ESAT-6 peptide recognition by bovine CD8+ lymphocytes of naturally infected cows in herds from southern Italy

  • Fabrizio Vitale
  • , Stefano Reale
  • , Enrico Petrotta
  • , Santo Caracappa
  • , Annalisa Barera
  • , Marco Pio La Manna
  • , Pasquale Macaluso
  • , Nadia Caccamo
  • , Francesco Dieli
  • , Hans Martin Vordermeier
  • , Guido Sireci*
  • , Alfredo Salerno
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

The aim of this study was to define epitopes of Mycobacterium bovis from ESAT-6 (early secretory antigen of 6 kDa) recognized by CD8+ T lymphocytes from cows naturally infected with Mycobacterium bovis. We found that bovine CD8+ T cells recognized 10 out of 11 ESAT-6 peptides tested.

Original languageEnglish
Pages (from-to)530-533
Number of pages4
JournalClinical and Vaccine Immunology
Volume13
Issue number4
DOIs
Publication statusPublished - 07 Apr 2006

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