TY - JOUR
T1 - FERONIA receptor kinase pathway suppresses abscisic acid signaling in Arabidopsis by activating ABI2 phosphatase
AU - Yu, Feng
AU - Qian, Lichao
AU - Nibau, Candida Sofia
AU - Duan, Qiaohong
AU - Kita, Daniel
AU - Levasseur, Kathryn
AU - Li, Xiaoqian
AU - Lu, Changqing
AU - Li, Hui
AU - Hou, Congcong
AU - Li, Legong
AU - Buchanan, Bob B.
AU - Chen, Liangbi
AU - Cheung, Alice Y.
AU - Li, Dongping
AU - Luan, Sheng
N1 - Yu, F., Qian, L., Nibau, C. S., Duan, Q., Kita, D., Levasseur, K., Li, X., Lu, C., Li, H., Hou, C., Li, L., Buchanan, B. B., Chen, L., Cheung, A. Y., Li, D., Luan, S. (2012). FERONIA receptor kinase pathway suppresses abscisic acid signaling in Arabidopsis by activating ABI2 phosphatase. PNAS, 109 (36), 14693-14698.
PY - 2012/9/4
Y1 - 2012/9/4
N2 - Plant growth and development are controlled by a delicate balance of hormonal cues. Growth-promoting hormones and growth-inhibiting counterparts often antagonize each other in their action, but the molecular mechanisms underlying these events remain largely unknown. Here, we report a cross-talk mechanism that enables a receptor-like kinase, FERONIA (FER), a positive regulator of auxin-promoted growth, to suppress the abscisic acid (ABA) response through activation of ABI2, a negative regulator of ABA signaling. The FER pathway consists of a FER kinase interacting with guanine exchange factors GEF1, GEF4, and GEF10 that, in turn, activate GTPase ROP11/ARAC10. Arabidopsis mutants disrupted in any step of the FER pathway, including fer, gef1gef4gef10, or rop11/arac10, all displayed an ABA-hypersensitive response, implicating the FER pathway in the suppression mechanism. In search of the target for the FER pathway, we found that the ROP11/ARAC10 protein physically interacted with the ABI2 phosphatase and enhanced its activity, thereby linking the FER pathway with the inhibition of ABA signaling.
AB - Plant growth and development are controlled by a delicate balance of hormonal cues. Growth-promoting hormones and growth-inhibiting counterparts often antagonize each other in their action, but the molecular mechanisms underlying these events remain largely unknown. Here, we report a cross-talk mechanism that enables a receptor-like kinase, FERONIA (FER), a positive regulator of auxin-promoted growth, to suppress the abscisic acid (ABA) response through activation of ABI2, a negative regulator of ABA signaling. The FER pathway consists of a FER kinase interacting with guanine exchange factors GEF1, GEF4, and GEF10 that, in turn, activate GTPase ROP11/ARAC10. Arabidopsis mutants disrupted in any step of the FER pathway, including fer, gef1gef4gef10, or rop11/arac10, all displayed an ABA-hypersensitive response, implicating the FER pathway in the suppression mechanism. In search of the target for the FER pathway, we found that the ROP11/ARAC10 protein physically interacted with the ABI2 phosphatase and enhanced its activity, thereby linking the FER pathway with the inhibition of ABA signaling.
UR - http://hdl.handle.net/2160/11334
U2 - 10.1073/pnas.1212547109
DO - 10.1073/pnas.1212547109
M3 - Article
C2 - 22908257
SN - 1091-6490
VL - 109
SP - 14693
EP - 14698
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 36
ER -