A common class of nematode gluthione S-transferase (GST) revealed by the theoretical proteome of the model organism Caenorhabditis elegans

Alison Mary Campbell, Peter M. Brophy, John Barrett, James R. Jefferies, Eva Liebau, Paul Teesdale-Spittle

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

The genome verified C. elegans free-living nematode model is a new tool for investigating gene expression in human and animal nematode parasites. There is limited information on designating glutathione S-transferase (GST) to specific classes in lower invertebrates such as nematodes. Following cloning, amino acid sequence alignment, recombinant expression and Western blotting we provide evidence of a new GST class in nematodes or lower invertebrates.
Original languageEnglish
Pages (from-to)701-708
Number of pages8
JournalComparative Biochemistry and Physiology - Part B: Biochemistry and Molecular Biology
Volume128
Issue number4
DOIs
Publication statusPublished - Apr 2001

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