Development of immune-diagnostic reagents to diagnose bovine tuberculosis in cattle

H. Martin Vordermeier*, Gareth J. Jones, Bryce M. Buddle, R. Glyn Hewinson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Bovine tuberculosis remains a major economic and animal welfare concern worldwide. As part of control strategies, cattle vaccination is being considered. This approach, used alongside conventional control policies, also requires the development of vaccine compatible diagnostic assays to distinguish infected from vaccinated animals (DIVA). In this review we discuss recent advances in DIVA development based on the detection of host cellular immune responses by blood testing or skin testing approaches.

Original languageEnglish
Pages (from-to)10-14
Number of pages5
JournalVeterinary Immunology and Immunopathology
Early online date10 Feb 2016
Publication statusPublished - 15 Nov 2016


  • BCG
  • Cattle
  • Differential diagnosis
  • Tuberculosis
  • Vaccination


Dive into the research topics of 'Development of immune-diagnostic reagents to diagnose bovine tuberculosis in cattle'. Together they form a unique fingerprint.

Cite this