An infrastructure for ontology-based information systems in biomedicine: RICORDO case study

Sarala M. Wimalaratne, Pierre Grenon, Robert Hoehndorf, Georgios V. Gkoutos, Bernard de Bono

Research output: Contribution to journalArticlepeer-review

11 Citations (SciVal)

Abstract

Summary: The article presents an infrastructure for supporting the semantic interoperability of biomedical resources based on the management (storing and inference-based querying) of their ontology-based annotations. This infrastructure consists of: (i) a repository to store and query ontology-based annotations; (ii) a knowledge base server with an inference engine to support the storage of and reasoning over ontologies used in the annotation of resources; (iii) a set of applications and services allowing interaction with the integrated repository and knowledge base. The infrastructure is being prototyped and developed and evaluated by the RICORDO project in support of the knowledge management of biomedical resources, including physiology and pharmacology models and associated clinical data.Availability and implementation: The RICORDO toolkit and its source code are freely available from http://ricordo.eu/relevant-resources.Contact: sarala@ebi.ac.uk
Original languageEnglish
Pages (from-to)448-450
Number of pages3
JournalBioinformatics
Volume28
Issue number3
Early online date29 Nov 2011
DOIs
Publication statusPublished - 01 Mar 2012

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