Glycomics-driven discoveries in schistosome research

Cornelis H. Hokke, André M. Deelder, Karl F Hoffmann, Manfred Wuhrer

Research output: Contribution to journalArticlepeer-review

Abstract

Schistosome glycans and glycoconjugates play a prominent role in the parasite's biology, in particular in the interaction with the human host. A large amount of structural data regarding glycosylation of different schistosome life stages and glycoconjugate subsets has been collected in the last decade, but many significant gaps in our knowledge of the schistosomal glycome remain. Here we will present a concise review of the already available data guided by a selection of recently generated stage-specific glycan profiles, and discuss implications and prospects of glycomics studies of schistosomes.
Original languageEnglish
Pages (from-to)275-283
Number of pages9
JournalExperimental Parasitology
Volume117
Issue number3
Early online date17 Jun 2007
DOIs
Publication statusPublished - Nov 2007

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