Research output per year
Research output per year
Personal profile
Research interests
My research focuses on the myxobacterial predator Myxococcus xanthus and how it preys upon other microbes. We are studying natural myxobacterial isolates using a variety of genomic, proteomic and phenotypic techniques to identify the genes conferring antimicrobial activity. Particular topics of interest include the predatory vesicles shed by myxobacteria, and myxobacterial signalling pathways and how they alter behaviour in response to a changing environment.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Profiles
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Lewis Fisher
Person: Doctor of Philosophy
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Emily Radford
Person: Doctor of Philosophy
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A Synthetic Polymicrobial Community Biofilm Model Demonstrates Spatial Partitioning, Tolerance to Antimicrobial Treatment, Reduced Metabolism, and Small Colony Variants Typical of Chronic Wound Biofilms
Khalid, A., Cookson, A. R., Whitworth, D. E., Beeton, M. L., Robins, L. I. & Maddocks, S. E., 10 Jan 2023, In: Pathogens. 12, 1, 15 p., 118.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Downloads (Pure) -
In Silico and In Vitro Analyses Reveal Promising Antimicrobial Peptides from Myxobacteria
Arakal, B. S., Whitworth, D. E., James, P. E., Rowlands, R., Madhusoodanan, N. P. T., Baijoo, M. R. & Livingstone, P. G., 01 Feb 2023, In: Probiotics and Antimicrobial Proteins. 15, 1, p. 202-214 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Myxobacterial Predation: A Standardised Lawn Predation Assay Highlights Strains with Unusually Efficient Predatory Activity
Zwarycz, A. S. & Whitworth, D. E., 04 Feb 2023, In: Microorganisms. 11, 2, 19 p., 398.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure) -
Predatory Strategies of Myxococcus xanthus: Prey Susceptibility to OMVs and Moonlighting Enzymes
Zwarycz, A. S., Page, T., Nikolova, G., Radford, E. J. & Whitworth, D. E., 29 Mar 2023, In: Microorganisms. 11, 4, 16 p., 874.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
Increasing creative self-efficacy: Developing the confidence of biochemistry undergraduates to innovate
Payne, S. & Whitworth, D., 16 May 2022, In: Biochemistry and Molecular Biology Education. 50, 3, p. 296-306 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Downloads (Pure) -
Myxobacteria: Physiology and Regulation
Whitworth, D., 12 Apr 2022, In: Microorganisms. 10, 4, 2 p., 805.Research output: Contribution to journal › Editorial
Open AccessFile14 Downloads (Pure) -
Corrigendum to: “Comparative genomics and pan-genomics of the Myxococcaceae, including a description of five novel species: Myxococcus eversor sp. nov., Myxococcus llanfairpwllgwyngyllgogerychwyrndrobwllllantysiliogogogochensis sp. nov., Myxococcus vastator sp. nov., Pyxidicoccus caerfyrddinensis sp. nov. and Pyxidicoccus trucidator sp. nov.” [Genome Biol. Evol. 12(12) (2020) 2289-2302]
Chambers, J., Sparks, N., Sydney, N., Livingstone, P. G., Cookson, A. R. & Whitworth, D. E., 30 Apr 2021, In: Genome Biology and Evolution. 13, 4, 2 p., evab040.Research output: Contribution to journal › Correction › peer-review
Open AccessFile41 Downloads (Pure) -
Evolutionary history expands the range of signaling interactions in hybrid multikinase networks
Ortet, P., Fochesato, S., Bitbol, A-F., Whitworth, D. E., Lalaouna, D., Santaella, C., Heulin, T., Achouak, W. & Barakat, M., 01 Dec 2021, In: Scientific Reports. 11, 1, p. 11763 12 p., 11763.Research output: Contribution to journal › Article › peer-review
Open AccessFile75 Downloads (Pure) -
The Genetics of Prey Susceptibility to Myxobacterial Predation: A Review, including an Investigation into Pseudomonas aeruginosa Mutations Affecting Predation by Myxococcus xanthus
Sydney, N., Swain, M. T., So, J. M. T., Hoiczyk, E., Tucker, N. P. & Whitworth, D. E., 01 Aug 2021, In: Microbial Physiology. 31, 2, p. 57-66 10 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile53 Downloads (Pure) -
A genomic survey of signalling in the myxococcaceae
Whitworth, D. E. & Zwarycz, A., 06 Nov 2020, In: Microorganisms. 8, 11, 20 p., 1739.Research output: Contribution to journal › Article › peer-review
Open AccessFile65 Downloads (Pure) -
A survey of non-coding RNAs in the social and predatory myxobacterium Myxococcus xanthus DK1622
Whitworth, D. E. & Swain, M. T., 12 Oct 2020, In: Molecular Omics. 16, 5, p. 492-502 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Downloads (Pure)
Projects
- 6 Finished
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Disruption of targeted cellular processes by OMV-delivery of ncRNAs
The Joy Welch Educational Charitable Trust
01 May 2020 → 30 Apr 2022
Project: Externally funded research
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Identifying Novel Antimicrobial Compounds from Predatory Bacteria
The Joy Welch Educational Charitable Trust
01 Jun 2017 → 31 May 2018
Project: Externally funded research
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Predatory bacteria for the contorl of food pathogens
The Joy Welch Educational Charitable Trust
01 Jun 2016 → 31 May 2017
Project: Externally funded research
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Kriti Sengupta visiting fellowship: omics of 4NP degradation
01 Apr 2016 → 31 Mar 2017
Project: Externally funded research
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Aphids as agents of disease
The Joy Welch Educational Charitable Trust
01 Jun 2015 → 10 Jul 2015
Project: Externally funded research