Research output per year
Research output per year
Research output
- 14 Article
- 14 results
Search results
-
2022
In silico characterisation of the complete Ly6 protein family in Fasciola gigantica supported through transcriptomics of the newly-excysted juveniles
Davey, S. D., Chalmers, I. W., Fernandez-Fuentes, N., Swain, M. T., Smith, D., Abbas Abidi, S. M., Saifullah, M. K., Raman, M., Ravikumar, G., McVeigh, P., Maule, A. G., Brophy, P. M. & Morphew, R. M., 17 Jan 2022, In: Molecular Omics. 18, 1, p. 45-56 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)79 Downloads (Pure) -
2019
X-ray structure of Fasciola hepatica Sigma class glutathione transferase 1 reveals a disulfide bond to support stability in gastro-intestinal environment
Line, K., Isupov, M. N., LaCourse, E. J., Cutress, D., Morphew, R., Brophy, P. & Littlechild, J. A., 01 Dec 2019, In: Scientific Reports. 9, 1, 902.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)183 Downloads (Pure) -
2016
Calmodulin disruption impacts growth and motility in juvenile liver fluke
McCammick, E., McVeigh, P., McCusker, P., Timson, D., Morphew, R., Brophy, P., Marks, N., Mousley, A. & Maule, A., 27 Jan 2016, In: Parasites & Vectors. 9, N/A, 13 p., 46.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus)170 Downloads (Pure) -
Exploring and Expanding the Fatty-Acid-Binding Protein Superfamily in Fasciola Species
Morphew, R., Wilkinson, T., MacKintosh, N., Jahndel, V., Paterson, S., McVeigh, P., Abbas Abidi, S. M., Saifullah, K., Raman, M., Ravikumar , G., LaCourse, E. J., Maule, A. G. & Brophy, P., 02 Sept 2016, In: Journal of Proteome Research. 15, 9, p. 3308-3321 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)275 Downloads (Pure) -
2014
RNAi dynamics in juvenile Fasciola spp. liver flukes reveals the persistence of gene silencing in vitro
McVeigh, P., McCammick, E., McCusker, P., Morphew, R. M., Mousley, A., Abidi, A., Saifullah, K. M., Muthusamy, R., Gopalakrishnan, R., Spithill, T. W., Dalton, J. P., Brophy, P. M., Marks, N. J. & Maule, A. G., 25 Sept 2014, In: PLoS Neglected Tropical Diseases. 8, 9, 13 p., e3185.Research output: Contribution to journal › Article › peer-review
Open AccessFile45 Citations (Scopus)140 Downloads (Pure) -
Time-dependent tegumental surface changes in juvenile Fasciola gigantica in response to triclabendazole treatment in goat
Ahammed Shareef, P. A., Brennan, G. P., McVeigh, P., Hannan Khan, M. A., Morphew, R. M., Mousley, A., Marks, N. J., Khalid Saifullah, M. K., Brophy, P. M., Maule, A. G. & Abidi, S. M. A., Aug 2014, In: Acta Tropica. 136, p. 108-117 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)78 Downloads (Pure) -
2013
Early hepatic and peritoneal changes and immune response in goats vaccinated with a recombinant glutathione transferase sigma class and challenged with Fasciola hepatica.
Zafra, R., Pérez-Écija, R. A., Buffoni, L., Pacheco, I. L., Martínez-Moreno, A., Lacourse , E. J., Perally, S., Brophy, P. M. & Pérez, J., 01 Jun 2013, In: Research in Veterinary Science. 94, 3, p. 602-609 8 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
Identification of the major proteins of an immune modulating fraction from adult Fasciola hepatica released by Nonidet P40
Morphew, R. M., Hamilton, C. M., Wright, H. A., Dowling, D. J., O'Neill, S. M. & Brophy, P. M., 31 Jan 2013, In: Veterinary Parasitology. 191, 3-4, p. 379–385 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)72 Downloads (Pure) -
2012
Anthelmintic metabolism in parasitic helminths: proteomic insights
Brophy, P. M., Mackintosh, N. & Morphew, R. M., Aug 2012, In: Parasitology. 139, 9, p. 1205-1217 13 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
The Sigma Class glutathione transferase from the liver fluke Fasciola hepatica
LaCourse, E. J., Perally, S., Morphew, R. M., Moxon, J. V., Prescott, M. C., Dowling, D. J., O'Neill, S. M., Kipar, A., Hetzel, U., Hoey, E., Zafra, R., Buffoni, L., Arévalo, J. P. & Brophy, P. M., 01 May 2012, In: PLoS Neglected Tropical Diseases. 6, 5, e1666.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Citations (Scopus)238 Downloads (Pure) -
2011
Towards delineating functions within the fasciola secreted cathepsin L protease family by integrating in vivo based sub-proteomics and phylogenetics
Morphew, R. M., Wright, H. A., LaCourse, E. J., Porter, J., Barrett, J., Woods, D. J. & Brophy, P. M., 04 Jan 2011, In: PLoS Neglected Tropical Diseases. 5, 1, e-937.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Citations (Scopus)178 Downloads (Pure) -
2010
Immune responses directed at egg proteins during experimental infection with the liver fluke Fasciola hepatica
Moxon, J. V., Flynn, R., Golden, O., Hamilton, J. V., Mulcahy, G. & Brophy, P. M., 01 Feb 2010, In: Parasite Immunology. 32, 2, p. 111-124 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)35 Downloads (Pure) -
Major secretory antigens of the helminth Fasciola hepatica activate a suppressive dendritic cell phenotype that attenuates Th17 cells but fails to activate Th2 immune responses
Dowling, D. J., Hamilton, C. M., Donnelly, S., La Course, J., Brophy, P. M., Dalton, J. & O'Neill, S. M., Feb 2010, In: Infection and Immunity. 78, 2, p. 793-801 9 p.Research output: Contribution to journal › Article › peer-review
117 Citations (Scopus) -
Proteomic analysis of embryonic Fasciola hepatica: Characterization and antigenic potential of a developmentally regulated heat shock protein
Moxon, J. V., LaCourse, E. J., Wright, H. A., Perally, S., Prescott, M. C., Gillard, J. L., Barrett, J., Hamilton, J. V. & Brophy, P. M., 19 Apr 2010, In: Veterinary Parasitology. 169, 1-2, p. 62-75 14 p.Research output: Contribution to journal › Article › peer-review
File33 Citations (Scopus)65 Downloads (Pure)