Abstract
The problem of matching unlabeled point sets using Bayesian inference is considered. Two recently proposed models for the likelihood are compared, based on the Procrustes size-and-shape and the full configuration. Bayesian inference is carried out for matching point sets using Markov chain Monte Carlo simulation. An improvement to the existing Procrustes algorithm is proposed which improves convergence rates, using occasional large jumps in the burn-in period. The Pro-crustes and configuration methods are compared in a simulation study and using real data, where it is of interest to estimate the strengths of matches between protein binding sites. The performance of both methods is generally quite similar, and a connection between the two models is made using a Laplace approximation.
Original language | English |
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Pages (from-to) | 547-566 |
Number of pages | 20 |
Journal | Bayesian Analysis |
Volume | 7 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2012 |
Externally published | Yes |
Keywords
- Gibbs
- Markov chain Monte Carlo
- Metropolis-hastings
- Molecule
- Procrustes
- Protein
- Shape
- Size