ESAT-6 peptide recognition by bovine CD8+ lymphocytes of naturally infected cows in herds from southern Italy

Fabrizio Vitale; Stefano Reale; Enrico Petrotta; Santo Caracappa; Annalisa Barera; Marco Pio La Manna; Pasquale Macaluso; Nadia Caccamo; Francesco Dieli; Hans Martin Vordermeier; Guido Sireci; Alfredo Salerno

doi:10.1128/CVI.13.4.530-533.2006

ESAT-6 peptide recognition by bovine CD8⁺ lymphocytes of naturally infected cows in herds from southern Italy

Fabrizio Vitale, Stefano Reale, Enrico Petrotta, Santo Caracappa, Annalisa Barera, Marco Pio La Manna, Pasquale Macaluso, Nadia Caccamo, Francesco Dieli, Hans Martin Vordermeier, Guido Sireci, Alfredo Salerno

Bovine TB, diseases and control

Research output: Contribution to journal › Article › peer-review

Abstract

The aim of this study was to define epitopes of Mycobacterium bovis from ESAT-6 (early secretory antigen of 6 kDa) recognized by CD8⁺ T lymphocytes from cows naturally infected with Mycobacterium bovis. We found that bovine CD8⁺ T cells recognized 10 out of 11 ESAT-6 peptides tested.

Original language	English
Pages (from-to)	530-533
Number of pages	4
Journal	Clinical and Vaccine Immunology
Volume	13
Issue number	4
DOIs	https://doi.org/10.1128/CVI.13.4.530-533.2006
Publication status	Published - 07 Apr 2006

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Vitale, F., Reale, S., Petrotta, E., Caracappa, S., Barera, A., La Manna, M. P., Macaluso, P., Caccamo, N., Dieli, F., Vordermeier, H. M., Sireci, G., & Salerno, A. (2006). ESAT-6 peptide recognition by bovine CD8⁺ lymphocytes of naturally infected cows in herds from southern Italy. Clinical and Vaccine Immunology, 13(4), 530-533. https://doi.org/10.1128/CVI.13.4.530-533.2006

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abstract = "The aim of this study was to define epitopes of Mycobacterium bovis from ESAT-6 (early secretory antigen of 6 kDa) recognized by CD8+ T lymphocytes from cows naturally infected with Mycobacterium bovis. We found that bovine CD8+ T cells recognized 10 out of 11 ESAT-6 peptides tested.",

author = "Fabrizio Vitale and Stefano Reale and Enrico Petrotta and Santo Caracappa and Annalisa Barera and {La Manna}, {Marco Pio} and Pasquale Macaluso and Nadia Caccamo and Francesco Dieli and Vordermeier, {Hans Martin} and Guido Sireci and Alfredo Salerno",

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Vitale, F, Reale, S, Petrotta, E, Caracappa, S, Barera, A, La Manna, MP, Macaluso, P, Caccamo, N, Dieli, F, Vordermeier, HM, Sireci, G & Salerno, A 2006, 'ESAT-6 peptide recognition by bovine CD8⁺ lymphocytes of naturally infected cows in herds from southern Italy', Clinical and Vaccine Immunology, vol. 13, no. 4, pp. 530-533. https://doi.org/10.1128/CVI.13.4.530-533.2006

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AU - Vitale, Fabrizio

AU - Reale, Stefano

AU - Petrotta, Enrico

AU - Caracappa, Santo

AU - Barera, Annalisa

AU - La Manna, Marco Pio

AU - Macaluso, Pasquale

AU - Caccamo, Nadia

AU - Dieli, Francesco

AU - Vordermeier, Hans Martin

AU - Sireci, Guido

AU - Salerno, Alfredo

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AB - The aim of this study was to define epitopes of Mycobacterium bovis from ESAT-6 (early secretory antigen of 6 kDa) recognized by CD8+ T lymphocytes from cows naturally infected with Mycobacterium bovis. We found that bovine CD8+ T cells recognized 10 out of 11 ESAT-6 peptides tested.

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ESAT-6 peptide recognition by bovine CD8⁺ lymphocytes of naturally infected cows in herds from southern Italy

Abstract

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