Development of immune-diagnostic reagents to diagnose bovine tuberculosis in cattle

H. Martin Vordermeier; Gareth J. Jones; Bryce M. Buddle; R. Glyn Hewinson

doi:10.1016/j.vetimm.2016.02.003

Development of immune-diagnostic reagents to diagnose bovine tuberculosis in cattle

H. Martin Vordermeier^*
, Gareth J. Jones
, Bryce M. Buddle
, R. Glyn Hewinson

^*Corresponding author for this work

Bovine TB, diseases and control

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Bovine tuberculosis remains a major economic and animal welfare concern worldwide. As part of control strategies, cattle vaccination is being considered. This approach, used alongside conventional control policies, also requires the development of vaccine compatible diagnostic assays to distinguish infected from vaccinated animals (DIVA). In this review we discuss recent advances in DIVA development based on the detection of host cellular immune responses by blood testing or skin testing approaches.

Original language	English
Pages (from-to)	10-14
Number of pages	5
Journal	Veterinary Immunology and Immunopathology
Volume	181
Early online date	10 Feb 2016
DOIs	https://doi.org/10.1016/j.vetimm.2016.02.003
Publication status	Published - 15 Nov 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

BCG
Cattle
Differential diagnosis
Tuberculosis
Vaccination

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abstract = "Bovine tuberculosis remains a major economic and animal welfare concern worldwide. As part of control strategies, cattle vaccination is being considered. This approach, used alongside conventional control policies, also requires the development of vaccine compatible diagnostic assays to distinguish infected from vaccinated animals (DIVA). In this review we discuss recent advances in DIVA development based on the detection of host cellular immune responses by blood testing or skin testing approaches.",

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AU - Jones, Gareth J.

AU - Buddle, Bryce M.

AU - Hewinson, R. Glyn

PY - 2016/11/15

Y1 - 2016/11/15

N2 - Bovine tuberculosis remains a major economic and animal welfare concern worldwide. As part of control strategies, cattle vaccination is being considered. This approach, used alongside conventional control policies, also requires the development of vaccine compatible diagnostic assays to distinguish infected from vaccinated animals (DIVA). In this review we discuss recent advances in DIVA development based on the detection of host cellular immune responses by blood testing or skin testing approaches.

AB - Bovine tuberculosis remains a major economic and animal welfare concern worldwide. As part of control strategies, cattle vaccination is being considered. This approach, used alongside conventional control policies, also requires the development of vaccine compatible diagnostic assays to distinguish infected from vaccinated animals (DIVA). In this review we discuss recent advances in DIVA development based on the detection of host cellular immune responses by blood testing or skin testing approaches.

KW - BCG

KW - Cattle

KW - Differential diagnosis

KW - Tuberculosis

KW - Vaccination

UR - https://www.scopus.com/pages/publications/84958568406

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DO - 10.1016/j.vetimm.2016.02.003

M3 - Article

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AN - SCOPUS:84958568406

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JO - Veterinary Immunology and Immunopathology

JF - Veterinary Immunology and Immunopathology

ER -

Development of immune-diagnostic reagents to diagnose bovine tuberculosis in cattle

Abstract

UN SDGs

Keywords

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