Genetic transformation of protoplasts isolated from leaves of lolium temulentum and lolium perenne

Huw R. Davis, Anne L. Maddison, Dylan W. Phillips, Huw D. Jones*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Citations (Scopus)

Abstract

Transient expression of inserted recombinant DNA in plant protoplasts is a widely used tool for functional genomics research. Recently it has been utilized to screen potential sgRNA guides for CRISPR-mediated genome editing. However, little research has been conducted into the use of transient expression of protoplasts in Lolium perenne (a globally important pasture, hay, and amenity grass), and no studies have been conducted into Lolium temulentum (a weed in cereal crops but a potentially useful model species for Lolium research). In this chapter, we describe a methodology of protoplast extraction and transformation from 14-day-old leaf mesophyll cells from L. perenne and L. temulentum. We believe this is the first report of a procedure for obtaining high density, viable protoplasts from L. temulentum. The method of polyethylene glycol (PEG)-mediated transformation is also described to achieve genetic transformation of protoplasts.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages199-205
Number of pages7
DOIs
Publication statusPublished - 2020

Publication series

NameMethods in Molecular Biology
Volume2072
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Lolium perenne
  • Lolium temulentum
  • PEG-mediated transformation
  • Protoplasts
  • Transient expression

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