bunting, M., Challice, B., Gibson, A. & van Winden, S., 19 Sept 2021, In: Animals. 11, 9, p. e2739 2739.Research output: Contribution to journal › Article › peer-review
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Probing Differences in Gene Essentiality Between the Human and Animal Adapted Lineages of the Mycobacterium tuberculosis Complex Using TnSeq
Gibson, A. J., Passmore, I. J., Faulkner, V., Xia, D., Nobeli, I., Stiens, J., Willcocks, S., Clark, T. G., Sobkowiak, B., Werling, D., Villarreal-Ramos, B., Wren, B. W. & Kendall, S. L., 24 Dec 2021, In: Frontiers in Veterinary Science. 8, 760717.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits
Faulkner, V., Cox, A. A., Goh, S., van Bohemen, A., Gibson, A. J., Liebster, O., Wren, B. W., Willcocks, S. & Kendall, S. L., 01 Feb 2021, In: Frontiers in Microbiology. 11, 10 p., 619427.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)96 Downloads (Pure) -
Single Nucleotide Polymorphisms in the Bovine TLR2 Extracellular Domain Contribute to Breed and Species-Specific Innate Immune Functionality
Bartens, M. C., Gibson, A. J., Etherington, G. J., Di Palma, F., Holder, A., Werling, D. & Willcocks, S., 23 Dec 2021, In: Frontiers in Immunology. 12, 764390.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
The Role of TLR2 and TLR4 in Recognition and Uptake of the Apicomplexan Parasite Eimeria bovis and Their Effects on NET Formation
Muñoz-Caro, T., Gibson, A. J., Conejeros, I., Werling, D., Taubert, A. & Hermosilla, C., 24 Jan 2021, In: Pathogens. 10, 2, 15 p., 118.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)98 Downloads (Pure) -
Enterobactin Deficiency in a Coliform Mastitis Isolate Decreases Its Fitness in a Murine Model: A Preliminary Host–Pathogen Interaction Study
Vander Elst, N., Breyne, K., Steenbrugge, J., Gibson, A. J., Smith, D. G. E., Germon, P., Werling, D. & Meyer, E., 09 Nov 2020, In: Frontiers in Veterinary Science. 7, 11 p., 576583.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)141 Downloads (Pure) -
Antimicrobial polymers: The potential replacement of existing antibiotics?
Kamaruzzaman, N. F., Tan, L. P., Hamdan, R. H., Choong, S. S., Wong, W. K., Gibson, A. J., Chivu, A. & De Fatima Pina, M., 04 Jun 2019, In: International Journal of Molecular Sciences. 20, 11, 31 p., 2747.Research output: Contribution to journal › Review Article › peer-review
Open AccessFile189 Citations (Scopus)123 Downloads (Pure) -
Short communication: Pegbovigrastim treatment in vivo does not affect granulocyte ability to migrate to endometrial cells and kill bacteria in vitro in healthy cows
Tombácz, K., Peters, L. M., Chang, Y. M., Steele, M., Werling, D. & Gibson, A. J., 01 Oct 2019, In: Journal of Dairy Science. 102, 10, p. 9389-9395 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)99 Downloads (Pure)
Projects
- 1 Finished
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Persistence of Mycobacterium bovis: Understanding the impact of persistent phenotypes on function - Beth Wilkinson
Gibson, A. (PI)
Society for Applied Michobiology (SfAM)
01 Jul 2022 → 31 Aug 2022
Project: Externally funded research