Personal profile
Profile
My primary project is on the development of deep learning models and computer vision approaches for quantifying drug response phenotypes in Schistosoma mansoni.
Research interests
- Development of computer vision models for S. mansoni drug discovery
- Transcriptomic assembly and annotation
- Bioinformatics approaches to support drug discovery
Responsibilities
- Writer for the BCHC website : https://bchc.aber.ac.uk/
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger -
SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Research output
- 6 Article
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Hedera helix-derived α−hederin (IVL-11) demonstrates both ex vivo and in vivo flukicidal activities against Fasciola hepatica
Davey, S. D., Chakroborty, A., Payne, J., Burgess, A. M. G., Hulme, B. J., Bouillon, M. E., Thomas, D. A., Cervi, A., Padalino, G., Cookson, A., Al-Najjar, A., Frame, L., Fenn, C., Holdsworth, P., Lahmann, M., McNally, V., Fisher, M., Baird, M. S. & Hoffmann, K. F., 31 Mar 2026, In: Biomedicine & Pharmacotherapy. 196, 13 p., 119123.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
In vitro sexual dimorphism establishment in schistosomes
Pichon, R., Lotkowska, M. E., Bulathsinghalage, J. L. D., McMath, M., Evans, M., Hulme, B. J., Ambridge, K., Sankaranarayanan, G., Kershenbaum, S., Davey, S. D., Forde-Thomas, J. E., Hoffmann, K. F., Berriman, M. & Rinaldi, G., 20 Apr 2026, (Accepted/In press) In: eLife.Research output: Contribution to journal › Article › peer-review
Open Access -
Use of a cytochrome P450 humanized mouse model to refine schistosomiasis drug discovery
Davey, S. D., Forde-Thomas, J. E., Hulme, B. J., Lees, K., Costain, A. H., Evans, M., Rinaldi, G., Frame, L., Stojanovski, L., Simeons, F. R. C., Tavendale, A., MacLeod, A. K., Pichon, R., Lee, Y.-H., Polak, O., Chalmers, I. W., Dankwa, B., Odhiambo, B. K., Guimaraes, V. H. & Hegarty, M. & 8 others, , 14 Apr 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 15, 12 p., e2600197123.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Anthelmintic evaluation of triterpenes derived from conifers (family Pinaceae) on the digenean parasite Fasciola hepatica
Chakroborty, A., Dankwa, B., Crusco, A., Forde-Thomas, J. E., Abeysekara, S., Kiwanuka, Z., Ley, M., Davey, S. D., Hollinshead, J., Bartholomew, B., Wild, C., Fenn, C., Thomas, D. A., Holdsworth, P., Fisher, M., Baird, M. S., Nash, R. J. & Hoffmann, K. F., 30 Sept 2025, In: Fitoterapia. 185, 11 p., 106762.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)10 Downloads (Pure) -
In silico characterisation of the complete Ly6 protein family in Fasciola gigantica supported through transcriptomics of the newly-excysted juveniles
Davey, S. D., Chalmers, I. W., Fernandez-Fuentes, N., Swain, M. T., Smith, D., Abbas Abidi, S. M., Saifullah, M. K., Raman, M., Ravikumar, G., McVeigh, P., Maule, A. G., Brophy, P. M. & Morphew, R. M., 17 Jan 2022, In: Molecular Omics. 18, 1, p. 45-56 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)105 Downloads (Pure) -
Evidence of Immune Modulators in the Secretome of the Equine Tapeworm Anoplocephala perfoliata
Wititkornkul, B., Hulme, B. J., Tomes, J. J., Allen, N. R., Davis, C. N., Davey, S. D., Cookson, A. R., Phillips, H. C., Hegarty, M. J., Swain, M. T., Brophy, P. M., Wonfor, R. E. & Morphew, R. M., 20 Jul 2021, In: Pathogens. 10, 7, 30 p., e912.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)230 Downloads (Pure)
Thesis
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Repositioning histone modifying enzyme (HME) inhibitors as next-generation flukicides
Davey, S. (Author), Hoffmann, K. (Supervisor) & Chalmers, I. (Supervisor), 2024Student thesis: Doctoral Thesis › Doctor of Philosophy
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Accelerating pre-clinical drug discovery for schistosomiasis
Hoffmann, K. (Project Lead), Davey, S. (Research and Innovation Associate), Hulme, B. (Research and Innovation Associate), Lees, K. (Research and Innovation Associate) & Evans, M. (Technician)
01 Jan 2026 → 31 Dec 2031
Project: Externally funded research
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MoA: MoA 13400A-01: 2-month Extension
Hoffmann, K. (Project Lead), Davey, S. (Research and Innovation Associate), Forde-Thomas, J. (Research and Innovation Associate), Evans, M. (Technician) & Hulme, B. (Technician)
01 Apr 2025 → 31 May 2025
Project: Externally funded research