Controlling tuberculosis in a llama (Lama glama) herd using clinical signs, tuberculin skin testing and serology

D. F. Twomey; R. Collins; M. P. Cranwell; T. R. Crawshaw; R. J. Higgins; G. S. Dean; H. M. Vordermeier; A. Hollingdale; R. de la Rua-Domenech

doi:10.1016/j.tvjl.2011.05.014

Controlling tuberculosis in a llama (Lama glama) herd using clinical signs, tuberculin skin testing and serology

D. F. Twomey^*, R. Collins, M. P. Cranwell, T. R. Crawshaw, R. J. Higgins, G. S. Dean, H. M. Vordermeier, A. Hollingdale, R. de la Rua-Domenech

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

An outbreak of tuberculosis (TB), caused by Mycobacterium bovis, was investigated in a small herd of llamas (Lama glama). Based on three ante-mortem diagnostic methods (clinical signs, tuberculin skin test reactions, and 'Rapid Test' serology), 12 llamas were selected for examination post-mortem. Grossly visible lesions suspicious of TB were observed in eight animals, four of which had exhibited clinical signs, one was a skin test 'reactor', and three had been seropositive. M. bovis was isolated from seven of these eight animals. Clinical signs combined with serology were found to be useful in identifying infected animals, but tuberculin skin testing had limited negative predictive value as four llamas that were subsequently confirmed as infected were not detected using this assay.

Original language	English
Pages (from-to)	246-248
Number of pages	3
Journal	Veterinary Journal
Volume	192
Issue number	2
Early online date	24 Jun 2011
DOIs	https://doi.org/10.1016/j.tvjl.2011.05.014
Publication status	Published - 01 May 2012

Keywords

Clinical disease
Llama (Lama glama)
Rapid Test serology
Tuberculin skin test
Tuberculosis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tvjl.2011.05.014

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abstract = "An outbreak of tuberculosis (TB), caused by Mycobacterium bovis, was investigated in a small herd of llamas (Lama glama). Based on three ante-mortem diagnostic methods (clinical signs, tuberculin skin test reactions, and 'Rapid Test' serology), 12 llamas were selected for examination post-mortem. Grossly visible lesions suspicious of TB were observed in eight animals, four of which had exhibited clinical signs, one was a skin test 'reactor', and three had been seropositive. M. bovis was isolated from seven of these eight animals. Clinical signs combined with serology were found to be useful in identifying infected animals, but tuberculin skin testing had limited negative predictive value as four llamas that were subsequently confirmed as infected were not detected using this assay.",

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AU - Crawshaw, T. R.

AU - Higgins, R. J.

AU - Dean, G. S.

AU - Vordermeier, H. M.

AU - Hollingdale, A.

AU - de la Rua-Domenech, R.

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KW - Llama (Lama glama)

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Controlling tuberculosis in a llama (Lama glama) herd using clinical signs, tuberculin skin testing and serology

Abstract

Keywords

UN SDGs

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