Charalampos' research interests focus on the diplomacy of middle powers in international politics. His research examines the strategies of middle powers in international institutions, such as the World Trade Organisation and the United Nations Security Council. He specialises in the foreign policy of states such as Brazil, India and South Africa, and in particular the capacity of these states to act as leaders of the global South and operate as bridge-builders in multilateral negotiations. His research also focuses on the relevance of Global IR theories for understanding the agency of middle powers in the global order.

Charalampos joined the Department of International Politics in September 2012. He was awarded his PhD at the University of Warwick in 2012 and his thesis examined the diplomacy of India and South Africa in the World Trade Organisation. He is Editor-in-Chief for the International Relations journal.