Computer Aided Diagnosis of Prostate Cancer within the Peripheral Zone in T2-Weighted MRI

Yambu Andrik Rampun, Ling Zheng, Paul Malcolm, Reyer Zwiggelaar

Research output: Chapter in Book/Report/Conference proceedingConference Proceeding (Non-Journal item)

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Abstract

Many studies have reported the limitations of computer-aided diagnosis systems using a single T2-W MRI which include weak texture descriptors and an extensive amount of noise. Therefore, researchers have used multiparametric MRI to improve the performances of their methods. We propose a computer-aided diagnosis (CADx) method for prostate cancer within the peripheral zone using a single modality of T2-W MRI and qualitatively compared our results with some of the methods in the literature. The proposed method was tested based on 418 T2-W MR images taken from 45 patients and evaluated using 9-fold cross validation with five patients in each fold. The results demonstrated a comparable performance with CADx systems using multiparametric MRI. We achieved area under the receiver operating curve (Az) 88% ± 9% and 87% ± 10% for
Random Forest and Naive Bayes classifiers, respectively, while the combined classifier
achieved 91% ±7%.
Original languageEnglish
Title of host publicationProceedings of the 19th Medical Image Understanding and Analysis Conference
Pages207-212
Number of pages6
Publication statusPublished - 15 Jul 2015

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