Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Iain Chalmers is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes
Padalino, G., Celatka, C., Rienhoff Jr., H. Y., Kalin, J. H., Cole, P. A., Lassalle, D., Forde-Thomas, J., Chalmers, I., Brancale, A., Grunau, C. & Hoffmann, K., 30 Mar 2023, In: Wellcome Open Research. 8, 146, 33 p., 146.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)68 Downloads (Pure) -
Protective human IgE responses are promoted by comparable life-cycle dependent Tegument Allergen-Like expression in Schistosoma haematobium and Schistosoma mansoni infection
Oettle, R. C., Dickinson, H. A., Fitzsimmons, C. M., Sacko, M., Tukahebwa, E. M., Chalmers, I. W., Wilson, S. & Loke, P. (Editor), 25 May 2023, In: PLoS Pathogens. 19, 5, p. e1011037 20 p., e1011037.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)144 Downloads (Pure) -
Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility
White, R., Sotillo, J., Ancarola, M. E., Borup, A., Boysen, A. T., Brindley, P. J., Buzás, E. I., Cavallero, S., Chaiyadet, S., Chalmers, I. W., Cucher, M. A., Dagenais, M., Davis, C. N., Devaney, E., Duque-Correa, M. A., Eichenberger, R. M., Fontenla, S., Gasan, T. A., Hokke, C. H. & Kosanovic, M. & 22 others, , 05 Jan 2023, In: Journal of Extracellular Vesicles. 12, 1, 16 p., 12298.Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Citations (Scopus)115 Downloads (Pure) -
In silico characterisation of the complete Ly6 protein family in Fasciola gigantica supported through transcriptomics of the newly-excysted juveniles
Davey, S. D., Chalmers, I. W., Fernandez-Fuentes, N., Swain, M. T., Smith, D., Abbas Abidi, S. M., Saifullah, M. K., Raman, M., Ravikumar, G., McVeigh, P., Maule, A. G., Brophy, P. M. & Morphew, R. M., 17 Jan 2022, In: Molecular Omics. 18, 1, p. 45-56 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)91 Downloads (Pure) -
Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production
Hulme, B. J., Geyer, K. K., Forde-Thomas, J. E., Padalino, G., Phillips, D. W., Ittiprasert, W., Karinshak, S. E., Mann, V. H., Chalmers, I. W., Brindley, P. J., Hokke, C. H. & Hoffmann, K. F., 13 Jan 2022, In: PLoS Pathogens. 18, 1, 35 p., e1009828.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)192 Downloads (Pure) -
Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation
Padalino, G., El-Sakkary, N., Liu, L. J., Liu, C., Harte, D. S. G., Barnes, R. E., Sayers, E., Forde-Thomas, J., Whiteland, H., Bassetto, M., Ferla, S., Johnson, G., Jones, A. T., Caffrey, C. R., Chalmers, I., Brancale, A. & Hoffmann, K. F., 15 Dec 2021, In: European Journal of Medicinal Chemistry. 226, 19 p., 113823.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)193 Downloads (Pure) -
Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae
Gasan, T. A., Kuipers, M. E., Roberts, G. H., Padalino, G., Forde-Thomas, J. E., Wilson, S., Wawrzyniak, J., Tukahebwa, E. M., Hoffmann, K. F. & Chalmers, I. W., 18 Nov 2021, In: PLoS Neglected Tropical Diseases. 15, 11, e0009981.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Schistosoma mansoni venom allergen-like protein 6 (SmVAL6) maintains tegumental barrier function
Perally, S., Geyer, K. K., Farani, P. S. G., Chalmers, I. W., Fernandez-Fuentes, N., Maskell, D. R., Hulme, B. J., Forde-Thomas, J., Phillips, D., Farias, L. P., Collins, J. J. & Hoffmann, K. F., 01 Mar 2021, In: International Journal for Parasitology. 51, 4, p. 251-261 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)123 Downloads (Pure) -
Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities
Padalino, G., Chalmers, I. W., Brancale, A. & Hoffmann, K. F., 13 Nov 2020, In: Wellcome Open Research. 5, 37 p., 169.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)95 Downloads (Pure) -
Schistosoma mansoni venom allergen-like proteins: Phylogenetic relationships, stage-specific transcription and tissue localization as predictors of immunological cross-reactivity
Farias, L. P., Chalmers, I. W., Perally, S., Rofatto, H. K., Jackson, C. J., Brown, M., Khouri, M. I., Barbosa, M. M. F., Hensbergen, P. J., Hokke, C. H., Leite, L. C. C. & Hoffmann, K. F., 01 Jul 2019, In: International Journal for Parasitology. 49, 8, p. 593-599 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)195 Downloads (Pure) -
The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets
Whatley, K., Padalino, G., Whiteland, H., Geyer, K. K., Hulme, B. J., Chalmers, I., Forde-Thomas, J., Ferla, S., Brancale, A. & Hoffmann, K., 15 Nov 2019, In: PLoS Neglected Tropical Diseases. 13, 11, 24 p., e0007693.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)263 Downloads (Pure)
Datasets
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Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities - Underlying data
Padalino, G., Chalmers, I. W., Brancale, A. & Hoffmann, K., Figshare, 23 Jun 2020
DOI: 10.6084/m9.figshare.12473108, https://figshare.com/articles/Identification_of_6-_piperazin-1-yl_-1_3_5-triazine_as_a_chemical_scaffold_with_broad_anti-schistosomal_activities/12473108
Dataset
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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes - Supplementary tables and movies
Padalino, G., Celatka, C. A., Young Rienhoff Jr, H., Kalin, J. H., Cole, P. A., Lassalle, D., Forde-Thomas, J., Chalmers, I. W., Brancale, A., Grunau, C. & Hoffmann, K. F., Figshare, 04 Jan 2023
DOI: 10.6084/m9.figshare.21814623
Dataset
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Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities - Extended data
Padalino, G., Chalmers, I. W., Brancale, A. & Hoffmann, K., Figshare, 23 Jun 2020
DOI: 10.6084/m9.figshare.12546449, https://figshare.com/articles/Identification_of_6-_piperazin-1-yl_-1_3_5-triazine_as_a_chemical_scaffold_with_broad_anti-schistosomal_activities/12546449/2
Dataset
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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes - Supplementary Figures
Padalino, G., Celatka, C. A., Young Rienhoff Jr, H., Kalin, J. H., A Cole, P., Lassalle, D., Forde-Thomas, J., Chalmers, I. W., Brancale, A., Grunau, C. & Hoffmann, K. F., Figshare, 05 Mar 2023
DOI: 10.6084/m9.figshare.21814710
Dataset
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Press/Media
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Aberystwyth University Researchers Reveal New Findings on Nucleoproteins [Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes [version 1; peer review: 2 approved]]
Forde-Thomas, J., Hoffmann, K. & Chalmers, I.
10 Aug 2023
1 item of Media coverage
Press/Media: Media coverage
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Parasites: Past or Future
Chalmers, I. (Speaker)
17 Jun 2015Activity: Talk or presentation › Oral presentation
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National Science and Engineering Week
Chalmers, I. (Participant)
17 Apr 2015Activity: Participating in or organising an event › Festival or Exhibition
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Parasites: Past or Future talk
Chalmers, I. (Speaker)
17 Jun 2014Activity: Talk or presentation › Oral presentation
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National Science Engineering Week
Chalmers, I. (Participant)
16 Apr 2014Activity: Participating in or organising an event › Festival or Exhibition
Prizes
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Queen’s Anniversary Prize 2023
Brophy, P. (Recipient), Hamilton, J. (Recipient), Hoffmann, K. (Recipient), Jones, R. (Recipient), Chalmers, I. (Recipient), Morphew, R. (Recipient), Rinaldi, G. (Recipient), Williams, H. (Recipient) & Barber, I. (Recipient), 2023
Prize: Prize (including medals and awards)