Abstract
Modeling and simulation (M&S) techniques provide a platform for knowledge integration and hypothesis testing to gain insights into biological systems that would not be possible a priori. Agent-based modeling (ABM) is an M&S technique that focuses on describing individual components rather than homogenous populations. This tutorial introduces ABM to systems pharmacologists, using relevant case studies to highlight how ABM-specific strengths have yielded success in the area of preclinical mechanistic modeling.
Original language | English |
---|---|
Pages (from-to) | 615-629 |
Number of pages | 15 |
Journal | CPT: Pharmacometrics and Systems Pharmacology |
Volume | 4 |
Issue number | 11 |
DOIs | |
Publication status | Published - 01 Nov 2015 |
Externally published | Yes |