Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Josephine Forde-Thomas is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Research output
- 18 Article
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Gut microbiota and immune profiling of microbiota-humanised versus wildtype mouse models of hepatointestinal schistosomiasis
Stark, K. A., Rinaldi, G., Costain, A., Clare, S., Tolley, C., Almeida, A., McCarthy, C., Harcourt, K., Brandt, C., Lawley, T. D., Berriman, M., MacDonald, A. S., Forde-Thomas, J. E., Hulme, B. J., Hoffmann, K. F., Cantacessi, C. & Cortés, A., 01 Dec 2024, In: Animal Microbiome. 6, 1, 36.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes
Padalino, G., Celatka, C., Rienhoff Jr., H. Y., Kalin, J. H., Cole, P. A., Lassalle, D., Forde-Thomas, J., Chalmers, I., Brancale, A., Grunau, C. & Hoffmann, K., 30 Mar 2023, In: Wellcome Open Research. 8, 146, 29 p., 146.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)70 Downloads (Pure) -
Modified Hederagenin Derivatives Demonstrate Ex Vivo Anthelmintic Activity against Fasciola hepatica
Chakroborty, A., Pritchard, D., Bouillon, M. E., Cervi, A., Kraehenbuehl, R., Wild, C., Fenn, C., Holdsworth, P. A., Capner, C., Padalino, G., Forde-Thomas, J., Payne, J., Smith, B. G., Fisher, M., Lahmann, M., Baird, M. S. & Hoffmann, K., 03 Jul 2023, In: Pharmaceutics. 15, 7, 15 p., 1869.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)103 Downloads (Pure) -
Pulmonary inflammation promoted by type-2 dendritic cells is a feature of human and murine schistosomiasis
Houlder, E. L., Costain, A. H., Nambuya, I., Brown, S. L., Koopman, J. P. R., Langenberg, M. C. C., Janse, J. J., Hoogerwerf, M. A., Ridley, A. J. L., Forde-Thomas, J. E., Colombo, S. A. P., Winkel, B. M. F., Galdon, A. A., Hoffmann, K. F., Cook, P. C., Roestenberg, M., Mpairwe, H. & MacDonald, A. S., 01 Dec 2023, In: Nature Communications. 14, 1, 12 p., 1863.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)164 Downloads (Pure) -
Small Molecule Ligands of the BET-like Bromodomain, SmBRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development
Schiedel, M., McArdle, D. J. B., Padalino, G., Chan, A. K. N., Forde-Thomas, J., McDonough, M., Whiteland, H., Beckmann, M., Cookson, R., Hoffmann, K. F. & Conway, S. J., 14 Dec 2023, In: Journal of Medicinal Chemistry. 66, 23, p. 15801-15822 22 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Using ChEMBL to Complement Schistosome Drug Discovery
Padalino, G., Coghlan, A., Pagliuca, G., Forde-Thomas, J., Berriman, M. & Hoffmann, K., 28 Apr 2023, In: Pharmaceutics. 15, 5, 26 p., 1359.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)46 Downloads (Pure) -
Flukicidal effects of abietane diterpenoid derived analogues against the food borne pathogen Fasciola hepatica.
Chakroborty, A., Pritchard, D., Bouillon, M. E., Cervi, A., Cookson, A., Wild, C., Fenn, C., Payne, J., Holdsworth, P., Capner, C., O'Neill, J., Padalino, G., Forde-Thomas, J., Gupta, S., Smith, B. G., Fisher, M., Lahmann, M., Baird, M. S. & Hoffmann, K. F., 01 Sept 2022, In: Veterinary Parasitology. 309, 9 p., 109766.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)98 Downloads (Pure) -
Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production
Hulme, B. J., Geyer, K. K., Forde-Thomas, J. E., Padalino, G., Phillips, D. W., Ittiprasert, W., Karinshak, S. E., Mann, V. H., Chalmers, I. W., Brindley, P. J., Hokke, C. H. & Hoffmann, K. F., 13 Jan 2022, In: PLOS Pathogens. 18, 1, 35 p., e1009828.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)137 Downloads (Pure) -
Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation
Padalino, G., El-Sakkary, N., Liu, L. J., Liu, C., Harte, D. S. G., Barnes, R. E., Sayers, E., Forde-Thomas, J., Whiteland, H., Bassetto, M., Ferla, S., Johnson, G., Jones, A. T., Caffrey, C. R., Chalmers, I., Brancale, A. & Hoffmann, K. F., 15 Dec 2021, In: European Journal of Medicinal Chemistry. 226, 19 p., 113823.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)153 Downloads (Pure) -
Plasmacytoid Dendritic Cells Facilitate Th Cell Cytokine Responses throughout Schistosoma mansoni Infection
Webb, L. M., Phythian-Adams, A. T., Costain, A. H., Brown, S. L., Lundie, R. J., Forde-Thomas, J., Cook, P. C., Jackson-Jones, L. H., Marley, A. K., Smits, H. H., Hoffmann, K. F., Tait Wojno, E. D. & MacDonald, A. S., 31 Aug 2021, In: ImmunoHorizons. 5, 8, p. 721-732 12 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae
Gasan, T. A., Kuipers, M. E., Roberts, G. H., Padalino, G., Forde-Thomas, J. E., Wilson, S., Wawrzyniak, J., Tukahebwa, E. M., Hoffmann, K. F. & Chalmers, I. W., 18 Nov 2021, In: PLoS Neglected Tropical Diseases. 15, 11, e0009981.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus)
Datasets
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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes - Supplementary tables and movies
Padalino, G., Celatka, C. A., Young Rienhoff Jr, H., Kalin, J. H., Cole, P. A., Lassalle, D., Forde-Thomas, J., Chalmers, I. W., Brancale, A., Grunau, C. & Hoffmann, K. F., figshare, 04 Jan 2023
DOI: 10.6084/m9.figshare.21814623
Dataset
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Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes - Supplementary Figures
Padalino, G., Celatka, C. A., Young Rienhoff Jr, H., Kalin, J. H., A Cole, P., Lassalle, D., Forde-Thomas, J., Chalmers, I. W., Brancale, A., Grunau, C. & Hoffmann, K. F., figshare, 05 Mar 2023
DOI: 10.6084/m9.figshare.21814710
Dataset
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Press/Media
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Aberystwyth University Researchers Reveal New Findings on Nucleoproteins [Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes [version 1; peer review: 2 approved]]
10 Aug 2023
1 item of Media coverage
Press/Media: Media coverage