Research output per year
Research output per year
Project Details
| Status | Finished |
|---|---|
| Effective start/end date | 10 Jun 2010 → 09 Jun 2013 |
Funding
- Biotechnology and Biological Sciences Research Council (BB/H009256/1): £285,137.39
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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Research output
- 14 Article
-
In silico characterisation of the complete Ly6 protein family in Fasciola gigantica supported through transcriptomics of the newly-excysted juveniles
Davey, S. D., Chalmers, I. W., Fernandez-Fuentes, N., Swain, M. T., Smith, D., Abbas Abidi, S. M., Saifullah, M. K., Raman, M., Ravikumar, G., McVeigh, P., Maule, A. G., Brophy, P. M. & Morphew, R. M., 17 Jan 2022, In: Molecular Omics. 18, 1, p. 45-56 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)74 Downloads (Pure) -
X-ray structure of Fasciola hepatica Sigma class glutathione transferase 1 reveals a disulfide bond to support stability in gastro-intestinal environment
Line, K., Isupov, M. N., LaCourse, E. J., Cutress, D., Morphew, R., Brophy, P. & Littlechild, J. A., 01 Dec 2019, In: Scientific Reports. 9, 1, 902.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)187 Downloads (Pure) -
Calmodulin disruption impacts growth and motility in juvenile liver fluke
McCammick, E., McVeigh, P., McCusker, P., Timson, D., Morphew, R., Brophy, P., Marks, N., Mousley, A. & Maule, A., 27 Jan 2016, In: Parasites & Vectors. 9, N/A, 13 p., 46.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)173 Downloads (Pure) -
Exploring and Expanding the Fatty-Acid-Binding Protein Superfamily in Fasciola Species
Morphew, R., Wilkinson, T., MacKintosh, N., Jahndel, V., Paterson, S., McVeigh, P., Abbas Abidi, S. M., Saifullah, K., Raman, M., Ravikumar , G., LaCourse, E. J., Maule, A. G. & Brophy, P., 02 Sept 2016, In: Journal of Proteome Research. 15, 9, p. 3308-3321 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)275 Downloads (Pure) -
RNAi dynamics in juvenile Fasciola spp. liver flukes reveals the persistence of gene silencing in vitro
McVeigh, P., McCammick, E., McCusker, P., Morphew, R. M., Mousley, A., Abidi, A., Saifullah, K. M., Muthusamy, R., Gopalakrishnan, R., Spithill, T. W., Dalton, J. P., Brophy, P. M., Marks, N. J. & Maule, A. G., 25 Sept 2014, In: PLoS Neglected Tropical Diseases. 8, 9, 13 p., e3185.Research output: Contribution to journal › Article › peer-review
Open AccessFile42 Citations (Scopus)130 Downloads (Pure) -
Time-dependent tegumental surface changes in juvenile Fasciola gigantica in response to triclabendazole treatment in goat
Ahammed Shareef, P. A., Brennan, G. P., McVeigh, P., Hannan Khan, M. A., Morphew, R. M., Mousley, A., Marks, N. J., Khalid Saifullah, M. K., Brophy, P. M., Maule, A. G. & Abidi, S. M. A., Aug 2014, In: Acta Tropica. 136, p. 108-117 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)79 Downloads (Pure) -
Early hepatic and peritoneal changes and immune response in goats vaccinated with a recombinant glutathione transferase sigma class and challenged with Fasciola hepatica.
Zafra, R., Pérez-Écija, R. A., Buffoni, L., Pacheco, I. L., Martínez-Moreno, A., Lacourse , E. J., Perally, S., Brophy, P. M. & Pérez, J., 01 Jun 2013, In: Research in Veterinary Science. 94, 3, p. 602-609 8 p.Research output: Contribution to journal › Article › peer-review
27 Citations (Scopus) -
Identification of the major proteins of an immune modulating fraction from adult Fasciola hepatica released by Nonidet P40
Morphew, R. M., Hamilton, C. M., Wright, H. A., Dowling, D. J., O'Neill, S. M. & Brophy, P. M., 31 Jan 2013, In: Veterinary Parasitology. 191, 3-4, p. 379–385 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)76 Downloads (Pure) -
Anthelmintic metabolism in parasitic helminths: proteomic insights
Brophy, P. M., Mackintosh, N. & Morphew, R. M., Aug 2012, In: Parasitology. 139, 9, p. 1205-1217 13 p.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
The Sigma Class glutathione transferase from the liver fluke Fasciola hepatica
LaCourse, E. J., Perally, S., Morphew, R. M., Moxon, J. V., Prescott, M. C., Dowling, D. J., O'Neill, S. M., Kipar, A., Hetzel, U., Hoey, E., Zafra, R., Buffoni, L., Arévalo, J. P. & Brophy, P. M., 01 May 2012, In: PLoS Neglected Tropical Diseases. 6, 5, e1666.Research output: Contribution to journal › Article › peer-review
Open AccessFile64 Citations (Scopus)233 Downloads (Pure) -
Towards delineating functions within the fasciola secreted cathepsin L protease family by integrating in vivo based sub-proteomics and phylogenetics
Morphew, R. M., Wright, H. A., LaCourse, E. J., Porter, J., Barrett, J., Woods, D. J. & Brophy, P. M., 04 Jan 2011, In: PLoS Neglected Tropical Diseases. 5, 1, e-937.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Citations (Scopus)182 Downloads (Pure)