Research output per year
Research output per year
- 1 - 50 out of 53 results
Search results
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2023
CM2D3: Furnishing the Human Interactome with Structural Models of Protein Complexes Derived by Comparative Modeling and Docking
Mirela Bota, P., Hernandez, A. C., Segura, J., Gallego, O., Oliva, B. & Fernandez-Fuentes, N., 15 Jul 2023, In: Journal of Molecular Biology. 435, 14, 168055.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Downloads (Pure) -
2022
Callus Induction from Diverse Explants and Genotypes Enables Robust Transformation of Perennial Ryegrass (Lolium perenne L.)
Grogg, D., Rohner, M., Yates, S., Manzanares, C., Bull, S. E., Dalton, S., Bosch, M., Studer, B. & Broggini, G. A. L., 05 Aug 2022, In: Plants. 11, 15, 19 p., e2054.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Downloads (Pure) -
Forage grass growth under future climate change scenarios affects fermentation and ruminant efficiency
Hart, E. H., Christofides, S. R., Davies, T. E., Rees Stevens, P., Creevey, C. J., Müller, C. T., Rogers, H. J. & Kingston-smith, A. H., 01 Dec 2022, In: Scientific Reports. 12, 1, 14 p., 4454.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Downloads (Pure) -
In silico characterisation of the complete Ly6 protein family in Fasciola gigantica supported through transcriptomics of the newly-excysted juveniles
Davey, S. D., Chalmers, I. W., Fernandez-Fuentes, N., Swain, M. T., Smith, D., Abbas Abidi, S. M., Saifullah, M. K., Raman, M., Ravikumar, G., McVeigh, P., Maule, A. G., Brophy, P. M. & Morphew, R. M., 17 Jan 2022, In: Molecular Omics. 18, 1, p. 45-56 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Downloads (Pure) -
2021
A comparison of shared patterns of differential gene expression and gene ontologies in response to water-stress in roots and leaves of four diverse genotypes of Lolium and Festuca spp. temperate pasture grasses
Fu, Y., Thomas, A., Gasior, D., Harper, J., Gay, A., Jones, C., Hegarty, M., Asp, T., Fradera-Sola, A., Armstead, I. & Fernandez-Fuentes, N., 08 Apr 2021, In: PLoS One. 16, 4, 21 p., e0249636.Research output: Contribution to journal › Article › peer-review
Open AccessFile50 Downloads (Pure) -
A new genome allows the identification of genes associated with natural variation in aluminium tolerance in Brachiaria grasses
Worthington, M., Perez, J., Mussurova, S., Silva-Cordoba, A., Castiblanco, V., Arango, J., Jones, C., Fernandez Fuentes, N., Skot, L., Dyer, S., Tohme, J., Di Palma, F., Arango, J., Armstead, I. & De Vega, J., 02 Feb 2021, In: Journal of Experimental Botany. 72, 2, p. 302-319 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile107 Downloads (Pure) -
Mechanical stimulation in wheat triggers age- and dose-dependent alterations in growth, development and grain characteristics
Hindhaugh, R., Donnison, I. & Bosch, M., 08 Oct 2021, In: Annals of Botany. 128, 5, p. 589-603 15 p., mcab070.Research output: Contribution to journal › Article › peer-review
Open AccessFile84 Downloads (Pure) -
Microbiomes attached to fresh perennial ryegrass are temporally resilient and adapt to changing ecological niches
Huws, S. A., Edwards, J. E., Lin, W., Rubino, F., Alston, M., Swarbreck, D., Caim, S., Stevens, P. R., Pachebat, J., Won, M. Y., Oyama, L. B., Creevey, C. J. & Kingston-Smith, A. H., 01 Dec 2021, In: Microbiome. 9, 1, 17 p., 143.Research output: Contribution to journal › Article › peer-review
Open AccessFile153 Downloads (Pure) -
Schistosoma mansoni venom allergen-like protein 6 (SmVAL6) maintains tegumental barrier function
Perally, S., Geyer, K. K., Farani, P. S. G., Chalmers, I. W., Fernandez-Fuentes, N., Maskell, D. R., Hulme, B. J., Forde-Thomas, J., Phillips, D., Farias, L. P., Collins, J. J. & Hoffmann, K. F., 01 Mar 2021, In: International Journal for Parasitology. 51, 4, p. 251-261 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile45 Downloads (Pure) -
2020
A Functional Kinase Is Necessary for Cyclin-Dependent Kinase G1 (CDKG1) to Maintain Fertility at High Ambient Temperature in Arabidopsis
Nibau, C., Dadarou, D., Kargios, N., Mallioura, A., Fernandez-Fuentes, N., Cavallari, N. & Doonan, J. H., 10 Nov 2020, In: Frontiers in Plant Science. 11, 12 p., 586870.Research output: Contribution to journal › Article › peer-review
Open AccessFile157 Downloads (Pure) -
A route to decreasing N pollution from livestock: Use of Festulolium hybrids improves efficiency of N flows in rumen simulation fermenters
Kamau, S., Belanche Gracia, A., Davies, T., Rees Stevens, P., Humphreys, M. & Kingston-Smith, A., 25 Aug 2020, In: Food and Energy Security. 9, 3, 15 p., e209.Research output: Contribution to journal › Article › peer-review
Open AccessFile63 Downloads (Pure) -
CDKG1 Is Required for Meiotic and Somatic Recombination Intermediate Processing in Arabidopsis
Nobre Nibau, C., Lloyd, A. H., Dadarou, D., Betekhtin, A., Tsilimigka, F., Phillips, D. & Doonan, J., 01 Apr 2020, In: Plant Cell. 32, 4, p. 1308-1322 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile98 Downloads (Pure) -
Cupid, a cell permeable peptide derived from amoeba, capable of delivering GFP into a diverse range of species
Fenton, D., Phillips, D., Maddison, A., H. George, C., Ryves, J. & D. Jones, H., 13 Aug 2020, In: Scientific Reports. 10, 1, 11 p., 13725.Research output: Contribution to journal › Article › peer-review
Open AccessFile104 Downloads (Pure) -
RNA-based biocontrol compounds: Current status and perspectives to reach the market
Taning, C. N. T., Arpaia, S., Christiaens, O., Dietz-Pfeilstetter, A., Jones, H., Mezzetti, B., Sabbadini, S., Hoen-Sorteberg, H-G. O., Sweet, J., Ventura, V. & Smagghe, G., 11 Feb 2020, In: Pest Management Science. 76, 3, p. 841-845 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile91 Citations (SciVal)443 Downloads (Pure) -
RNAi: What is its position in agriculture?
Mezzetti, B., Smagghe, G., Arpaia, S., Christiaens, O., Dietz-Pfeilstetter, A., Jones, H., Kostov, K., Sabbadini, S., Opsahl-Sorteberg, H. G., Ventura, V., Taning, C. N. T. & Sweet, J., 01 Sept 2020, In: Journal of Pest Science. 93, 4, p. 1125-1130 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile175 Downloads (Pure) -
The Isolation and Genome Sequencing of Five Novel Bacteriophages From the Rumen Active Against Butyrivibrio fibrisolvens
Friedersdorff, J. C. A., Kingston-Smith, A. H., Pachebat, J. A., Cookson, A. R., Rooke, D. & Creevey, C. J., 14 Jul 2020, In: Frontiers in Microbiology. 11, 13 p., 1588.Research output: Contribution to journal › Article › peer-review
Open AccessFile68 Downloads (Pure) -
2019
Allele frequency changes provide evidence for selection and identification of candidate loci for survival in red clover (Trifolium pratense L)
Ergon, Å., Skøt, L., Sæther, V. E. & Rognli, O-A., 11 Jun 2019, In: Frontiers in Plant Science. 10, 718.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (SciVal)148 Downloads (Pure) -
Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription
Sharma, P., Lioutas, A., Fernandez-Fuentes, N., Quilez, J., Carbonell-Caballero, J., Wright, R. H. G., Di Vona, C., Le Dily, F., Schüller, R., Eick, D. & Oliva, B., 03 Jan 2019, In: Molecular Cell. 73, 1, p. 84-96.e7 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Citations (SciVal)137 Downloads (Pure) -
Breeding progress and preparedness for mass‐scale deployment of perennial lignocellulosic biomass crops switchgrass, miscanthus, willow and poplar
Clifton-Brown, J., Harfouche, A., Casler, M., Jones, H., MacAlpine, W. J., Murphy-Bokern, D., Smart, L., Adler, A., Ashman, C. R., Awty-Carroll, D., Bastien, C., Bopper, S., Botnari, V., Brancourt-Hulmel, M., Chen, Z., Clark, L., Cosentino, S., Dalton, S., Davey, C., Dolstra, O., & 39 others, 01 Jan 2019, In: GCB Bioenergy. 11, 1, p. 118-151 34 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile93 Citations (SciVal)232 Downloads (Pure) -
Colombia's cyberinfrastructure for biodiversity: Building data infrastructure in emerging countries to foster socioeconomic growth
de Vega, J., Davey, R. P., Duitama, J., Escobar, D., Cristancho‐ardila, M. A., Etherington, G. J., Minotto, A., Arenas‐Suarez, N. E., Pineda‐Cardenas, J. D., Correa‐Alvarez, J., Camargo Rodriguez, A. V., Haerty, W., Mallarino‐Robayo, J. P., Barreto‐Hernandez, E., Muñoz‐Torres, M., Fernandez Fuentes, N. & Di Palma, F., 22 Dec 2019, (E-pub ahead of print) In: Plants, People, Planet.Research output: Contribution to journal › Article › peer-review
Open AccessFile84 Downloads (Pure) -
Differential gene expression and gene ontologies associated with increasing water-stress in leaf and root transcriptomes of perennial ryegrass (Lolium perenne)
Fradera-Sola, A., Thomas, A., Gasior, D., Harper, J., Hegarty, M., Armstead, I. & Fernandez Fuentes, N., 30 Jul 2019, In: PLoS One. 14, 7, e0220518.Research output: Contribution to journal › Article › peer-review
Open AccessFile142 Downloads (Pure) -
Future-proofing regulation for rapidly changing biotechnologies
Jones, H., 01 Aug 2019, In: Transgenic Research. 28, Suppl 2, p. 107-110 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile165 Downloads (Pure) -
Instability of Alien Chromosome Introgressions in Wheat Associated with Improper Positioning in the Nucleus
Perničková, K., Koláčková, V., Lukaszewski, A. J., Fan, C., Vrána, J., Duchoslav, M., Jenkins, G., Phillips, D., Šamajová, O., Sedlářová, M., Šamaj, J., Doležel, J. & Kopecký, D., 22 Mar 2019, In: International Journal of Molecular Sciences. 20, 6, 1448.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (SciVal)134 Downloads (Pure) -
Integrating a newly developed BAC-based physical mapping resource for Lolium perenne with a genome-wide association study across a L. Perenne European ecotype collection identifies genomic contexts associated with agriculturally important traits
Harper, J., de Vega, J., Swain, S., Heavens, D., Gasior, D., Thomas, A., Evans, C., Lovatt, A., Lister, S., Thorogood, D., Skot, L., Hegarty, M., Blackmore, T., Kudrna, D., Byrne, S., Asp, T., Powell, W., Fernandez-Fuentes, N. & Armstead, I., 08 May 2019, In: Annals of Botany. 123, 6, p. 977-992 16 p., mcy230.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (SciVal)126 Downloads (Pure) -
Recovery of 2R.2Sk Triticale-Aegilops kotschyi Robertsonian Chromosome Translocations
Ulaszewski, W., Belter, J., Wiśniewska, H., Szymczak, J., Skowrońska, R., Phillips, D. & Kwiatek, M. T., 17 Oct 2019, In: Agronomy. 9, 10, 646.Research output: Contribution to journal › Article › peer-review
Open AccessFile105 Downloads (Pure) -
Transcriptional and Metabolomic Analyses Indicate that Cell Wall Properties are Associated with Drought Tolerance in Brachypodium distachyon
Lenk, I., Fisher, L., Vickers, M., Akinyemi, A., Didion, T., Swain, M., Sig Jensen, C., Mur, L. & Bosch, M., 10 Apr 2019, In: International Journal of Molecular Sciences. 20, 7, 1758.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (SciVal)131 Downloads (Pure) -
2018
A cytological approach to study meiotic recombination and chromosome dynamics of Arabidopsis thaliana male meiocytes in three dimensions
Hurel, A., Phillips, D., Vrielynck, N., Mézard, C., Grelon, M. & Christophorou, N., 31 Jul 2018, In: Plant Journal. 95, 2, p. 385-396 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (SciVal)138 Downloads (Pure) -
An investigation of genotype-phenotype association in a festulolium forage grass population containing genome-spanning Festuca pratensis chromosome segments in a Lolium perenne background
Harper, J., Gasior, D., Mathews, R., Thomas, A., Evans, C., King, J., King, I., Humphreys, M. & Armstead, I., 14 Nov 2018, In: PLoS One. 13, 11, e0207412.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (SciVal)161 Downloads (Pure) -
Anthropogenic Impacts on Meiosis in Plants
Fuchs, L. K., Jenkins, G. & Phillips, D., 28 Sept 2018, In: Frontiers in Plant Science. 9, 01429.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (SciVal)142 Downloads (Pure) -
Assessment of genetically modified soybean MON 87751 for food and feed uses under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2014‐121)
Naegeli, H., Birch, A. N., Casacuberta, J., De Schrijver, A., Gralak, M. A., Jones, H., Manachini, B., Messéan, A., Nielsen, E. E., Nogué, F., Robaglia, C., Rostoks, N., Sweet, J., Tebbe, C., Visioli, F., Wal, J., Álvarez, F., Ardizzone, M., Fernandez Dumont, A., Gómez Ruiz, J. Á., & 2 others, 01 Aug 2018, In: EFSA Journal. 16, 8, e05346.Research output: Contribution to journal › Article › peer-review
Open AccessFile131 Downloads (Pure) -
A Welcome Proposal to Amend the GMO Legislation of the EU
Eriksson, D., Harwood, W., Hofvander, P., Jones, H., Rogowsky, P., Stöger, E. & Visser, R. G. F., 01 Nov 2018, In: Trends in Biotechnology. 36, 11, p. 1100-1103 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Citations (SciVal)132 Downloads (Pure) -
B chromosomes are associated with redistribution of genetic recombination towards lower-recombination chromosomal regions in perennial ryegrass
Harper, J., Phillips, D., Thomas, A., Gasior, D., Evans, C., Powell, W., King, J., King, I. P., Jenkins, G. & Armstead, I., 21 Mar 2018, In: Journal of Experimental Botany. 69, 8Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (SciVal)88 Downloads (Pure) -
Cell Wall Epitopes and Endoploidy as Reporters of Embryogenic Potential in Brachypodium Distachyon Callus Culture
Betekhtin, A., Rojek, M., Nowak, K., Pinski, A., Milewska-Hendel, A., Kurczynska, E., Doonan, J. & Hasterok, R., 29 Nov 2018, In: International Journal of Molecular Sciences. 19, 12, 3811.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (SciVal)178 Downloads (Pure) -
Draft Genome Assemblies of Xylose-Utilizing Candida tropicalis and Candida boidinii with Potential Application in Biochemical and Biofuel Production
Somani, A., Smith, D., Hegarty, M., Fernandez-Fuentes, N., Ravella, S., Gallagher, J. & Bryant, D., 15 Feb 2018, In: Genome Announcements. 6, 7, e01594-17.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (SciVal)132 Downloads (Pure) -
Introgression of Aegilops speltoides segments in Triticum aestivum and the effect of the gametocidal genes
King, J., Grewal, S., Yang, C., Hubbart Edwards, S., Scholefield, D., Ashling, S., Harper, J., Allen, A., Edwards, K. J., Burridge, A. & King, I. P., 23 Jan 2018, In: Annals of Botany. 121, 2, p. 229-240 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Citations (SciVal)126 Downloads (Pure) -
Methyl-CpG-binding (SmMBD2/3) and chromobox (SmCBX) proteins are required for neoblast proliferation and oviposition in the parasitic blood fluke Schistosoma mansoni
Geyer, K., Munshi, S. E., Whiteland, H., Fernandez-Fuentes, N., Phillips, D. & Hoffmann, K., 28 Jun 2018, In: PLOS Pathogens. 14, 6, e1007107.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (SciVal)158 Downloads (Pure) -
Polyomic tools for an emerging livestock parasite, the rumen fluke Calicophoron daubneyi; identifying shifts in rumen functionality
Huson, K. M., Morphew, R., Allen, N., Hegarty, M., Worgan, H., Girdwood, S., Jones, E. L., Phillips, H., Vickers, M., Swain, M., Smith, D., Kingston-Smith, A. & Brophy, P., 04 Dec 2018, In: Parasites & Vectors. 11, 1, 22 p., 617.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (SciVal)333 Downloads (Pure) -
Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment
Quevedo, C. E., Cruz-Migoni, A., Bery, N., Miller, A., Tanaka, T., Petch, D., Bataille, C. J. R., Lee, L. Y. W., Fallon, P. S., Tulmin, H., Ehebauer, M. T., Fernandez Fuentes, N., Russell, A. J., Carr, S. B., Phillips, S. E. V. & Rabbitts, T. H., 09 Aug 2018, In: Nature Communications. 9, 3169.Research output: Contribution to journal › Article › peer-review
Open AccessFile205 Downloads (Pure) -
Smart gene edits need tailored regulations
Jones, H., 01 Jan 2018, In: Journal of Cereal Science. 77, p. A1-A2Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (SciVal)64 Downloads (Pure) -
Technical Note on the quality of DNA sequencing for the molecular characterisation of genetically modified plants
Casacuberta, J., Nogué, F., Naegeli, H., Birch, A. N., De Schrijver, A., Gralak, M. A., Guerche, P., Manachini, B., Messéan, A., Nielsen, E. E., Robaglia, C., Rostoks, N., Sweet, J., Tebbe, C., Visioli, F., Wal, J-M., Moxon, S., Schneeberger, K., Federici, S., Ramon, M., & 2 others, 11 Jul 2018, (E-pub ahead of print) In: EFSA Journal. 16, 7, e05345.Research output: Contribution to journal › Article
Open AccessFile15 Citations (SciVal)102 Downloads (Pure) -
2017
Buwchitin: A Ruminal Peptide with Antimicrobial Potential against Enterococcus faecalis
Oyama, L. B., Crochet, J-A., Edwards, J. E., Girdwood, S., Cookson, A., Fernandez-Fuentes, N., Hilpert, K., Golyshin, P. N., Golyshina, O. V., Privé, F., Hess, M., Mantovani, H. C., Creevey, C. & Huws, S., 12 Jul 2017, In: Frontiers in Chemistry. 5, 51.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (SciVal)143 Downloads (Pure) -
Defining genetic and chemical diversity in wheat grain by 1H-NMR spectroscopy of polar metabolites
Shewry, P. R., Corol, D. I., Jones, H., Beale, M. H. & Ward, J. L., 24 Feb 2017, In: Molecular Nutrition and Food Research. 61, 7, 9 p., 1600807.Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (SciVal)161 Downloads (Pure) -
Genetic and functional characterization of disease associations explains comorbidity
Rubio-Perez, C., Guney, E., Aguilar, D., Piñero, J., Garcia-Garcia, J., Iadarola, B., Sanz, F., Fernandez-Fuentes, N., Furlong, L. I. & Oliva, B., 01 Dec 2017, In: Scientific Reports. 7, 1, 6207.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (SciVal)119 Downloads (Pure) -
Genetic engineering of grass cell wall polysaccharides for biorefining: Engineering grass cell wall polysaccharides
Bhatia, R., Gallagher, J., Gomez, L. D. & Bosch, M., 01 Sept 2017, In: Plant Biotechnology Journal. 15, 9, p. 1071-1092Research output: Contribution to journal › Article › peer-review
Open AccessFile43 Citations (SciVal)151 Downloads (Pure) -
Guidance for the risk assessment of the presence at low level of genetically modified plant material in imported food and feed under Regulation (EC) No 1829/2003
Naegeli, H., Birch, A. N., Casacuberta, J., De Schrijver, A., Gralak, M. A., Guerche, P., Jones, H., Manachini, B., Messéan, A., Nielsen, E. E., Nogué, F., Robaglia, C., Rostoks, N., Sweet, J., Tebbe, C., Visioli, F., Wal, J., Devos, Y., Fernandez Dumont, A., Lanzoni, A., & 3 others, 01 Nov 2017, In: EFSA Journal. 15, 11Research output: Contribution to journal › Article › peer-review
Open AccessFile106 Downloads (Pure) -
iFrag: A Protein-Protein Interface Prediction Server Based on Sequence Fragments
Garcia-Garcia, J., Valls-Comamala, V., Guney, E., Andreu, D., Muñoz, F. J., Fernandez-Fuentes, N. & Oliva, B., 03 Feb 2017, In: Journal of Molecular Biology. 429, 3, p. 382-389 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Citations (SciVal)90 Downloads (Pure) -
Increased SBPase activity improves photosynthesis and grain yield in wheat grown in greenhouse conditions
Driever, S. M., Simkin, A. J., Alotaibi, S., Fisk, S. J., Madgwick, P. J., Sparks, C. A., Jones, H., Lawson, T., Parry, M. A. J. & Raines, C. A., 14 Aug 2017, In: Philosophical Transactions B: Biological Sciences. 372, 1730, 10 p., 20160384.Research output: Contribution to journal › Article › peer-review
Open AccessFile164 Citations (SciVal)150 Downloads (Pure) -
Judge breeding techniques on process not product
Jones, H., 2017, Farm Business, p. 10-10 1 p.Research output: Contribution to specialist publication › Article
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On the mechanisms of protein interactions: predicting their affinity from unbound tertiary structures
Marín-López, M. A., Planas-Iglesias, J., Aguiree-Plans, J., Bonet, J., Garcia-Garcia, J., Fernandez-Fuentes, . N. & Oliva, B., 27 Sept 2017, In: Bioinformatics. 34, 4, p. 592-598 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (SciVal)102 Downloads (Pure) -
Potential impact of genome editing in world agriculture
Martinez-Fortun, J., Phillips, D. & Jones, H., 10 Nov 2017, In: Emerging Topics in Life Sciences. 1, 2, p. 117-133 16 p., 2.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Citations (SciVal)123 Downloads (Pure)