Research output per year
Research output per year
Personal profile
Research interests
Our laboratory studies post-exponential phase gene expression in several Gram-positive bacteria, including Bacillus and Clostridium. Recent work on dormancy in Micrococcus luteus led to the discovery of the Rpf family of bacterial growth factors found throughout the actinobacteria (e.g. mycobacteria, streptomycetes). We are currently exploring the mechanism of actions of these secreted bacterial growth factors and their potential applications for TB protection and therapy.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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- 1 Similar Profiles
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A Tool for Multiple Targeted Genome Deletions that Is Precise, Scar-Free, and Suitable for Automation.
Aubrey, W., Riley, M., Young, M., King, R. D., Oliver, S. G. & Clare, A., 02 Dec 2015, In: PLoS One. 10, 12, e0142494.Research output: Contribution to journal › Article › peer-review
Open AccessFile209 Downloads (Pure) -
Surviving the heat: Heterogeneity of response in Saccharomyces cerevisiae provides insight into thermal damage to the membrane
Guyot, S., Gervais, P., Young, M., Winckler, P., Dumont, J. & Davey, H., 14 May 2015, In: Environmental Microbiology. 17, 8, p. 2982-2992 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile48 Citations (Scopus)80 Downloads (Pure) -
Cyclic Amp-Dependent Resuscitation of Dormant Mycobacteria by Exogenous Free Fatty Acids
Shleeva, M., Goncharenko, A., Kudykina, Y., Young, D., Young, M., Kaprelyants, A. & Tailleux, L. (Editor), 23 Dec 2013, In: PLoS One. 8, 12, e82914.Research output: Contribution to journal › Article › peer-review
Open AccessFile54 Citations (Scopus)311 Downloads (Pure) -
PD5: a general purpose library for primer design software
Riley, M. C., Aubrey, W., Young, M. & Clare, A., 21 Nov 2013, In: PLoS One. 8, 11, e80156.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)214 Downloads (Pure) -
Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds
Bilsland, E., Sparkes, A. C., Williams, K. S., Moss, H. J., de Clare, M., Pir, P., Rowland, J., Aubrey, W., Pateman, R., Young, M., Carrington, M., King, R. D. & Oliver, S. G., 27 Feb 2013, In: Open Biology. 3, 2, 14 p., 120158.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)185 Downloads (Pure) -
Zero Forcing, Linear and Quantum Controllability for Systems Evolving on Networks
Burgarth, D., D'Alessandro, D., Hogben, L., Severini, S. & Young, M., Sept 2013, In: IEEE Transactions on Automatic Control. 58, 9, p. 2349-2354 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile52 Citations (Scopus)189 Downloads (Pure) -
Multiple orphan histidine kinases interact directly with Spo0A to control the initiation of endospore formation in Clostridium acetobutylicum
Heap, J. P., Young, D. I., Dago, A. E., Minton, N. P., Hoch, J. A., Young, M. & Steiner, E., 14 Mar 2011, In: Molecular Microbiology. 80, 3, p. 641-654 14 p.Research output: Contribution to journal › Article › peer-review
116 Citations (Scopus) -
Possible interactions between bacterial diversity, microbial activity and supraglacial hydrology of cryoconite holes in Svalbard
Edwards, A., Anesio, A. M., Edwards Rassner, S. M., Sattler, B., Hubbard, B. P., Perkins, W. T., Young, M. & Griffith, G. W., 01 Jan 2011, In: ISME Journal. 5, 1, p. 150-160 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile149 Citations (Scopus)99 Downloads (Pure) -
An Integrated Laboratory Robotic System for Autonomous Discovery of Gene Function
Sparkes, A. C., King, R. D., Aubrey, W., Benway, M., Byrne, E. L., Clare, A. J., Liakata, M., Markham, M., Whelan, K. E., Young, M. & Rowland, J., 01 Feb 2010, In: Journal of The Association for Laboratory Automation. 15, 1, p. 33-40 8 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Genome sequence of the Fleming strain of Micrococcus luteus, a simple free-living actinobacterium
Young, M., Artsatbanov, V., Beller, H. R., Chandra, G., Chater, K. F., Dover, L. G., Goh, E.-B., Kahan, T., Kaprelyants, A. S., Kyrpides, N., Lapidus, A., Lowry, S. R., Lykidis, A., Mahillon, J., Markowitz, V., Mavromatis, K., Mukamolova, G. V., Oren, A., Rokem, J. S. & Smith, M. C. M. & 2 others, , 01 Feb 2010, In: Journal of Bacteriology. 192, 3, p. 841-860 20 p.Research output: Contribution to journal › Article › peer-review
60 Citations (Scopus) -
Structural changes and cellular localization of resuscitation promoting factor in environmental isolates of Micrococcus luteus
Koltunov, V., Greenblatt, C. L., Goncharenko, A. V., Demina, G. R., Klein, B. Y., Young, M. & Kaprelyants, A. S., 01 Feb 2010, In: Microbial Ecology. 59, 2, p. 296-310 15 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus)
Projects
- 3 Finished
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Cleavage Specificityof the Rpf proteins
Young, M. (PI)
01 Apr 2011 → 31 Aug 2011
Project: Externally funded research
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The roles of prokaryotic dormancy, resuscitation and survival in the ecology of human skin biofilms (CASE award)
Young, M. (PI)
Unilever UK Central Resources Ltd
01 Dec 2007 → 30 Nov 2010
Project: Externally funded research
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CASE Studentship The roles of prokarvotic dormancy, recusitation and survival in the ecology of human skin biofilms
Young, M. (PI)
Biotechnology and Biological Sciences Research Council
01 Oct 2007 → 30 Sept 2011
Project: Externally funded research